Click here to switch to the map view.

The map label for this gene is ptsG [H]

Identifier: 38233741

GI number: 38233741

Start: 1137670

End: 1139700

Strand: Reverse

Name: ptsG [H]

Synonym: DIP1151

Alternate gene names: 38233741

Gene position: 1139700-1137670 (Counterclockwise)

Preceding gene: 38233746

Following gene: 38233740

Centisome position: 45.8

GC content: 54.31

Gene sequence:

>2031_bases
ATGTCTACGCAAACACGCGAAGATACCGCTCGGGCCATCCTTGATGGCATCGGTGGCGCGAGCAACATTACGTCGTTTAC
GCACTGTGCAACTCGCCTGCGTTTCGAGCTTGCCGACGCCTCCAAGGTTGATAAAGCAGCCCTCGACTCCATACCTAAGG
TCATGGGTGCGGTCCCACAAGGTGGCCGTAATTATCAGGTCGTTATTGGTGGCGACGTAGCCAACGTCTATGACGACATG
ACCCACCTTCCCGAGATGAAGTCTGCGGCTCCTTCAGATGCTGATATCAAGGCTGCGGCTCGCGCAAAGTCTAAGGGCAA
ACTGCCATGGATGGACTCCTTCTTTGAGTACCTATCCGACTCCTTCCGCCCAATTTTGGGCGTGCTGCTGGGCGCCTCCC
TCATTATCGCGTTCACGGCTGTGCTCGACGCATTCCACATCGTCGACTTCCGCGCAGACGACAAGTCGGCTTCTTGGGTC
TTCGTCGATGCAATGTGGCGCTCAGTCTTCTACTTCCTGCCAGTCATGGTGGCCTTCAACGCGGGTAAGAAACTGCGTAT
CGATCCGTGGGTTCCAGCCGCCATTATGTTTGCGCTATTTACCCCAGAGTTCCTTGGTCTTAAAGAGAGCTCTACTGCGG
AATGCGTGACCAACGCAGCCCTGGGCACTGAAACCTGCCACGCTCCAATCTTCGGCATCAACATGACTTTCCCCGATTAC
GGCGGAAACGTCTTCGTGCCATTGATCATGGCCGCTGTCGCTGCCGTTGTTTACAAGGGCTTCCAGAAAGTTATCCCTAC
CGCAGTTCACATGGTTTTCGTACCATTCCTGACTTTGGTCATTATGATTCCTGTGACCGCCTTCATCATCGGCCCATTCG
GCACCTGGGCTGGTAACGGTATCGGTCTTGGCTTGTCCTGGATGAACGAGAACGCACCATTCGTCTTCGCTCTTGCTATT
CCACTGCTATACCCATTCTTGGTTCCACTCGGTCTGCACTGGCCTCTGAACGCCTTGATGCTTATCAACATTCAGACCTT
GGGCTACGACTTCATTCAAGGCCCTATGGGTACTTGGAACTTCGCTTGCTTCGGTGCTACCGCCGGCGTCTTGGCACTGT
CCATCCGCGACAAGGACACCGTAATGCGACAGACCGCTGGTTCTGCTCTAGCTGCAGGTCTTCTCGGCGGCATCTCCGAG
CCTTCCCTCTACGGTATTCACCTCCGCTTCAAACGCGTGTACCCACGTATGCTCGCCGGATGTTTTGCAGGCGGCTTGAC
CATCGCTGTATTGTCCACCATCTTCGAACCAGTAACCACTAACGCCTTCGTCTTTACTTCGATCCCAACTATGTTCGTGT
TTAACCCAGCATGGATCTACATGGTTTCGATCTTGGTCGCCTTCACCGTGGCATTCCTCGCCATCTTCATCACCGACTAC
CGCACTACAGAAGAAAAAGCAGAATTCTTTGCTCGTCGCGACAGTGCTGACGATGTTCCTGCCGCAACAGTCCCATCAGC
TACTACCCCAGCGCCTGCAGCTGCAGCTGCTAATCCTGCTGGCGAGTGCAAAGTCGGCTCCCCTATTTCCGGCGAAGTAC
TCCCTATGGCAGAAATCGCCGATCCTGTATTTTCCGCAGGCACACTAGGCGACGGCGTCGGAGTTAACCCAACGGCGACT
GCTGGTGCCGGCACAGAGGTTTATTCACCAGTCTCCGGCACCGTTAAATCTGCCATGAAGTCCGGCCATGCTTACGGAAT
TAAGACAGATGACGGCGTCGAGGTTCTCGTTCACATCGGAATTGATACCGTTCAAATGAAGGGCGAAGGTTTCACTCCTG
CAGTCCAAAAGGGCGACCGTGTTGAAGCAGGACAAAAACTCGCAACTGTTGATTATGACAAGGTTCGCGCTGCAGGATAT
GGCACCACCATCGTCGTTGCAGTTACCAACACAAAGGCAATGAAGGCCGTAACCCCAACCGGCGTCAAGCATGCCGGCGC
GGGTGACACCATCTTCACTGTTACGCAATAA

Upstream 100 bases:

>100_bases
CGGGCAAGACCTAGGACGCTTAATTGCAGCGCCCTAGGTCTTTTGTGGTTTCTAAGCTTTTAAAGAGATCGAGCCCATCC
ATAAATGAAAGGAAAAGCGA

Downstream 100 bases:

>100_bases
ACTGAACATTCGATACGGCCCCCTGTTATAGGGCAGCCTTCGAAGTCACTGCGAGCCAAGAGCAGGGTCGTTTCCTTTCA
AGGAAGCGGCCCTGCTTTAG

Product: PTS system, glucose-specific IIABC component

Products: NA

Alternate protein names: EII-Man/EIII-Man; EIIBCA-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDM
THLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWV
FVDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY
GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAI
PLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISE
PSLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY
RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTAT
AGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGY
GTTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ

Sequences:

>Translated_676_residues
MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDM
THLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWV
FVDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY
GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAI
PLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISE
PSLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY
RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTAT
AGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGY
GTTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ
>Mature_675_residues
STQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQGGRNYQVVIGGDVANVYDDMT
HLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSDSFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVF
VDAMWRSVFYFLPVMVAFNAGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDYG
GNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNGIGLGLSWMNENAPFVFALAIP
LLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWNFACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEP
SLYGIHLRFKRVYPRMLAGCFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDYR
TTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIADPVFSAGTLGDGVGVNPTATA
GAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIGIDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYG
TTIVVAVTNTKAMKAVTPTGVKHAGAGDTIFTVTQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=683, Percent_Identity=30.1610541727672, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI48994906, Length=494, Percent_Identity=25.5060728744939, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI2367362, Length=468, Percent_Identity=25.8547008547009, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788757, Length=135, Percent_Identity=34.0740740740741, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786894, Length=156, Percent_Identity=32.6923076923077, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788769, Length=486, Percent_Identity=24.6913580246914, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 71600; Mature: 71468

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQ
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCC
GGRNYQVVIGGDVANVYDDMTHLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSD
CCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
SFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVFVDAMWRSVFYFLPVMVAFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHC
AGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY
CCCEEEECCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC
GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IGLGLSWMNENAPFVFALAIPLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWN
EEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCHHHHCCCCCCCC
FACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEPSLYGIHLRFKRVYPRMLAG
EEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH
CFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC
RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEHHHHH
DPVFSAGTLGDGVGVNPTATAGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIG
CHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEC
IDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYGTTIVVAVTNTKAMKAVTPT
CEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCEEEECCC
GVKHAGAGDTIFTVTQ
CCCCCCCCCEEEEECC
>Mature Secondary Structure 
STQTREDTARAILDGIGGASNITSFTHCATRLRFELADASKVDKAALDSIPKVMGAVPQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCC
GGRNYQVVIGGDVANVYDDMTHLPEMKSAAPSDADIKAAARAKSKGKLPWMDSFFEYLSD
CCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
SFRPILGVLLGASLIIAFTAVLDAFHIVDFRADDKSASWVFVDAMWRSVFYFLPVMVAFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHC
AGKKLRIDPWVPAAIMFALFTPEFLGLKESSTAECVTNAALGTETCHAPIFGINMTFPDY
CCCEEEECCCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC
GGNVFVPLIMAAVAAVVYKGFQKVIPTAVHMVFVPFLTLVIMIPVTAFIIGPFGTWAGNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IGLGLSWMNENAPFVFALAIPLLYPFLVPLGLHWPLNALMLINIQTLGYDFIQGPMGTWN
EEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCHHHHCCCCCCCC
FACFGATAGVLALSIRDKDTVMRQTAGSALAAGLLGGISEPSLYGIHLRFKRVYPRMLAG
EEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH
CFAGGLTIAVLSTIFEPVTTNAFVFTSIPTMFVFNPAWIYMVSILVAFTVAFLAIFITDY
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC
RTTEEKAEFFARRDSADDVPAATVPSATTPAPAAAAANPAGECKVGSPISGEVLPMAEIA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEHHHHH
DPVFSAGTLGDGVGVNPTATAGAGTEVYSPVSGTVKSAMKSGHAYGIKTDDGVEVLVHIG
CHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEC
IDTVQMKGEGFTPAVQKGDRVEAGQKLATVDYDKVRAAGYGTTIVVAVTNTKAMKAVTPT
CEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCEEEECCC
GVKHAGAGDTIFTVTQ
CCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8039653; 12948626 [H]