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The map label for this gene is sseA [H]

Identifier: 38233855

GI number: 38233855

Start: 1276058

End: 1276807

Strand: Reverse

Name: sseA [H]

Synonym: DIP1270

Alternate gene names: 38233855

Gene position: 1276807-1276058 (Counterclockwise)

Preceding gene: 38233856

Following gene: 38233853

Centisome position: 51.31

GC content: 48.53

Gene sequence:

>750_bases
TTGGGGATCTCTGAGCTCAAAATTCCGACAGCGCAGCGCTTTGACTTGGATGCTGAAATGTCTGATAGTTCCTCGGATAT
TCCACACACGCTTCCCACTAGGAAGGAATTTGAGAAGCAGCTTCGGACCCTCGGTATCGATAATTATTCGCTTGTCGTTG
TATACGGCAAGCGAGGAATGGACTCTACGCCTCGTGCTTGGTGGATGCTGAAATCCGCTGGCGTACAGAACGTGAGCTTG
GCCAATGGTGAGCTTGCTGCATGGATTGCGGCTGGAAATAGAACTGAGTTTTGGGAAGACAAAGCAGCTTCTCAAAATAA
GCGAAATATTACCGTAAGTAGTTCTTTTGGGTCGAACAGCGTCAATATGCAGTGGTTGAGAGCAAGAGGGAGCCAACTTG
AAATACCAATTGTTGATGCACGTAGCATTGAGCGGTATCACGGTGAGGTGGAAGAGCCTCACAAAGGTCTAAACCGAGGC
CATATCCCTGGAGCAATCAACATACCGTTTACGACTTTGCAAGCAAATGGTCAATTAGTGTCGCTCGATCAACTCCGTAG
CATTTTTGATCAGCATCTAGGTTGTGCGAATAGGCCATTCATTGCTTACTGTGGCTCCAGAGTCACAGCCTGTGTCGTCC
TTTTCGCTGCGTCCCTTATCGGACAACACGGACTGCTTTACGATGGTTCTTGGTCGAAGTGGGGGAGACAAGACTACGAC
AATCCGGTTGCTACCAAGGATGAGGTTTGA

Upstream 100 bases:

>100_bases
ATGAATACGCACATTCCATCGCTTCTTACTGCGAAGGCTCTTCAACAGTTATGCGATAACCGTTCAAATGTCGTGATCTT
GGACGCAAGCTTGACCATAT

Downstream 100 bases:

>100_bases
AGTCTTTCAGAAAGCATCCATATAGATCTACCCAATTTTCGCCTTGGACAATAGGGTCGTTGACTCGTGACGCACCGTCA
ACTAAGCCGAGAGGCGCGCG

Product: putative sulfurtransferase

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MGISELKIPTAQRFDLDAEMSDSSSDIPHTLPTRKEFEKQLRTLGIDNYSLVVVYGKRGMDSTPRAWWMLKSAGVQNVSL
ANGELAAWIAAGNRTEFWEDKAASQNKRNITVSSSFGSNSVNMQWLRARGSQLEIPIVDARSIERYHGEVEEPHKGLNRG
HIPGAINIPFTTLQANGQLVSLDQLRSIFDQHLGCANRPFIAYCGSRVTACVVLFAASLIGQHGLLYDGSWSKWGRQDYD
NPVATKDEV

Sequences:

>Translated_249_residues
MGISELKIPTAQRFDLDAEMSDSSSDIPHTLPTRKEFEKQLRTLGIDNYSLVVVYGKRGMDSTPRAWWMLKSAGVQNVSL
ANGELAAWIAAGNRTEFWEDKAASQNKRNITVSSSFGSNSVNMQWLRARGSQLEIPIVDARSIERYHGEVEEPHKGLNRG
HIPGAINIPFTTLQANGQLVSLDQLRSIFDQHLGCANRPFIAYCGSRVTACVVLFAASLIGQHGLLYDGSWSKWGRQDYD
NPVATKDEV
>Mature_248_residues
GISELKIPTAQRFDLDAEMSDSSSDIPHTLPTRKEFEKQLRTLGIDNYSLVVVYGKRGMDSTPRAWWMLKSAGVQNVSLA
NGELAAWIAAGNRTEFWEDKAASQNKRNITVSSSFGSNSVNMQWLRARGSQLEIPIVDARSIERYHGEVEEPHKGLNRGH
IPGAINIPFTTLQANGQLVSLDQLRSIFDQHLGCANRPFIAYCGSRVTACVVLFAASLIGQHGLLYDGSWSKWGRQDYDN
PVATKDEV

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=236, Percent_Identity=33.8983050847458, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI61835204, Length=236, Percent_Identity=33.8983050847458, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI194473681, Length=236, Percent_Identity=33.8983050847458, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI17402865, Length=238, Percent_Identity=33.6134453781513, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI87082121, Length=238, Percent_Identity=38.655462184874, Blast_Score=155, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71997283, Length=237, Percent_Identity=29.957805907173, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17561888, Length=241, Percent_Identity=29.8755186721992, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534702, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324825, Length=254, Percent_Identity=27.5590551181102, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 27638; Mature: 27507

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISELKIPTAQRFDLDAEMSDSSSDIPHTLPTRKEFEKQLRTLGIDNYSLVVVYGKRGM
CCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
DSTPRAWWMLKSAGVQNVSLANGELAAWIAAGNRTEFWEDKAASQNKRNITVSSSFGSNS
CCCCHHEEEEHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCCC
VNMQWLRARGSQLEIPIVDARSIERYHGEVEEPHKGLNRGHIPGAINIPFTTLQANGQLV
CCHHEEECCCCEEEEEEECHHHHHHHCCCCCCHHHCCCCCCCCCEEECCEEEEECCCCEE
SLDQLRSIFDQHLGCANRPFIAYCGSRVTACVVLFAASLIGQHGLLYDGSWSKWGRQDYD
CHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCC
NPVATKDEV
CCCCCCCCC
>Mature Secondary Structure 
GISELKIPTAQRFDLDAEMSDSSSDIPHTLPTRKEFEKQLRTLGIDNYSLVVVYGKRGM
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
DSTPRAWWMLKSAGVQNVSLANGELAAWIAAGNRTEFWEDKAASQNKRNITVSSSFGSNS
CCCCHHEEEEHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCCC
VNMQWLRARGSQLEIPIVDARSIERYHGEVEEPHKGLNRGHIPGAINIPFTTLQANGQLV
CCHHEEECCCCEEEEEEECHHHHHHHCCCCCCHHHCCCCCCCCCEEECCEEEEECCCCEE
SLDQLRSIFDQHLGCANRPFIAYCGSRVTACVVLFAASLIGQHGLLYDGSWSKWGRQDYD
CHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCC
NPVATKDEV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]