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The map label for this gene is argC

Identifier: 41407459

GI number: 41407459

Start: 1463489

End: 1464532

Strand: Direct

Name: argC

Synonym: MAP1361

Alternate gene names: 41407459

Gene position: 1463489-1464532 (Clockwise)

Preceding gene: 41407458

Following gene: 41407460

Centisome position: 30.3

GC content: 73.47

Gene sequence:

>1044_bases
ATGGCCGACGTGATGAGGGTGGCGGTAGCCGGTGCCAGCGGCTATGCGGGCGGTGAGATCCTACGCCTGCTGCTCGGGCA
CCCGGCTTACGCCCAGGGGCGGCTGGCGATCGGCGCGGTGACCGCCGCGGCCAGCGCCGGCAGCCCACTCGGCGAGCATC
ACCCGCACCTGACGCCGTTGGCCCAGCGCGTGCTGGAGCCCACCGACGCCGCCGTGCTGGCCGGCCACGACGTGGTGTTT
CTGGCGTTGCCGCACGGACATTCGGCGGCGCTGGCCGACCAGCTCGGCGCCGACACGCTGATCGTCGACTGCGGCGCGGA
CTTCCGGCTGACCGACGCCGCCGCCTGGGAGCGGTTCTACGGCTCGCCGCACGCCGGCAGTTGGCCCTACGGGCTGCCGG
AGCTGCCCGGGGCGCGCGAGCGGCTGCGCGGCGCCCGCCGGATCGCGGTGCCGGGCTGCTACCCGACCGCGGCGCTGCTG
GCCCTGCTGCCCGCGATGGCCGAGGACCTGATCGAGCCCGCCGTCACCGTGGTCGCCGTCAGCGGCACCTCCGGAGCCGG
TCGCGCCGCCAAGACCGACCTACTGGGCTCGGAGGTCATCGGGTCGGCGCGGGCCTACAACATCGCCGGGGCGCACCGGC
ACACCCCCGAGATCGCCCAGGGCCTGGCGGCCGTGTCCGGACGCGACGTCACGGTGTCGTTCACCCCGGTGCTGATCCCG
ACCTCGCGCGGCATCCTGGCCACCTGCACCGCCCGCACCACCGCGCCGTTTTCGGCGCTTCGGGCCGCATACGAAAAGGC
TTATGACGCAGAGCCTTTCATCTACCTGATGCCCGAGGGACAGCTGCCGCGGACCGGGGCGGTGATCGGCAGCAACGCGG
CGCACATCGCGGTGGCGGTGGACGAGGCGGCGGGCGTGCTGGTGGCGATCGCCGCGATCGACAACCTGGTCAAGGGAACC
GCCGGGGCGGCCGTGCAGTCGATGAACCTGGCGCTGGGTTGGCCGGAGACACAAGGACTTTCGGTGATCGGGGTGGCGCC
GTGA

Upstream 100 bases:

>100_bases
ACGCCGCGGTGCGCCGGGCCGCCGAGGCGGTCGGCGCCGAGCTGCGCACCTAGATGGAATGGATTTGCAAAGTACTGCAT
AACCATGCAGAATCGTCCAA

Downstream 100 bases:

>100_bases
CCGAGACGGTGAACGCGGCGCGGCTGCTGCGCGAGCAGGGCGTCACCGCGCCGGCCGGCTTCCGGGCCGCCGGCATCGCC
GCGGGGATCAAGGCGTCGGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLAIGAVTAAASAGSPLGEHHPHLTPLAQRVLEPTDAAVLAGHDVVF
LALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFYGSPHAGSWPYGLPELPGARERLRGARRIAVPGCYPTAALL
ALLPAMAEDLIEPAVTVVAVSGTSGAGRAAKTDLLGSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIP
TSRGILATCTARTTAPFSALRAAYEKAYDAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEAAGVLVAIAAIDNLVKGT
AGAAVQSMNLALGWPETQGLSVIGVAP

Sequences:

>Translated_347_residues
MADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLAIGAVTAAASAGSPLGEHHPHLTPLAQRVLEPTDAAVLAGHDVVF
LALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFYGSPHAGSWPYGLPELPGARERLRGARRIAVPGCYPTAALL
ALLPAMAEDLIEPAVTVVAVSGTSGAGRAAKTDLLGSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIP
TSRGILATCTARTTAPFSALRAAYEKAYDAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEAAGVLVAIAAIDNLVKGT
AGAAVQSMNLALGWPETQGLSVIGVAP
>Mature_346_residues
ADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLAIGAVTAAASAGSPLGEHHPHLTPLAQRVLEPTDAAVLAGHDVVFL
ALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFYGSPHAGSWPYGLPELPGARERLRGARRIAVPGCYPTAALLA
LLPAMAEDLIEPAVTVVAVSGTSGAGRAAKTDLLGSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIPT
SRGILATCTARTTAPFSALRAAYEKAYDAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAVDEAAGVLVAIAAIDNLVKGTA
GAAVQSMNLALGWPETQGLSVIGVAP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=356, Percent_Identity=37.3595505617978, Blast_Score=155, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6320913, Length=360, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35252; Mature: 35120

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLAIGAVTAAASAGSPLGEHHPHLTPL
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCHH
AQRVLEPTDAAVLAGHDVVFLALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFY
HHHHCCCCCCEEEECCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCEECHHHHHHHHC
GSPHAGSWPYGLPELPGARERLRGARRIAVPGCYPTAALLALLPAMAEDLIEPAVTVVAV
CCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
SGTSGAGRAAKTDLLGSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIP
ECCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEE
TSRGILATCTARTTAPFSALRAAYEKAYDAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCEEEEEEE
DEAAGVLVAIAAIDNLVKGTAGAAVQSMNLALGWPETQGLSVIGVAP
CCCCCHHHHHHHHHHHHHCCCCHHHEECEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
ADVMRVAVAGASGYAGGEILRLLLGHPAYAQGRLAIGAVTAAASAGSPLGEHHPHLTPL
CCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCHH
AQRVLEPTDAAVLAGHDVVFLALPHGHSAALADQLGADTLIVDCGADFRLTDAAAWERFY
HHHHCCCCCCEEEECCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCEECHHHHHHHHC
GSPHAGSWPYGLPELPGARERLRGARRIAVPGCYPTAALLALLPAMAEDLIEPAVTVVAV
CCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
SGTSGAGRAAKTDLLGSEVIGSARAYNIAGAHRHTPEIAQGLAAVSGRDVTVSFTPVLIP
ECCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEE
TSRGILATCTARTTAPFSALRAAYEKAYDAEPFIYLMPEGQLPRTGAVIGSNAAHIAVAV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCEEEEEEE
DEAAGVLVAIAAIDNLVKGTAGAAVQSMNLALGWPETQGLSVIGVAP
CCCCCHHHHHHHHHHHHHCCCCHHHEECEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA