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The map label for this gene is cdsA [H]

Identifier: 38234083

GI number: 38234083

Start: 1528307

End: 1529185

Strand: Reverse

Name: cdsA [H]

Synonym: DIP1504

Alternate gene names: 38234083

Gene position: 1529185-1528307 (Counterclockwise)

Preceding gene: 38234084

Following gene: 38234081

Centisome position: 61.45

GC content: 48.81

Gene sequence:

>879_bases
ATGCCTCATTCATCAACGGCTTTTGAGCACTTGCCTAAACCGAAGAATTCGGCTGGTCGAAACCTGAAAGCCGCGATCAG
CGTTGGAATTGGCTTGGGCGCCCTCGTATTGCTCGCTATCTTTGTTATTCCTTTTGGTTGGTATCCATTAGTGGCTATCG
CAATCGCAGTGGCAACTTGGGAGGTAGAGCGCCGTTTAATAGAAGCCGGTTATCTTTTGCAACGTTGGGTCATGCTTATT
GGCGGACAAGTCATGTTGTGGCTTAGTTGGCCATTTGGTCCGAAGGGATTAGTGGCTGGTTTCGTCGGCGTTGTACTCGC
TACGATGTTTGGTCGGCTTTTCCATCATGGTCGTTCTATGCCACCGAAAAACTATCTGCGAGATACTGCCGTCGCAATTT
TTGTTTTAACGTGGATCCCACTTTTTGGTAGTTTTGCGGCAATGCTTTCGCTGTTTGAAACAGAAACAGCACCCGGAAAG
TACTTCATCGTCACATTCATGTTGTGCGTTATCGCCTCTGACGTAGGCGGTTATATTGCAGGCGTGATGTTCGGATCGCA
CCCCATGGCACCTGCGGTAAGCCCAAAGAAATCGTGGGAGGGCTTTATCGGTTCTGTAGTCTTTGGCATGATTGTTGGAG
CATTCACTGTGTCCTATTTATTAGGGCATCAATGGTGGTGGGGATTAGTTCTCGGATTTGGACTTGTGATCTGCGCGACA
CTGGGCGATCTTGTCGAATCCCAGTTTAAGAGGGAACTCGGGATCAAAGACATGTCTGCGATTTTGCCCGGCCATGGTGG
TCTGATGGATCGGCTTGACGGTATGTTGCCATCGGCTATGGTGACATGGTTAGTCTTGAGTGTGATTTCTTCAGTATAG

Upstream 100 bases:

>100_bases
ACAACGAAACACACTTCATCCGTTGGGTTTTGGGGCAGACGCTGCACAGGCAGGATCTGCCCCTTTTCCCGCATCTTAAC
ACCAAGGAGAGCGCCGACCG

Downstream 100 bases:

>100_bases
AAAATAAAAGCGCAACCGGCCCCTAATCTGTAGGAGGCCGGTTCCGCTTTTATCTAAGTTGGTTAAATCGAACGCTGTAA
GTTTTTAATTTGTCGACGTA

Product: putative phospholipid biosynthesis

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPHSSTAFEHLPKPKNSAGRNLKAAISVGIGLGALVLLAIFVIPFGWYPLVAIAIAVATWEVERRLIEAGYLLQRWVMLI
GGQVMLWLSWPFGPKGLVAGFVGVVLATMFGRLFHHGRSMPPKNYLRDTAVAIFVLTWIPLFGSFAAMLSLFETETAPGK
YFIVTFMLCVIASDVGGYIAGVMFGSHPMAPAVSPKKSWEGFIGSVVFGMIVGAFTVSYLLGHQWWWGLVLGFGLVICAT
LGDLVESQFKRELGIKDMSAILPGHGGLMDRLDGMLPSAMVTWLVLSVISSV

Sequences:

>Translated_292_residues
MPHSSTAFEHLPKPKNSAGRNLKAAISVGIGLGALVLLAIFVIPFGWYPLVAIAIAVATWEVERRLIEAGYLLQRWVMLI
GGQVMLWLSWPFGPKGLVAGFVGVVLATMFGRLFHHGRSMPPKNYLRDTAVAIFVLTWIPLFGSFAAMLSLFETETAPGK
YFIVTFMLCVIASDVGGYIAGVMFGSHPMAPAVSPKKSWEGFIGSVVFGMIVGAFTVSYLLGHQWWWGLVLGFGLVICAT
LGDLVESQFKRELGIKDMSAILPGHGGLMDRLDGMLPSAMVTWLVLSVISSV
>Mature_291_residues
PHSSTAFEHLPKPKNSAGRNLKAAISVGIGLGALVLLAIFVIPFGWYPLVAIAIAVATWEVERRLIEAGYLLQRWVMLIG
GQVMLWLSWPFGPKGLVAGFVGVVLATMFGRLFHHGRSMPPKNYLRDTAVAIFVLTWIPLFGSFAAMLSLFETETAPGKY
FIVTFMLCVIASDVGGYIAGVMFGSHPMAPAVSPKKSWEGFIGSVVFGMIVGAFTVSYLLGHQWWWGLVLGFGLVICATL
GDLVESQFKRELGIKDMSAILPGHGGLMDRLDGMLPSAMVTWLVLSVISSV

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=173, Percent_Identity=36.9942196531792, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787677, Length=110, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31633; Mature: 31502

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHSSTAFEHLPKPKNSAGRNLKAAISVGIGLGALVLLAIFVIPFGWYPLVAIAIAVATW
CCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EVERRLIEAGYLLQRWVMLIGGQVMLWLSWPFGPKGLVAGFVGVVLATMFGRLFHHGRSM
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PPKNYLRDTAVAIFVLTWIPLFGSFAAMLSLFETETAPGKYFIVTFMLCVIASDVGGYIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GVMFGSHPMAPAVSPKKSWEGFIGSVVFGMIVGAFTVSYLLGHQWWWGLVLGFGLVICAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDLVESQFKRELGIKDMSAILPGHGGLMDRLDGMLPSAMVTWLVLSVISSV
HHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]