Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 38233850

GI number: 38233850

Start: 1268849

End: 1269697

Strand: Reverse

Name: uppP

Synonym: DIP1262

Alternate gene names: 38233850

Gene position: 1269697-1268849 (Counterclockwise)

Preceding gene: 38233853

Following gene: 38233849

Centisome position: 51.02

GC content: 47.59

Gene sequence:

>849_bases
TTGACTCAAGATCCGTCGAGTCAAATAAGCTGGTCCCAGACAATTGTGCTCTCTATCGTTCAAGGCCTCACCGAGTTTCT
TCCTATTAGTTCATCCGGCCATCTGCGAATTGTCTCTGAGCTTTTTTGGGGCAAAGACGCTGGTGCAAGTTTTACTGCTG
TCGTTCAACTAGGCACTGAAGCAGCAGTTCTCGTTTACTTCGCTAAAGATATTGCAAAGATTCTCACTGGCTGGTTTAGA
GGCCTTTTTGATAAAAAGCAACGAGGTTTCGATTACCGTATGGGATGGATGGTCATCGTTGGCACATTGCCGGTAAGTAT
CGTAGGGCTGCTAGCTAAAGACATCATCCGAGACAATCTACGAAATATGTGGATTACCGCATCAGTGTTAATCGCTTTTT
CTTTTGTATTTATCGCTGCCGAAAAATGGGGTAGTAAGCGTCGCAGCTTTGACCAACTGACAATGAGAGACGCCGTAATT
ATGGGCTGTGCACAGTGTTTGGCATTAATACCAGGTGTTTCACGGTCAGGTGGCACCGTTTCTGCAGGTTTATTCGTCGG
ACTTGATAGGGAAGTTGCAACTCGCTTTAGTTTCCTATTGGCTATCCCCGCAGTGTTAGCATCTGGCTTATTCTCGCTTC
CCGACGCCTTTGCTCCCGACGCGGGGCAGGCGGCCTCGGGTATGCAACTTGCTGTAGGTACCGGAATTGCTTTTGCCCTA
GGGTATGCTTCCATCGCGTGGCTTTTGAAATTCGTTGGTAGTCACTCGTTTAGCTGGTTTGCAGCTTATCGAATCCCTGT
CGGTTTGCTTGTTATGGCATTACTAGCTACCGGAATGCTAACCGCTTAA

Upstream 100 bases:

>100_bases
GATTAGGCATATCCATGTAGTTCTGCATCACTGACATATGTTGGACTTTGAACAGGTATTCTTGTGCCCCGTGACTGATG
TAAATGTATTAGCCCAAGCA

Downstream 100 bases:

>100_bases
CTACTGTAATGTGTCATTGCTGCCTCAGCAGGTAATGTTGATGGCATGCAATCTTGGCCCATGCCGACAATTCCTTCAGT
GCCGGGTAAACCGGCTGTAC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTQDPSSQISWSQTIVLSIVQGLTEFLPISSSGHLRIVSELFWGKDAGASFTAVVQLGTEAAVLVYFAKDIAKILTGWFR
GLFDKKQRGFDYRMGWMVIVGTLPVSIVGLLAKDIIRDNLRNMWITASVLIAFSFVFIAAEKWGSKRRSFDQLTMRDAVI
MGCAQCLALIPGVSRSGGTVSAGLFVGLDREVATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAASGMQLAVGTGIAFAL
GYASIAWLLKFVGSHSFSWFAAYRIPVGLLVMALLATGMLTA

Sequences:

>Translated_282_residues
MTQDPSSQISWSQTIVLSIVQGLTEFLPISSSGHLRIVSELFWGKDAGASFTAVVQLGTEAAVLVYFAKDIAKILTGWFR
GLFDKKQRGFDYRMGWMVIVGTLPVSIVGLLAKDIIRDNLRNMWITASVLIAFSFVFIAAEKWGSKRRSFDQLTMRDAVI
MGCAQCLALIPGVSRSGGTVSAGLFVGLDREVATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAASGMQLAVGTGIAFAL
GYASIAWLLKFVGSHSFSWFAAYRIPVGLLVMALLATGMLTA
>Mature_281_residues
TQDPSSQISWSQTIVLSIVQGLTEFLPISSSGHLRIVSELFWGKDAGASFTAVVQLGTEAAVLVYFAKDIAKILTGWFRG
LFDKKQRGFDYRMGWMVIVGTLPVSIVGLLAKDIIRDNLRNMWITASVLIAFSFVFIAAEKWGSKRRSFDQLTMRDAVIM
GCAQCLALIPGVSRSGGTVSAGLFVGLDREVATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAASGMQLAVGTGIAFALG
YASIAWLLKFVGSHSFSWFAAYRIPVGLLVMALLATGMLTA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=255, Percent_Identity=34.9019607843137, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CORDI (P60937)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939617.1
- GeneID:   2649816
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1262
- NMPDR:   fig|257309.1.peg.1208
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- PhylomeDB:   P60937
- ProtClustDB:   PRK00281
- BioCyc:   CDIP257309:DIP1262-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30248; Mature: 30117

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117ffda0)-; HASH(0x11f85d34)-; HASH(0x125bac78)-; HASH(0x11f71730)-; HASH(0x11f78c84)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDPSSQISWSQTIVLSIVQGLTEFLPISSSGHLRIVSELFWGKDAGASFTAVVQLGTE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEHEECCCC
AAVLVYFAKDIAKILTGWFRGLFDKKQRGFDYRMGWMVIVGTLPVSIVGLLAKDIIRDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHH
RNMWITASVLIAFSFVFIAAEKWGSKRRSFDQLTMRDAVIMGCAQCLALIPGVSRSGGTV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
SAGLFVGLDREVATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAASGMQLAVGTGIAFAL
EEHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHH
GYASIAWLLKFVGSHSFSWFAAYRIPVGLLVMALLATGMLTA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
TQDPSSQISWSQTIVLSIVQGLTEFLPISSSGHLRIVSELFWGKDAGASFTAVVQLGTE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEHEECCCC
AAVLVYFAKDIAKILTGWFRGLFDKKQRGFDYRMGWMVIVGTLPVSIVGLLAKDIIRDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHH
RNMWITASVLIAFSFVFIAAEKWGSKRRSFDQLTMRDAVIMGCAQCLALIPGVSRSGGTV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
SAGLFVGLDREVATRFSFLLAIPAVLASGLFSLPDAFAPDAGQAASGMQLAVGTGIAFAL
EEHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHH
GYASIAWLLKFVGSHSFSWFAAYRIPVGLLVMALLATGMLTA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14602910