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The map label for this gene is yciC [H]

Identifier: 38234067

GI number: 38234067

Start: 1507395

End: 1508519

Strand: Reverse

Name: yciC [H]

Synonym: DIP1486

Alternate gene names: 38234067

Gene position: 1508519-1507395 (Counterclockwise)

Preceding gene: 38234068

Following gene: 38234065

Centisome position: 60.62

GC content: 51.38

Gene sequence:

>1125_bases
ATGTCGCATTCAACTCCCGTCACCGTCTTGTCTGGTTTCCTAGGGTCAGGAAAAACCACGCTTCTCAACCAAATGCTGTC
CAACCGCGAATCCAAAAAAATAGCGGTCATTGTCAATGACTTTTCAGAAATCAACATTGATGCAGCTCTCATCGCAGGTG
AAGGGCATCTCGAACGCGGCGAAGACAAATTTGTTGAACTAACCAACGGCTGCATTTGCTGCACGCTTCGCGACGACCTC
GTCCAGTCCGTCGGCGCACTAGCATCAAGCGGCGACTACGATCACATCGTGATTGAATCAACGGGCATATCCGAACCAAT
GCCGGTTGCCGCCACCTTCGAATGGGTATGGGACGATGGAACTCGCCTAGCCGACATTGCACCGATCGACACGATGGCAA
CTCTTGTTGACGCTTCTCAGTTCCTGACCTACATGGGCAAGAAAACCTACCTCACTGACCGTGATCTAGGTGTAACCGAA
GACGACGAACGAACAATTGCTGATTTGCTCGTTGATCAAGTGGAATTCGCTGACAAGATTTACATCACCAAATCAGACCT
CGTCGATGACGAGCGATACCATGCCACCAAAGCACTCGTGCGTCGTATGAATCCCCGCGCAAGTATCGACAAACTTGTCA
ACGGTCGAGTCATCACTGCCAGCGGTGAAAACCGAAATGCCATTAATGACCTCCTCGGAGCCATGTGCTACGACGAAGAA
ACTGCGCGGACCTATCAAGGGTATGTTGCAGAACTAGATAATCCACACACCCCAGAAACTGAGGAATACGGAATTAGCTC
TTTCGTATTCAAAGGAGATCGTCCCTTTGACCGGCAGCGCCTCATAGCCGCCTTACGCTCAACTCGTGGCATCGTGCGTT
CCAAAGGACACTGCTGGATTTCCGACCGCATCGATATGGTACAGGTATGGCACCAAGCCGGACCTGACCTACGGATTGCG
CCTGCAGGCTACTGGCAATCAGCCGGAATTACACCCTCAAACGAAATTGTCGTCATTGGCGTAAATTTTGATCACGCTCA
AGCCCAGCAACTTCTCAATGACGCCATGCTCAGCGATTCCGAAGTACAACAACTGCTGAGCACCGCCGATGCAGCCAAGA
GCTAG

Upstream 100 bases:

>100_bases
GATGGTTCTTACGGTGGATTTCGCTATGGTCTTGCCGTTAAGCGTTCGTTGTTAACGCGAGAAGTTGCACATAATAAGTG
AAAACGGTATCCATTAAGGA

Downstream 100 bases:

>100_bases
CGCCTAAGTGCCACAATAAGTCACATAATCCTGCCACGTTTCAGGGGCAGGATTCTCCAATTTTTCAAATCGCTTCTCTC
GAAGATAAGGGTTTTTCCCA

Product: putative cobalamin synthesis-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERGEDKFVELTNGCICCTLRDDL
VQSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDGTRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGVTE
DDERTIADLLVDQVEFADKIYITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEE
TARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWISDRIDMVQVWHQAGPDLRIA
PAGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDSEVQQLLSTADAAKS

Sequences:

>Translated_374_residues
MSHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERGEDKFVELTNGCICCTLRDDL
VQSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDGTRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGVTE
DDERTIADLLVDQVEFADKIYITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEE
TARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWISDRIDMVQVWHQAGPDLRIA
PAGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDSEVQQLLSTADAAKS
>Mature_373_residues
SHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERGEDKFVELTNGCICCTLRDDLV
QSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDGTRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGVTED
DERTIADLLVDQVEFADKIYITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEET
ARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWISDRIDMVQVWHQAGPDLRIAP
AGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDSEVQQLLSTADAAKS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=232, Percent_Identity=32.3275862068966, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI126722884, Length=232, Percent_Identity=31.8965517241379, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI223941779, Length=208, Percent_Identity=33.1730769230769, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI146231952, Length=380, Percent_Identity=27.8947368421053, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI148727351, Length=380, Percent_Identity=27.6315789473684, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI223941776, Length=223, Percent_Identity=30.9417040358744, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI119120938, Length=144, Percent_Identity=35.4166666666667, Blast_Score=95, Evalue=8e-20,
Organism=Escherichia coli, GI87082430, Length=305, Percent_Identity=29.1803278688525, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788499, Length=103, Percent_Identity=36.8932038834951, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=215, Percent_Identity=31.1627906976744, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41184; Mature: 41052

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERG
CCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCC
EDKFVELTNGCICCTLRDDLVQSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDG
CCHHEEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC
TRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGVTEDDERTIADLLVDQVEFADKI
CEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCEE
YITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEE
EEEHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHH
TARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWI
HHHHHHHHHHCCCCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
SDRIDMVQVWHQAGPDLRIAPAGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDS
CCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHH
EVQQLLSTADAAKS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERG
CCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCC
EDKFVELTNGCICCTLRDDLVQSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDG
CCHHEEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC
TRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGVTEDDERTIADLLVDQVEFADKI
CEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCEE
YITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEE
EEEHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHH
TARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWI
HHHHHHHHHHCCCCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
SDRIDMVQVWHQAGPDLRIAPAGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDS
CCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHH
EVQQLLSTADAAKS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]