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The map label for this gene is allR [H]

Identifier: 38233716

GI number: 38233716

Start: 1111173

End: 1111898

Strand: Reverse

Name: allR [H]

Synonym: DIP1126

Alternate gene names: 38233716

Gene position: 1111898-1111173 (Counterclockwise)

Preceding gene: 38233719

Following gene: 38233714

Centisome position: 44.68

GC content: 57.85

Gene sequence:

>726_bases
ATGGGAAAGATTAACACAGATCCTGCTGCAACAAGCGGCATTAAGGTTCTCGACCGCGCTGTCTCCATCATGCTCGCAGT
CGCGGAACGTCCACTATCGCTCACCGAACTGTGCGACGTGACCAATCTCCCCCGAGCCACAGCACACAGACTGGCCACAG
CGCTAGAAACCCATAACATCCTGACACGTACCTCCGATGGCAAATGGACCATCGGCGCAGTCTTGAGCTCGCTCGGGGCC
GGTAGCTCCACCAAGCTTATCGACGTAGCCACCCCGATCATGACTAGCCTCATGAACGAAACTGGCGAATCCGTGCAGCT
GTACCAACTCGCAGGCGCAACCCGTGTATGTATTGCAGCCCAAGAGCCCACCATTGGACTACAAAACACCGTCCCCGTGG
GCACACGACTACCACTGACCGCTGGATCCGCAGCAAAGGTCTTTCTTGCCTACTCCTCCCCTACATTGCGCGATGCCATG
CTGGCATCGGGGGCGCAGTTTACCCCCGAAGACCTTGAAGAGGCCCGCGACCGCGGCTGGTCGGAATCGATTAGCGAACG
CGAAGTTGGCCTCGCAAGTATTTCTGCCCCCGTCTTCGACAGCGAAGGTCTTTTCATCGCCGTACTGTCTATCTCCGGCC
CCACCGAGCGCCTGCGCCCATCACCTTCCACACTATGGTCACAGCAACTAACCGAAGCTGCGGCACATCTATCGCAATCA
CTCTAG

Upstream 100 bases:

>100_bases
GGGCTGGTCATGAATCGAATCACCTCTTCTACATAAATTTTCCACTACATCAAACGACCCACAGGTGAATCCCGCGCAAT
GGAATGCTAATATTCATCTT

Downstream 100 bases:

>100_bases
GCATTACTCATTACGCCTTAGCAAACATGCTCAGCAGGCGGGCATAGTCCGCCACCCCTGGAAAATCTTTGCCAAGCCTG
CGCTCCAGCACATCCCACAC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGKINTDPAATSGIKVLDRAVSIMLAVAERPLSLTELCDVTNLPRATAHRLATALETHNILTRTSDGKWTIGAVLSSLGA
GSSTKLIDVATPIMTSLMNETGESVQLYQLAGATRVCIAAQEPTIGLQNTVPVGTRLPLTAGSAAKVFLAYSSPTLRDAM
LASGAQFTPEDLEEARDRGWSESISEREVGLASISAPVFDSEGLFIAVLSISGPTERLRPSPSTLWSQQLTEAAAHLSQS
L

Sequences:

>Translated_241_residues
MGKINTDPAATSGIKVLDRAVSIMLAVAERPLSLTELCDVTNLPRATAHRLATALETHNILTRTSDGKWTIGAVLSSLGA
GSSTKLIDVATPIMTSLMNETGESVQLYQLAGATRVCIAAQEPTIGLQNTVPVGTRLPLTAGSAAKVFLAYSSPTLRDAM
LASGAQFTPEDLEEARDRGWSESISEREVGLASISAPVFDSEGLFIAVLSISGPTERLRPSPSTLWSQQLTEAAAHLSQS
L
>Mature_240_residues
GKINTDPAATSGIKVLDRAVSIMLAVAERPLSLTELCDVTNLPRATAHRLATALETHNILTRTSDGKWTIGAVLSSLGAG
SSTKLIDVATPIMTSLMNETGESVQLYQLAGATRVCIAAQEPTIGLQNTVPVGTRLPLTAGSAAKVFLAYSSPTLRDAML
ASGAQFTPEDLEEARDRGWSESISEREVGLASISAPVFDSEGLFIAVLSISGPTERLRPSPSTLWSQQLTEAAAHLSQSL

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=230, Percent_Identity=31.7391304347826, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082359, Length=245, Percent_Identity=29.7959183673469, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788131, Length=228, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789999, Length=267, Percent_Identity=25.0936329588015, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 25344; Mature: 25213

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKINTDPAATSGIKVLDRAVSIMLAVAERPLSLTELCDVTNLPRATAHRLATALETHNI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTRTSDGKWTIGAVLSSLGAGSSTKLIDVATPIMTSLMNETGESVQLYQLAGATRVCIAA
EEECCCCCEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEE
QEPTIGLQNTVPVGTRLPLTAGSAAKVFLAYSSPTLRDAMLASGAQFTPEDLEEARDRGW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCC
SESISEREVGLASISAPVFDSEGLFIAVLSISGPTERLRPSPSTLWSQQLTEAAAHLSQS
HHHHHHHHCCHHHCCCCCCCCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
GKINTDPAATSGIKVLDRAVSIMLAVAERPLSLTELCDVTNLPRATAHRLATALETHNI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTRTSDGKWTIGAVLSSLGAGSSTKLIDVATPIMTSLMNETGESVQLYQLAGATRVCIAA
EEECCCCCEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEE
QEPTIGLQNTVPVGTRLPLTAGSAAKVFLAYSSPTLRDAMLASGAQFTPEDLEEARDRGW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCC
SESISEREVGLASISAPVFDSEGLFIAVLSISGPTERLRPSPSTLWSQQLTEAAAHLSQS
HHHHHHHHCCHHHCCCCCCCCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA