Click here to switch to the map view.

The map label for this gene is efp

Identifier: 38233926

GI number: 38233926

Start: 1353483

End: 1354046

Strand: Reverse

Name: efp

Synonym: DIP1340

Alternate gene names: 38233926

Gene position: 1354046-1353483 (Counterclockwise)

Preceding gene: 38233927

Following gene: 38233925

Centisome position: 54.41

GC content: 50.35

Gene sequence:

>564_bases
GTGGCAACTACTGCCGATTTTAAGAACGGTCTTGTCCTCAAGATTGACAACAAGCTCCAGCAGATTATTGAGTTCCAGCA
CGTCAAGCCTGGTAAAGGTCCTGCATTCGTGCGTACAAAGCTGAAGGATGTTGTCTCCGGAAAAGTCACCGATAAAACCT
TTAACGCTGGTGTCAAGGTTGAAACGGCAACCGTTGATCGCCGTGATATGACTTACCTGTACAACGATGGATCTTCCTAC
GTTGTCATGGATGAAAAGACCTTTGAACAGGCGGAGCTGGCTCCTCACATCTTCGGTGATGCTGCTCGTTTCCTTCTAGA
GAACACCACTGTTCAGGTATCTTTCCACGAGGGTGAGCCTTTGTTTGCTGAACTGCCAATCTCTCTCGACCTTCGCATCG
AGCACACCGATCCCGGCCTTCAGGGCGATCGTTCCACTGGCGGTACGAAGCCAGCAACTCTTGAGACTGGTGCCGAGATT
CAGGTCCCACTGTTCATCGAGACTGGAAATGTGGTTAAGGTGGATACCCGCGACGGTTCCTACCTATCTCGCGTAAACAA
CTAA

Upstream 100 bases:

>100_bases
GTGTCGAAGCGAAATTGATAATATTGCTAAAGCTTTAGTGTAGTATTGACTGGCTACCGACAGCATCAAATCTTTTCATC
GAAAGAAAGAAGTATTCAGC

Downstream 100 bases:

>100_bases
TTGTGAGCGGTAACAAAGTGAACCCTGAAGATGAAAATACCTCTCAGACGAAAAAACCGGCTGAGGAATTGAAGTCTCAA
GAGACTAGGTCTTCTTGGAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MATTADFKNGLVLKIDNKLQQIIEFQHVKPGKGPAFVRTKLKDVVSGKVTDKTFNAGVKVETATVDRRDMTYLYNDGSSY
VVMDEKTFEQAELAPHIFGDAARFLLENTTVQVSFHEGEPLFAELPISLDLRIEHTDPGLQGDRSTGGTKPATLETGAEI
QVPLFIETGNVVKVDTRDGSYLSRVNN

Sequences:

>Translated_187_residues
MATTADFKNGLVLKIDNKLQQIIEFQHVKPGKGPAFVRTKLKDVVSGKVTDKTFNAGVKVETATVDRRDMTYLYNDGSSY
VVMDEKTFEQAELAPHIFGDAARFLLENTTVQVSFHEGEPLFAELPISLDLRIEHTDPGLQGDRSTGGTKPATLETGAEI
QVPLFIETGNVVKVDTRDGSYLSRVNN
>Mature_186_residues
ATTADFKNGLVLKIDNKLQQIIEFQHVKPGKGPAFVRTKLKDVVSGKVTDKTFNAGVKVETATVDRRDMTYLYNDGSSYV
VMDEKTFEQAELAPHIFGDAARFLLENTTVQVSFHEGEPLFAELPISLDLRIEHTDPGLQGDRSTGGTKPATLETGAEIQ
VPLFIETGNVVKVDTRDGSYLSRVNN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=187, Percent_Identity=43.3155080213904, Blast_Score=153, Evalue=6e-39,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_CORDI (Q6NH07)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939693.1
- ProteinModelPortal:   Q6NH07
- SMR:   Q6NH07
- GeneID:   2648783
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1340
- NMPDR:   fig|257309.1.peg.1284
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q6NH07
- ProtClustDB:   PRK00529
- BioCyc:   CDIP257309:DIP1340-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20602; Mature: 20471

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTADFKNGLVLKIDNKLQQIIEFQHVKPGKGPAFVRTKLKDVVSGKVTDKTFNAGVKV
CCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCEEE
ETATVDRRDMTYLYNDGSSYVVMDEKTFEQAELAPHIFGDAARFLLENTTVQVSFHEGEP
EEEECCCCCEEEEEECCCEEEEEECCCCCHHHCCCHHHHHHHHHEEECCEEEEEEECCCC
LFAELPISLDLRIEHTDPGLQGDRSTGGTKPATLETGAEIQVPLFIETGNVVKVDTRDGS
EEEECCEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCH
YLSRVNN
HHHCCCC
>Mature Secondary Structure 
ATTADFKNGLVLKIDNKLQQIIEFQHVKPGKGPAFVRTKLKDVVSGKVTDKTFNAGVKV
CCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCEEE
ETATVDRRDMTYLYNDGSSYVVMDEKTFEQAELAPHIFGDAARFLLENTTVQVSFHEGEP
EEEECCCCCEEEEEECCCEEEEEECCCCCHHHCCCHHHHHHHHHEEECCEEEEEEECCCC
LFAELPISLDLRIEHTDPGLQGDRSTGGTKPATLETGAEIQVPLFIETGNVVKVDTRDGS
EEEECCEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCH
YLSRVNN
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910