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The map label for this gene is gap [H]

Identifier: 38233896

GI number: 38233896

Start: 1321111

End: 1322115

Strand: Reverse

Name: gap [H]

Synonym: DIP1310

Alternate gene names: 38233896

Gene position: 1322115-1321111 (Counterclockwise)

Preceding gene: 38233897

Following gene: 38233895

Centisome position: 53.13

GC content: 50.25

Gene sequence:

>1005_bases
GTGACGATTCGCGTAGGTATCAATGGTTTTGGCCGTATTGGTCGTAACTTCTACCGTGCAATTACTGAGCGCGGTGCTGA
CATCGAGGTTGTTGCAATCAACGACCTGACTGATAACCACACTCTTTCACATCTATTGAAGTATGACTCCATCCTTGGTC
GTTTGGGCAAGGAAGTCAGCTACGATGATGAATCCATCACCGTCGATGGCCATCGCATGGTTGTCACCGCTGAGCGCGAT
CCTAAGAACCTTAAGTGGGGCGAGCTGAACGTTGACATCGTTGTCGAGTCGACTGGCTTCTTTACTGATGCTAATGCTGC
GAAGGCTCATATTGAGGCTGGCGCAAAGAAGGTCATCATTTCTGCACCTGCAAAGAATGAGGATGCAACTTTCGTTGTTG
GTGTTAACCACACCGACTACGATCCCGCTAAGCACAACATCATCTCAAACGCTTCCTGCACGACCAACTGCTTGGCTCCA
ATGGCTAAGGTATTGGACGAGAAGTTCGGTATCGTCAAGGGCTTGATGACCACCATCCACGCTTACACTGGTGATCAGCG
TCTCCACGATGCACCACACCGCGATCTTCGCCGTGCACGCGCCGCAGCTCAGAACATTGTTCCTACTTCCACTGGTGCAG
CTAAGGCAGTAGCCTTGGTTCTTCCAGAACTGAAGGGTAAGCTCGACGGTTTCGCAATGCGTGTTCCAGTAATCACTGGT
TCTGCAACGGATTTGACCTTCGAAACCACAAAGGAAGTTTCCGCAGAAGAAATTAATGCGGCAATGAAGGAAGCAGCTGA
AGGCGAGCTCAAGGGAGTCTTAGCTTACACCGAGGATCCGATTGTTTCCACCGATATCGTTACCGACGCTCACGCATCGA
TCTTCGATGCTGGCCTAACTAAGGTTATTGGCAACCAAGTTAAGGTTGTTTCTTGGTATGACAACGAGTGGGGTTACTCC
AACCAGCTCGTTTCTCTGACCGAATACGTCGGTGAGCGTCTCTAA

Upstream 100 bases:

>100_bases
AGGGACACCGGAACGAAACAGTCCCGATCGGACAAGATCGGAAAGAATGTTTCGCATTCGGCTTCCAAAAACAATCACTC
AAATGTGAGGAGATATTAAA

Downstream 100 bases:

>100_bases
TTAGGGATCGTAAAGTGCTAATAAAAAGGCGCTAACCCTGCGGCCCGGGGTGTACCTCGAGGTACACCCCGGGCCGTGGT
GCTTATATTCTTCGCAATAC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTIRVGINGFGRIGRNFYRAITERGADIEVVAINDLTDNHTLSHLLKYDSILGRLGKEVSYDDESITVDGHRMVVTAERD
PKNLKWGELNVDIVVESTGFFTDANAAKAHIEAGAKKVIISAPAKNEDATFVVGVNHTDYDPAKHNIISNASCTTNCLAP
MAKVLDEKFGIVKGLMTTIHAYTGDQRLHDAPHRDLRRARAAAQNIVPTSTGAAKAVALVLPELKGKLDGFAMRVPVITG
SATDLTFETTKEVSAEEINAAMKEAAEGELKGVLAYTEDPIVSTDIVTDAHASIFDAGLTKVIGNQVKVVSWYDNEWGYS
NQLVSLTEYVGERL

Sequences:

>Translated_334_residues
MTIRVGINGFGRIGRNFYRAITERGADIEVVAINDLTDNHTLSHLLKYDSILGRLGKEVSYDDESITVDGHRMVVTAERD
PKNLKWGELNVDIVVESTGFFTDANAAKAHIEAGAKKVIISAPAKNEDATFVVGVNHTDYDPAKHNIISNASCTTNCLAP
MAKVLDEKFGIVKGLMTTIHAYTGDQRLHDAPHRDLRRARAAAQNIVPTSTGAAKAVALVLPELKGKLDGFAMRVPVITG
SATDLTFETTKEVSAEEINAAMKEAAEGELKGVLAYTEDPIVSTDIVTDAHASIFDAGLTKVIGNQVKVVSWYDNEWGYS
NQLVSLTEYVGERL
>Mature_333_residues
TIRVGINGFGRIGRNFYRAITERGADIEVVAINDLTDNHTLSHLLKYDSILGRLGKEVSYDDESITVDGHRMVVTAERDP
KNLKWGELNVDIVVESTGFFTDANAAKAHIEAGAKKVIISAPAKNEDATFVVGVNHTDYDPAKHNIISNASCTTNCLAPM
AKVLDEKFGIVKGLMTTIHAYTGDQRLHDAPHRDLRRARAAAQNIVPTSTGAAKAVALVLPELKGKLDGFAMRVPVITGS
ATDLTFETTKEVSAEEINAAMKEAAEGELKGVLAYTEDPIVSTDIVTDAHASIFDAGLTKVIGNQVKVVSWYDNEWGYSN
QLVSLTEYVGERL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=50, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=48.2035928143713, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=53.8922155688623, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=45.619335347432, Blast_Score=289, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=51.7751479289941, Blast_Score=327, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=51.7751479289941, Blast_Score=326, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=51.0385756676558, Blast_Score=319, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=51.0385756676558, Blast_Score=319, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=53.7537537537538, Blast_Score=350, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=52.2522522522522, Blast_Score=339, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=52.5525525525526, Blast_Score=338, Evalue=8e-94,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=48.6486486486487, Blast_Score=310, Evalue=6e-85,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=48.6486486486487, Blast_Score=310, Evalue=6e-85,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=48.048048048048, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=48.048048048048, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=47.2560975609756, Blast_Score=292, Evalue=3e-79,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36212; Mature: 36081

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVGINGFGRIGRNFYRAITERGADIEVVAINDLTDNHTLSHLLKYDSILGRLGKEVS
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDESITVDGHRMVVTAERDPKNLKWGELNVDIVVESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPAKNEDATFVVGVNHTDYDPAKHNIISNASCTTNCLAPMAKVLDEKFGIVKGLMTTIH
ECCCCCCCCEEEEECCCCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYTGDQRLHDAPHRDLRRARAAAQNIVPTSTGAAKAVALVLPELKGKLDGFAMRVPVITG
HHCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEC
SATDLTFETTKEVSAEEINAAMKEAAEGELKGVLAYTEDPIVSTDIVTDAHASIFDAGLT
CCCCEEEHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHEECCCHHHHHHHHHH
KVIGNQVKVVSWYDNEWGYSNQLVSLTEYVGERL
HHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TIRVGINGFGRIGRNFYRAITERGADIEVVAINDLTDNHTLSHLLKYDSILGRLGKEVS
EEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDESITVDGHRMVVTAERDPKNLKWGELNVDIVVESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPAKNEDATFVVGVNHTDYDPAKHNIISNASCTTNCLAPMAKVLDEKFGIVKGLMTTIH
ECCCCCCCCEEEEECCCCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYTGDQRLHDAPHRDLRRARAAAQNIVPTSTGAAKAVALVLPELKGKLDGFAMRVPVITG
HHCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEC
SATDLTFETTKEVSAEEINAAMKEAAEGELKGVLAYTEDPIVSTDIVTDAHASIFDAGLT
CCCCEEEHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHEECCCHHHHHHHHHH
KVIGNQVKVVSWYDNEWGYSNQLVSLTEYVGERL
HHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400158; 12948626 [H]