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The map label for this gene is yqhT [H]

Identifier: 38233927

GI number: 38233927

Start: 1354148

End: 1355245

Strand: Reverse

Name: yqhT [H]

Synonym: DIP1341

Alternate gene names: 38233927

Gene position: 1355245-1354148 (Counterclockwise)

Preceding gene: 38233928

Following gene: 38233926

Centisome position: 54.46

GC content: 46.99

Gene sequence:

>1098_bases
ATGACTATGCCATTGGCTGATACTCGTTTTTTACAGCGCCGACGTGCTCTTTCTGCACAGCTTGCAGCCAAGCGTATCGA
CGCCATGTTAGTGACGCATTTGACGCATATTCGCTATTTATCGGGATTTACCGGTTCAAATGCGGCACTAATCATCAATA
AGGATCTTTCGGCGCGTATTTCAACAGACGGCCGATACATCACACAGATTGCTGAGCAAGTACCAGATATTGAATCTTTA
ATGGCTCGCAATTGTGCTCCAGCTCTTCTATCGGACATTAATGGTCCGAAGCGGGTCGGATTTGAGGCGGACTATCTATC
AGTTTCGCAATGCGAAGAATTGCGTAAATCAGCAGGCTCCGATGTGGAGTTGATTCCAGTGACTGGAGCCATCGAGAAGC
TTCGGCTAATAAAAGACTCATTGGAAATTGAGTCTCTTCGATCTGTAGCAAAAATTGCAAATACTGCTTTTCAGGAACTT
ATCGATGATGGCTTGATTGCTGCAGGGCGAACTGAACGTGCGATAGCCGCCGATTTGGAGTATCGGATGCGCATTAAAGG
TGCAGAACGGCCGAGTTTTGACACCATCGTGGCATCGGGTCCAAATTCGGCAAAACCACACCATGGTGCCGGTGATCGGG
TGATATGTGAAGGGGATATCGTCACTATAGATTTTGGTGCATATGCTGATGGTTATAACTCAGATACGACTCGAACCGTG
ATCGTTGGGCAACCAACTGCATTTGCTCGAGAAATCTACTCGATAGTTTTAGAAGCTCAGCGTGCGGGTTGTGCTGCTGC
TGTGCCAGGTACTTCATTGGTAGACGTCGATAAGGCTTGTCGCGAAGTCATTGAGAATGCTGGATATGGTGAATATTTTG
TTCACTCAACTGGTCACGGTCTGGGTTTGGACGTTCACGAACAGCCTGCAGCGGCTGTGACTGGAAGCGGAGTTTTGGAA
GAAAACATGACTCTCACTATCGAACCTGGAATTTATGTCCCAGGTAAAGGTGGAGTACGAATCGAAGATTCACTCGTTAT
TCGTAGCGGATCGGCTGAAAACCTCACGAGTCTTTCCAAGGATCTTTTGATATTCTAA

Upstream 100 bases:

>100_bases
GGAGTTATCGCCGGACTGGGAACAATCGGTTACGAATTAGCTCTCCGATATGTAGTTTCGACTTTAAACTCATAAAAAAC
TCTCATCGATGTAGGAGAAT

Downstream 100 bases:

>100_bases
AGTGTCGAAGCGAAATTGATAATATTGCTAAAGCTTTAGTGTAGTATTGACTGGCTACCGACAGCATCAAATCTTTTCAT
CGAAAGAAAGAAGTATTCAG

Product: putative metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTMPLADTRFLQRRRALSAQLAAKRIDAMLVTHLTHIRYLSGFTGSNAALIINKDLSARISTDGRYITQIAEQVPDIESL
MARNCAPALLSDINGPKRVGFEADYLSVSQCEELRKSAGSDVELIPVTGAIEKLRLIKDSLEIESLRSVAKIANTAFQEL
IDDGLIAAGRTERAIAADLEYRMRIKGAERPSFDTIVASGPNSAKPHHGAGDRVICEGDIVTIDFGAYADGYNSDTTRTV
IVGQPTAFAREIYSIVLEAQRAGCAAAVPGTSLVDVDKACREVIENAGYGEYFVHSTGHGLGLDVHEQPAAAVTGSGVLE
ENMTLTIEPGIYVPGKGGVRIEDSLVIRSGSAENLTSLSKDLLIF

Sequences:

>Translated_365_residues
MTMPLADTRFLQRRRALSAQLAAKRIDAMLVTHLTHIRYLSGFTGSNAALIINKDLSARISTDGRYITQIAEQVPDIESL
MARNCAPALLSDINGPKRVGFEADYLSVSQCEELRKSAGSDVELIPVTGAIEKLRLIKDSLEIESLRSVAKIANTAFQEL
IDDGLIAAGRTERAIAADLEYRMRIKGAERPSFDTIVASGPNSAKPHHGAGDRVICEGDIVTIDFGAYADGYNSDTTRTV
IVGQPTAFAREIYSIVLEAQRAGCAAAVPGTSLVDVDKACREVIENAGYGEYFVHSTGHGLGLDVHEQPAAAVTGSGVLE
ENMTLTIEPGIYVPGKGGVRIEDSLVIRSGSAENLTSLSKDLLIF
>Mature_364_residues
TMPLADTRFLQRRRALSAQLAAKRIDAMLVTHLTHIRYLSGFTGSNAALIINKDLSARISTDGRYITQIAEQVPDIESLM
ARNCAPALLSDINGPKRVGFEADYLSVSQCEELRKSAGSDVELIPVTGAIEKLRLIKDSLEIESLRSVAKIANTAFQELI
DDGLIAAGRTERAIAADLEYRMRIKGAERPSFDTIVASGPNSAKPHHGAGDRVICEGDIVTIDFGAYADGYNSDTTRTVI
VGQPTAFAREIYSIVLEAQRAGCAAAVPGTSLVDVDKACREVIENAGYGEYFVHSTGHGLGLDVHEQPAAAVTGSGVLEE
NMTLTIEPGIYVPGKGGVRIEDSLVIRSGSAENLTSLSKDLLIF

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=254, Percent_Identity=33.4645669291339, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI264681563, Length=274, Percent_Identity=31.021897810219, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI93141226, Length=199, Percent_Identity=34.1708542713568, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI264681565, Length=270, Percent_Identity=30, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI149589008, Length=293, Percent_Identity=26.962457337884, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI260593665, Length=293, Percent_Identity=26.962457337884, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=36.7688022284123, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789275, Length=287, Percent_Identity=31.7073170731707, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786364, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508215, Length=314, Percent_Identity=28.343949044586, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=167, Percent_Identity=35.9281437125749, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320922, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6321118, Length=291, Percent_Identity=27.4914089347079, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19920384, Length=276, Percent_Identity=29.3478260869565, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357079, Length=296, Percent_Identity=27.3648648648649, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137632, Length=180, Percent_Identity=34.4444444444444, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39134; Mature: 39003

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPLADTRFLQRRRALSAQLAAKRIDAMLVTHLTHIRYLSGFTGSNAALIINKDLSARI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEE
STDGRYITQIAEQVPDIESLMARNCAPALLSDINGPKRVGFEADYLSVSQCEELRKSAGS
CCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHCCC
DVELIPVTGAIEKLRLIKDSLEIESLRSVAKIANTAFQELIDDGLIAAGRTERAIAADLE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCE
YRMRIKGAERPSFDTIVASGPNSAKPHHGAGDRVICEGDIVTIDFGAYADGYNSDTTRTV
EEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCEEEE
IVGQPTAFAREIYSIVLEAQRAGCAAAVPGTSLVDVDKACREVIENAGYGEYFVHSTGHG
EEECCHHHHHHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCC
LGLDVHEQPAAAVTGSGVLEENMTLTIEPGIYVPGKGGVRIEDSLVIRSGSAENLTSLSK
CCCCCCCCCCCEECCCCEEECCCEEEECCCEEECCCCCEEEECEEEEECCCCHHHHHHHH
DLLIF
HHCCC
>Mature Secondary Structure 
TMPLADTRFLQRRRALSAQLAAKRIDAMLVTHLTHIRYLSGFTGSNAALIINKDLSARI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEE
STDGRYITQIAEQVPDIESLMARNCAPALLSDINGPKRVGFEADYLSVSQCEELRKSAGS
CCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHCCC
DVELIPVTGAIEKLRLIKDSLEIESLRSVAKIANTAFQELIDDGLIAAGRTERAIAADLE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCE
YRMRIKGAERPSFDTIVASGPNSAKPHHGAGDRVICEGDIVTIDFGAYADGYNSDTTRTV
EEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCEEEE
IVGQPTAFAREIYSIVLEAQRAGCAAAVPGTSLVDVDKACREVIENAGYGEYFVHSTGHG
EEECCHHHHHHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCC
LGLDVHEQPAAAVTGSGVLEENMTLTIEPGIYVPGKGGVRIEDSLVIRSGSAENLTSLSK
CCCCCCCCCCCEECCCCEEECCCEEEECCCEEECCCCCEEEECEEEEECCCCHHHHHHHH
DLLIF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]