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The map label for this gene is frr

Identifier: 38234084

GI number: 38234084

Start: 1529309

End: 1529866

Strand: Reverse

Name: frr

Synonym: DIP1505

Alternate gene names: 38234084

Gene position: 1529866-1529309 (Counterclockwise)

Preceding gene: 38234085

Following gene: 38234083

Centisome position: 61.47

GC content: 47.49

Gene sequence:

>558_bases
ATGATCGATGAGATCCTGTTTGAAGCTGAAGAGCACATGAACACTTCGGTGGAACGTACCCGTGACGAGCTGGTCAATAT
CCGTACCGGTCGTGCAAACCCTGCAATGTTTAATGGAGTAATTGCCGATTACTACGGGGTACCAACTCCAATTACGCAGA
TGGCCACCATTTCTGTCCCAGAGGCTCGTATGCTGCTGATTAAGCCTTACGAGATGTCGATGATGAACGAAATTGAGAAT
GCGATCCGTAATTCGGATTTGGGAGTTAACCCAACTAATGATGGCCAAGTTCTCCGTGTTACCATCCCACAGCTGACAGA
AGAGCGTCGTCGTGACATGGCTAAACTCGCAAAGTCTAAGGGCGAAGACGGTAAGATCGCCATCCGGAATGTTCGTCGCA
AAGGCATGGATCAGCTCAAGAAGATTCAAAAAGATGGCGATGCTGGCGAGGATGAAGTTCAGGCTGCTGAAAAGGAGCTT
GATAAAGTTACCGCTAAGTATGTAGCTCAGGTTGATGAGGTTGTTGCTAAGAAGGAAGCAGAACTAATGGAGGTTTAA

Upstream 100 bases:

>100_bases
AACAAATCGGTACTTTGGTTCAATCCTGATAGATTAAGTGTGATCGAACGCTGCTATTGAGTGTTCCTTGACTTACCTAA
AAACTGCAAAGGACAACATA

Downstream 100 bases:

>100_bases
GTCCTCCTCGTTTCAGCTAAGCAACAACGAAACACACTTCATCCGTTGGGTTTTGGGGCAGACGCTGCACAGGCAGGATC
TGCCCCTTTTCCCGCATCTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDEILFEAEEHMNTSVERTRDELVNIRTGRANPAMFNGVIADYYGVPTPITQMATISVPEARMLLIKPYEMSMMNEIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMAKLAKSKGEDGKIAIRNVRRKGMDQLKKIQKDGDAGEDEVQAAEKEL
DKVTAKYVAQVDEVVAKKEAELMEV

Sequences:

>Translated_185_residues
MIDEILFEAEEHMNTSVERTRDELVNIRTGRANPAMFNGVIADYYGVPTPITQMATISVPEARMLLIKPYEMSMMNEIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMAKLAKSKGEDGKIAIRNVRRKGMDQLKKIQKDGDAGEDEVQAAEKEL
DKVTAKYVAQVDEVVAKKEAELMEV
>Mature_185_residues
MIDEILFEAEEHMNTSVERTRDELVNIRTGRANPAMFNGVIADYYGVPTPITQMATISVPEARMLLIKPYEMSMMNEIEN
AIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMAKLAKSKGEDGKIAIRNVRRKGMDQLKKIQKDGDAGEDEVQAAEKEL
DKVTAKYVAQVDEVVAKKEAELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=185, Percent_Identity=30.8108108108108, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI291042689, Length=137, Percent_Identity=33.5766423357664, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=39.6739130434783, Blast_Score=157, Evalue=5e-40,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CORDI (P61303)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939851.1
- ProteinModelPortal:   P61303
- SMR:   P61303
- GeneID:   2650389
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1505
- NMPDR:   fig|257309.1.peg.1442
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   P61303
- ProtClustDB:   PRK00083
- BioCyc:   CDIP257309:DIP1505-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20823; Mature: 20823

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEILFEAEEHMNTSVERTRDELVNIRTGRANPAMFNGVIADYYGVPTPITQMATISVP
CCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCC
EARMLLIKPYEMSMMNEIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMAKLAKSK
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNVRRKGMDQLKKIQKDGDAGEDEVQAAEKELDKVTAKYVAQVDEVVAKKEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIDEILFEAEEHMNTSVERTRDELVNIRTGRANPAMFNGVIADYYGVPTPITQMATISVP
CCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCC
EARMLLIKPYEMSMMNEIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMAKLAKSK
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCC
GEDGKIAIRNVRRKGMDQLKKIQKDGDAGEDEVQAAEKELDKVTAKYVAQVDEVVAKKEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910