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The map label for this gene is argJ

Identifier: 41407460

GI number: 41407460

Start: 1464529

End: 1465743

Strand: Direct

Name: argJ

Synonym: MAP1362

Alternate gene names: 41407460

Gene position: 1464529-1465743 (Clockwise)

Preceding gene: 41407459

Following gene: 41407461

Centisome position: 30.32

GC content: 72.76

Gene sequence:

>1215_bases
GTGACCGAGACGGTGAACGCGGCGCGGCTGCTGCGCGAGCAGGGCGTCACCGCGCCGGCCGGCTTCCGGGCCGCCGGCAT
CGCCGCGGGGATCAAGGCGTCGGGCAAGCGCGACCTGGCCCTGGTCTTCAACGAGGGACCCGACTACGGCGCCGCCGGCG
TGTTCACCCGCAACAAGGTCAAGGCCGCCCCGGTGCTGTGGAGCCAGCAGGTGCTGACCACCGGCGCGTTGCGCGCCGTC
ATCCTGAACTCGGGCGGCGCCAACGCCTGCACCGGGCCGGGCGGCTTCCAGGATGCCCACGCCACCGCCGAAGCCGTCGC
CGCCGCGCTGTCGGACTGGGGCACCGAGACCGGCGCCATCGAGGTCGCGGTGTGCTCCACCGGGCTGATCGGCGACCGGC
TGCCGATGGACAAGCTGCTCGCCGGGGTGCGCACCATCGTGCAGGACATGGCCGGCGGCCTGTCCGGCGGCGACGACGCC
GCGCAGGCCATCATGACCACCGACACCGTGCCCAAACAGGTTGCGCTGCACCATCCTGGCAACTGGACCGTCGGCGGGAT
GGCCAAGGGCGCGGGCATGATCGCACCGTCGCTGGCCACCATGCTGTGCGTGCTCACCACCGACGCGGCCGTCGACCCGG
TGGCGCTGGACACCGCGCTGCGCCGCGCCACCGCCGCCACCTTCGACCGGCTCGACATCGACGGCGCGTGTTCGACCAAC
GACACGGTGCTGCTGCTGGCCTCCGGGGCCAGCGGGATCACGCCGGCGCAGGCCGACCTCGACGACGCGGTGCTGCGGGT
CTGCGATGACCTGTGCGCTCAGCTGCAGGCCGACGCCGAGGGCGTCACCAAACGTGTCAACGTCACCGTCACCGGCGCGG
CCAGTGACGACGACGCCGTCGTCGCCGCCCGGACCATCGCCCGCGACAGCCTGGTCAAGACGGCGGTGTTCGGCTCCGAC
CCCAACTGGGGCCGGGTGGTCGCCGCCGTCGGCATCGCGCCGATCGCGCTGGATCCCGACCGGATGACGGTGTCGTTCAA
CGGTTCCGCGGTCTTCGCCGACGGCGTCGGCACACCCGGCGCGCGGGAGGTGGACCTGTCCGGGCCCGACATCGACATCA
CCGTCGACCTGCGGCTCGGCGACGGGCGGGCCACCGTCCGCACCACCGACCTGTCGCACGGCTACGTCGAAGAGAATTCG
GCCTACAGCTCATGA

Upstream 100 bases:

>100_bases
ACAACCTGGTCAAGGGAACCGCCGGGGCGGCCGTGCAGTCGATGAACCTGGCGCTGGGTTGGCCGGAGACACAAGGACTT
TCGGTGATCGGGGTGGCGCC

Downstream 100 bases:

>100_bases
CGCCCTCGACCGAAGCGCTGCCCACCGCGGTCAAGGCGCAGGTGCTGGCCGAAGCGCTGCCCTGGCTCAAGCAGCTGCAC
GGCAAGATTGTGGTGATCAA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGPDYGAAGVFTRNKVKAAPVLWSQQVLTTGALRAV
ILNSGGANACTGPGGFQDAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVRTIVQDMAGGLSGGDDA
AQAIMTTDTVPKQVALHHPGNWTVGGMAKGAGMIAPSLATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTN
DTVLLLASGASGITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDDDAVVAARTIARDSLVKTAVFGSD
PNWGRVVAAVGIAPIALDPDRMTVSFNGSAVFADGVGTPGAREVDLSGPDIDITVDLRLGDGRATVRTTDLSHGYVEENS
AYSS

Sequences:

>Translated_404_residues
MTETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGPDYGAAGVFTRNKVKAAPVLWSQQVLTTGALRAV
ILNSGGANACTGPGGFQDAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVRTIVQDMAGGLSGGDDA
AQAIMTTDTVPKQVALHHPGNWTVGGMAKGAGMIAPSLATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTN
DTVLLLASGASGITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDDDAVVAARTIARDSLVKTAVFGSD
PNWGRVVAAVGIAPIALDPDRMTVSFNGSAVFADGVGTPGAREVDLSGPDIDITVDLRLGDGRATVRTTDLSHGYVEENS
AYSS
>Mature_403_residues
TETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGPDYGAAGVFTRNKVKAAPVLWSQQVLTTGALRAVI
LNSGGANACTGPGGFQDAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVRTIVQDMAGGLSGGDDAA
QAIMTTDTVPKQVALHHPGNWTVGGMAKGAGMIAPSLATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTND
TVLLLASGASGITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDDDAVVAARTIARDSLVKTAVFGSDP
NWGRVVAAVGIAPIALDPDRMTVSFNGSAVFADGVGTPGAREVDLSGPDIDITVDLRLGDGRATVRTTDLSHGYVEENSA
YSS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=420, Percent_Identity=37.6190476190476, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_MYCPA (P62063)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_960296.1
- ProteinModelPortal:   P62063
- SMR:   P62063
- MEROPS:   T05.001
- EnsemblBacteria:   EBMYCT00000038357
- GeneID:   2719976
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP1362
- NMPDR:   fig|262316.1.peg.1362
- GeneTree:   EBGT00050000016724
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- ProtClustDB:   PRK05388
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 40929; Mature: 40798

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGPDYGAAGVFTRNKV
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCCC
KAAPVLWSQQVLTTGALRAVILNSGGANACTGPGGFQDAHATAEAVAAALSDWGTETGAI
EECCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
EVAVCSTGLIGDRLPMDKLLAGVRTIVQDMAGGLSGGDDAAQAIMTTDTVPKQVALHHPG
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCEEEEECCC
NWTVGGMAKGAGMIAPSLATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTN
CEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DTVLLLASGASGITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDDDAV
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCE
VAARTIARDSLVKTAVFGSDPNWGRVVAAVGIAPIALDPDRMTVSFNGSAVFADGVGTPG
EHHHHHHHHHHHHHEEECCCCCCCEEEEEECCEEEEECCCCEEEEECCCEEEECCCCCCC
AREVDLSGPDIDITVDLRLGDGRATVRTTDLSHGYVEENSAYSS
CEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCEECCCCCCCC
>Mature Secondary Structure 
TETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGPDYGAAGVFTRNKV
CCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEECCCC
KAAPVLWSQQVLTTGALRAVILNSGGANACTGPGGFQDAHATAEAVAAALSDWGTETGAI
EECCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
EVAVCSTGLIGDRLPMDKLLAGVRTIVQDMAGGLSGGDDAAQAIMTTDTVPKQVALHHPG
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCEEEEECCC
NWTVGGMAKGAGMIAPSLATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTN
CEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DTVLLLASGASGITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDDDAV
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCE
VAARTIARDSLVKTAVFGSDPNWGRVVAAVGIAPIALDPDRMTVSFNGSAVFADGVGTPG
EHHHHHHHHHHHHHEEECCCCCCCEEEEEECCEEEEECCCCEEEEECCCEEEECCCCCCC
AREVDLSGPDIDITVDLRLGDGRATVRTTDLSHGYVEENSAYSS
CEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA