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The map label for this gene is ribF [H]

Identifier: 38234051

GI number: 38234051

Start: 1490204

End: 1491175

Strand: Reverse

Name: ribF [H]

Synonym: DIP1470

Alternate gene names: 38234051

Gene position: 1491175-1490204 (Counterclockwise)

Preceding gene: 38234053

Following gene: 38234050

Centisome position: 59.92

GC content: 49.59

Gene sequence:

>972_bases
GTGGATCAGGTGGACATTTGGCACAGATTAGAAGATATTCCAGCAGACTTGAAAGCCTCAGTTATCACCATTGGCGTATT
CGATGGTGTTCACCGTGGTCACCGAACCCTTGTAGCAGCAGCGACTGATCGAGCACAAGCATTGGGAGTTCCTAGTGTGC
TCGTGACGTTTAACCCGCATCCGTTGTCGGTCCTGCGACCTGACAAGATGCCTCCATTGCTGGGAACGGTAAATCAGCGA
GCAGATTTAGCAGAATCTTTAGGCGTTGATCACATGTTCGCTATGAATTTCACTGCGGAACTCTCGCACTTGTCGCCTGA
AGAATTCTTCTGTTCTGTGATCAAAGACAAACTCAATGCTCAAGCAATAGTAGTAGGAAAGAATTTTACTTTCGGGTACA
AAGCTGCGGGTACGACAGACACTCTGAAAGCATTAGGGGAGAAGTACGGAGTCGAGATCTACGTACTGGATCTACTGACG
GAAAATGGTGATGTAGTGTCCTCCACCGCTATTCGATCGGATTTGCTGGAGGGGGATATTCGCCGTGCGAACTGGGGCCT
TGGCCGTGAATTCTCTGTCCACGGCGATGTTGTGCGTGGAGCCGGTCGTGGGGGCAAAGAACTCGGTTTTCCAACTGCCA
ACCTTTATTTTCCTGATAGTATCGCGTTGCCAGAAGACGGCGTCTATGCAGGTTGGCTCACTGTTACTTCTTCGGCGCCC
ATTGATGGCGACATGGTGCGTGGGGTGCGGTATCCGGCTGCAATTTCAGTCGGACACAATCCTACGTTCGGCGATAAGCG
TCGCAGCGTAGAGTCATTTGTACTCGACCGCCATGCCGATCTTTATGGGCATTCCATAGTCGTAGAGTTCGTTGATCGGA
TTCGTCCGATGGTCAAATTTGATGGCATTGATGAGTTGCTTGTTGCTATTGAAAATGATGTAACTCAAACGCGTGCCATA
TTGCATATCTAA

Upstream 100 bases:

>100_bases
AGAAACAACGTCGTGGGAGGTCATTCCTTGGGGTTTGTCGACAATCACAAGGCCTGAGTCTGCGAGGGCATCATTCATAG
ATGACAGTCTATGGCTTAAA

Downstream 100 bases:

>100_bases
ATCCATCCCCTCCGAACGCAGCTAAAGGACCGTCGAGATGAAAAAAATTATCCTTGATTTGGACACTGGTATCGATGATG
CTCTGGCATTGGCCTATACG

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPHPLSVLRPDKMPPLLGTVNQR
ADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNAQAIVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLT
ENGDVVSSTAIRSDLLEGDIRRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAP
IDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKFDGIDELLVAIENDVTQTRAI
LHI

Sequences:

>Translated_323_residues
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPHPLSVLRPDKMPPLLGTVNQR
ADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNAQAIVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLT
ENGDVVSSTAIRSDLLEGDIRRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAP
IDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKFDGIDELLVAIENDVTQTRAI
LHI
>Mature_323_residues
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPHPLSVLRPDKMPPLLGTVNQR
ADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNAQAIVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLT
ENGDVVSSTAIRSDLLEGDIRRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAP
IDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKFDGIDELLVAIENDVTQTRAI
LHI

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=139, Percent_Identity=35.2517985611511, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1786208, Length=318, Percent_Identity=30.5031446540881, Blast_Score=150, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17541882, Length=132, Percent_Identity=37.8787878787879, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644927, Length=131, Percent_Identity=38.1679389312977, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 35218; Mature: 35218

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPH
CCCHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCHHHCCCCEEEEEECCC
PLSVLRPDKMPPLLGTVNQRADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNA
CCEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHCCC
QAIVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLTENGDVVSSTAIRSDLLEGDI
EEEEEECCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEEECCCCEEEHHHHHHHHHHCCH
RRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAP
HHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCC
IDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKF
CCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEE
DGIDELLVAIENDVTQTRAILHI
CCHHHHHHHHHCCHHHHEEEECC
>Mature Secondary Structure
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPH
CCCHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCHHHCCCCEEEEEECCC
PLSVLRPDKMPPLLGTVNQRADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNA
CCEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHCCC
QAIVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLTENGDVVSSTAIRSDLLEGDI
EEEEEECCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEEECCCCEEEHHHHHHHHHHCCH
RRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAP
HHCCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCC
IDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKF
CCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEE
DGIDELLVAIENDVTQTRAILHI
CCHHHHHHHHHCCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]