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The map label for this gene is corA-1 [H]

Identifier: 39996501

GI number: 39996501

Start: 1538072

End: 1539136

Strand: Reverse

Name: corA-1 [H]

Synonym: GSU1399

Alternate gene names: 39996501

Gene position: 1539136-1538072 (Counterclockwise)

Preceding gene: 39996505

Following gene: 39996500

Centisome position: 40.35

GC content: 59.53

Gene sequence:

>1065_bases
ATGAAAAAAATCATCAAGCAACGTTCCCGCAAGACAGGCCTTCCTCCCGGCAGTCTGGTCCACATCGGCGAGCAGACCGG
CGAACCGGTCCGGATATCCCTTGTCGACTACGACGAAACGAGCATCAGCGAGCGGGAAACGGACGACATTGCCGAGTGTT
TTCCCCATAGCGACCAGCCGGGGGTGCGGTGGCTCGACATGGAGGGTATCCACCGGCCCGAACTGCTCAAGACACTCGGC
GAATGCTACGGTATCCACCCCCTCACCCTCGAAGACATCCTCAATACCGACCAGCGCCCCAAACTGGAGGACTTCGACGA
CTATCTCTTCGTGGTCCTGAAGATGCTCTCCCTCCAGCCGGATGGCTCGCTTACCGCGGAACAGGTCAGCTTCGTGCTCG
GCCCCTCGTTTCTCATCTCCTTCCAGGAAGGATTCAAGGGAGACCTCTTCGACTCCATCCGCCGGCGCCTGAGGGAAAAC
CGGGGCAAGCTTCGCAAGAGCGGGTCCGACTTTCTGCTCTACTCACTCATGGACGCCATTGTGGACTACTACTTCGTGAT
CCTCGAAGATCTGGCCGAGCGGATCGAGGAACTGGAAGAAGAAGTCATCGCCGGCCCCAGCCGCAAGACGGTCGTGAAGA
TCCAGCACCTCAAGCGGGAAACCATCTTTCTGCGCAAATCCGTCTGGCCCCTGCGAGAGGTGCTGGGACGGCTGGAGCGG
CGCGAATCGCCCCTGGTGCGCGGCGAAACCGTCATCTACCTGCGGGACGTCTACGACCACTGCATCCAGATCATCGAAAC
CGTGGAGACCTTCCGGGACCTCCTGTCGGAGATCCTCGACATCTACCTCTCCGCCATCGGCAACCGGACCAACGAAGTGA
TGAAGGTGCTCACCATCATCGCCACCATCTTCATGCCGCTCACCTTCATCGCCGGGGTCTATGGCATGAACTTCCGCTAC
ATGCCCGAGCTCGAATGGCACTGGGGCTACCCGGCCGTTCTCCTGCTGATGCTCCTGGTAAGCCTGGGTATGGGAATATT
CTTCCGGCGCAAGAGATGGCTGTAG

Upstream 100 bases:

>100_bases
AACCTCGGACGACACCGTCGGGAGCCTGCTCAAGCGGACCGACGAACTCCTGTACCGGAGCAAGGGTGCCGGACGCAACT
GCGTCACCTGCGCATAGACT

Downstream 100 bases:

>100_bases
CACAAGGCTAGTGAAACAATTTACCAACAAAAATTTGTTGGGCGCTTTGGACAAACCGCCGGCTGTCGGCTATGCTAATA
CCCAATCGTGCGTTCATCGC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKKIIKQRSRKTGLPPGSLVHIGEQTGEPVRISLVDYDETSISERETDDIAECFPHSDQPGVRWLDMEGIHRPELLKTLG
ECYGIHPLTLEDILNTDQRPKLEDFDDYLFVVLKMLSLQPDGSLTAEQVSFVLGPSFLISFQEGFKGDLFDSIRRRLREN
RGKLRKSGSDFLLYSLMDAIVDYYFVILEDLAERIEELEEEVIAGPSRKTVVKIQHLKRETIFLRKSVWPLREVLGRLER
RESPLVRGETVIYLRDVYDHCIQIIETVETFRDLLSEILDIYLSAIGNRTNEVMKVLTIIATIFMPLTFIAGVYGMNFRY
MPELEWHWGYPAVLLLMLLVSLGMGIFFRRKRWL

Sequences:

>Translated_354_residues
MKKIIKQRSRKTGLPPGSLVHIGEQTGEPVRISLVDYDETSISERETDDIAECFPHSDQPGVRWLDMEGIHRPELLKTLG
ECYGIHPLTLEDILNTDQRPKLEDFDDYLFVVLKMLSLQPDGSLTAEQVSFVLGPSFLISFQEGFKGDLFDSIRRRLREN
RGKLRKSGSDFLLYSLMDAIVDYYFVILEDLAERIEELEEEVIAGPSRKTVVKIQHLKRETIFLRKSVWPLREVLGRLER
RESPLVRGETVIYLRDVYDHCIQIIETVETFRDLLSEILDIYLSAIGNRTNEVMKVLTIIATIFMPLTFIAGVYGMNFRY
MPELEWHWGYPAVLLLMLLVSLGMGIFFRRKRWL
>Mature_354_residues
MKKIIKQRSRKTGLPPGSLVHIGEQTGEPVRISLVDYDETSISERETDDIAECFPHSDQPGVRWLDMEGIHRPELLKTLG
ECYGIHPLTLEDILNTDQRPKLEDFDDYLFVVLKMLSLQPDGSLTAEQVSFVLGPSFLISFQEGFKGDLFDSIRRRLREN
RGKLRKSGSDFLLYSLMDAIVDYYFVILEDLAERIEELEEEVIAGPSRKTVVKIQHLKRETIFLRKSVWPLREVLGRLER
RESPLVRGETVIYLRDVYDHCIQIIETVETFRDLLSEILDIYLSAIGNRTNEVMKVLTIIATIFMPLTFIAGVYGMNFRY
MPELEWHWGYPAVLLLMLLVSLGMGIFFRRKRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=131, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787604, Length=237, Percent_Identity=22.3628691983122, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41104; Mature: 41104

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIKQRSRKTGLPPGSLVHIGEQTGEPVRISLVDYDETSISERETDDIAECFPHSDQP
CCHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCC
GVRWLDMEGIHRPELLKTLGECYGIHPLTLEDILNTDQRPKLEDFDDYLFVVLKMLSLQP
CCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
DGSLTAEQVSFVLGPSFLISFQEGFKGDLFDSIRRRLRENRGKLRKSGSDFLLYSLMDAI
CCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VDYYFVILEDLAERIEELEEEVIAGPSRKTVVKIQHLKRETIFLRKSVWPLREVLGRLER
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESPLVRGETVIYLRDVYDHCIQIIETVETFRDLLSEILDIYLSAIGNRTNEVMKVLTII
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ATIFMPLTFIAGVYGMNFRYMPELEWHWGYPAVLLLMLLVSLGMGIFFRRKRWL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCC
>Mature Secondary Structure
MKKIIKQRSRKTGLPPGSLVHIGEQTGEPVRISLVDYDETSISERETDDIAECFPHSDQP
CCHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCC
GVRWLDMEGIHRPELLKTLGECYGIHPLTLEDILNTDQRPKLEDFDDYLFVVLKMLSLQP
CCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
DGSLTAEQVSFVLGPSFLISFQEGFKGDLFDSIRRRLRENRGKLRKSGSDFLLYSLMDAI
CCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VDYYFVILEDLAERIEELEEEVIAGPSRKTVVKIQHLKRETIFLRKSVWPLREVLGRLER
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESPLVRGETVIYLRDVYDHCIQIIETVETFRDLLSEILDIYLSAIGNRTNEVMKVLTII
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ATIFMPLTFIAGVYGMNFRYMPELEWHWGYPAVLLLMLLVSLGMGIFFRRKRWL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]