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The map label for this gene is argK [C]

Identifier: 38233856

GI number: 38233856

Start: 1276921

End: 1277925

Strand: Reverse

Name: argK [C]

Synonym: DIP1271

Alternate gene names: 38233856

Gene position: 1277925-1276921 (Counterclockwise)

Preceding gene: 38233857

Following gene: 38233855

Centisome position: 51.35

GC content: 47.56

Gene sequence:

>1005_bases
GTGAAGAAAGCGCGGCGGCGTATAGATGTTGACGAATTATTTGAAGGCGTCCGTCGAGGTGATCGAACGCTTATTTCTCG
AGCTATCACCTTGCTAGAATCTACTGCTCCGGCACACAGGGTTTTGGCTCAAGAATTGCTGGTCAAGTTGTTGCCATTTA
GCGGTAAAGCGCTTCGAGTAGGTATCACTGGTGTACCCGGCGTGGGAAAATCAACGTTTATTGAGGCGTTGGGGATGAAG
CTGATTGGTGATGGACATAAACTAGCGGTGCTTGCCATCGATCCTTCCTCCACAAAGACACGAGGCTCAATCTTGGGCGA
TAAAACTCGTATGGCTAAGTTAGCTCGTGAAGATAATGCCTTTATTCGTCCTTCTCCTTCCGCTGGAACTCTCGGCGGCG
TTGCTAAAGCTACTCGTGAATCTATGGTGGTTTTCGAGGCTGCAGGATACGATGTGATCCTTGTTGAAACCGTTGGCGTA
GGACAATCAGAAGTTGCTGTCTCACAAATGGTTGATTGTTTCACCTTTTTGGCTCTGGCTGGTGCGGGTGATCAACTACA
AGGAATCAAAAAAGGCATCCTTGAAATGGCAGATCTGGTTGCTATCAACAAAGCTGATGGCCCCAACCTCAAAAATGCGA
AACGAGCGGCTCGTGAATTGGCAGCTGCAATGCGAATGGTTCGTCAAGAAAACGACCTGTGGCACCCGCCTACGATTACT
ATGTCAGCCGTAGAGCATGAAGGCGTAGACGAATTCTGGGAGCATGTTCAAAATCACAATAAGGCAATGTTGGAATCTGG
CGTATTCGAGCATAATCGCAGAGAACAACAAGTTCAGTGGATGTGGTCAATGGTCCACGAGACTTTACTTCAACGGCTAA
ACACAGATCCGAATGTTGTTGAAGTGAAAAAATTGGTGGAAGATCAGCTACGGCACGCACACATCACACCTACATTAGCT
GCTGAACGAATTCTCAAAGCTTTTGATCATGTCACTGCCGACTAG

Upstream 100 bases:

>100_bases
AATGTCTGCAGACAACGAGTACCTCGAGCATCATTTGGGTTCACTTTTAACTACCGCTGGGACCGATTTGGGGGAGGTGA
CTGCTGTTGCCCCTGAGATT

Downstream 100 bases:

>100_bases
AGAAAAATCCTAGATGAATACGCACATTCCATCGCTTCTTACTGCGAAGGCTCTTCAACAGTTATGCGATAACCGTTCAA
ATGTCGTGATCTTGGACGCA

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKKARRRIDVDELFEGVRRGDRTLISRAITLLESTAPAHRVLAQELLVKLLPFSGKALRVGITGVPGVGKSTFIEALGMK
LIGDGHKLAVLAIDPSSTKTRGSILGDKTRMAKLAREDNAFIRPSPSAGTLGGVAKATRESMVVFEAAGYDVILVETVGV
GQSEVAVSQMVDCFTFLALAGAGDQLQGIKKGILEMADLVAINKADGPNLKNAKRAARELAAAMRMVRQENDLWHPPTIT
MSAVEHEGVDEFWEHVQNHNKAMLESGVFEHNRREQQVQWMWSMVHETLLQRLNTDPNVVEVKKLVEDQLRHAHITPTLA
AERILKAFDHVTAD

Sequences:

>Translated_334_residues
MKKARRRIDVDELFEGVRRGDRTLISRAITLLESTAPAHRVLAQELLVKLLPFSGKALRVGITGVPGVGKSTFIEALGMK
LIGDGHKLAVLAIDPSSTKTRGSILGDKTRMAKLAREDNAFIRPSPSAGTLGGVAKATRESMVVFEAAGYDVILVETVGV
GQSEVAVSQMVDCFTFLALAGAGDQLQGIKKGILEMADLVAINKADGPNLKNAKRAARELAAAMRMVRQENDLWHPPTIT
MSAVEHEGVDEFWEHVQNHNKAMLESGVFEHNRREQQVQWMWSMVHETLLQRLNTDPNVVEVKKLVEDQLRHAHITPTLA
AERILKAFDHVTAD
>Mature_334_residues
MKKARRRIDVDELFEGVRRGDRTLISRAITLLESTAPAHRVLAQELLVKLLPFSGKALRVGITGVPGVGKSTFIEALGMK
LIGDGHKLAVLAIDPSSTKTRGSILGDKTRMAKLAREDNAFIRPSPSAGTLGGVAKATRESMVVFEAAGYDVILVETVGV
GQSEVAVSQMVDCFTFLALAGAGDQLQGIKKGILEMADLVAINKADGPNLKNAKRAARELAAAMRMVRQENDLWHPPTIT
MSAVEHEGVDEFWEHVQNHNKAMLESGVFEHNRREQQVQWMWSMVHETLLQRLNTDPNVVEVKKLVEDQLRHAHITPTLA
AERILKAFDHVTAD

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=329, Percent_Identity=48.0243161094225, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1789285, Length=277, Percent_Identity=50.5415162454874, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71994271, Length=331, Percent_Identity=40.1812688821752, Blast_Score=253, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI71994275, Length=272, Percent_Identity=42.6470588235294, Blast_Score=238, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36672; Mature: 36672

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKARRRIDVDELFEGVRRGDRTLISRAITLLESTAPAHRVLAQELLVKLLPFSGKALRV
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
GITGVPGVGKSTFIEALGMKLIGDGHKLAVLAIDPSSTKTRGSILGDKTRMAKLAREDNA
EECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCC
FIRPSPSAGTLGGVAKATRESMVVFEAAGYDVILVETVGVGQSEVAVSQMVDCFTFLALA
EECCCCCCCCHHHHHHHHHHHEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GAGDQLQGIKKGILEMADLVAINKADGPNLKNAKRAARELAAAMRMVRQENDLWHPPTIT
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
MSAVEHEGVDEFWEHVQNHNKAMLESGVFEHNRREQQVQWMWSMVHETLLQRLNTDPNVV
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVKKLVEDQLRHAHITPTLAAERILKAFDHVTAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKARRRIDVDELFEGVRRGDRTLISRAITLLESTAPAHRVLAQELLVKLLPFSGKALRV
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
GITGVPGVGKSTFIEALGMKLIGDGHKLAVLAIDPSSTKTRGSILGDKTRMAKLAREDNA
EECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCC
FIRPSPSAGTLGGVAKATRESMVVFEAAGYDVILVETVGVGQSEVAVSQMVDCFTFLALA
EECCCCCCCCHHHHHHHHHHHEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GAGDQLQGIKKGILEMADLVAINKADGPNLKNAKRAARELAAAMRMVRQENDLWHPPTIT
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
MSAVEHEGVDEFWEHVQNHNKAMLESGVFEHNRREQQVQWMWSMVHETLLQRLNTDPNVV
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVKKLVEDQLRHAHITPTLAAERILKAFDHVTAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]