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The map label for this gene is nudL [H]

Identifier: 37680267

GI number: 37680267

Start: 2089144

End: 2089770

Strand: Direct

Name: nudL [H]

Synonym: VV2083

Alternate gene names: 37680267

Gene position: 2089144-2089770 (Clockwise)

Preceding gene: 37680264

Following gene: 37680268

Centisome position: 62.28

GC content: 45.61

Gene sequence:

>627_bases
ATGACGGGCAGAGGTAATACCTTGTTTGAGCTTAATAAAAATCAACTATTACAATCTTTTCAGTTCAATCTGCCTCGCGG
TTATCACGCAGAGTCCACCGCACGTGTTGCACACTTGAAAGGCAGTAAGCTTCGCGATGCCGCCGTGTTAATTGGCTTTG
TTGAACGAGAACAAGGCTTGAATGTGATTCTGACTAAACGCGCCTCTCATCTGAAACATCATCCGGGACAAATCAGCTTT
CCGGGTGGCAAGTACGAAGAGAGTGATCGTTCTTTACAAGCAACGGCGTTGCGCGAGACCCGCGAAGAGATAGGAATTGC
ACCAGATGCGATCTCCATTTTTGGCCAAATGCCGGAATTGGTTACCGTCAGTCGGTTCAAAGTCACACCAATATTGGCGT
TTGTCGAACCAAATTATCAAATCGTCATTGATAAAAATGAGGTCGATGAGGTGTTCGAAGTTCCCGCCAATCACCTACTT
GATACGCAGAAACTGAAAAGTGCCCAGTTTCGCGTGAATCAATCTCATCATCGAGTCTTTGCCATTCCCTATCAGCATCA
TTTTATCTGGGGGATGACTGCCCAGATAATCCAAGCCATGCAGCAACAAATTATGAAACGAGGTTAA

Upstream 100 bases:

>100_bases
TTCCAAAAATTCAGTGAAAATGATTCCCTTCATTTTTTGCGCTACCCTGTAATTAGACGCTATGCCAAATAAGCATGGTG
TATAAAGTAGGTTTGATCAA

Downstream 100 bases:

>100_bases
GAGTTGTTAACGGCCTCGTTACCAAGCATCGGGTTAGTTATTTTAATCTCCGCCAAAGCAAACGGTTGGCATGAGAATAT
TTTGTACAAACACCCCTTCA

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTGRGNTLFELNKNQLLQSFQFNLPRGYHAESTARVAHLKGSKLRDAAVLIGFVEREQGLNVILTKRASHLKHHPGQISF
PGGKYEESDRSLQATALRETREEIGIAPDAISIFGQMPELVTVSRFKVTPILAFVEPNYQIVIDKNEVDEVFEVPANHLL
DTQKLKSAQFRVNQSHHRVFAIPYQHHFIWGMTAQIIQAMQQQIMKRG

Sequences:

>Translated_208_residues
MTGRGNTLFELNKNQLLQSFQFNLPRGYHAESTARVAHLKGSKLRDAAVLIGFVEREQGLNVILTKRASHLKHHPGQISF
PGGKYEESDRSLQATALRETREEIGIAPDAISIFGQMPELVTVSRFKVTPILAFVEPNYQIVIDKNEVDEVFEVPANHLL
DTQKLKSAQFRVNQSHHRVFAIPYQHHFIWGMTAQIIQAMQQQIMKRG
>Mature_207_residues
TGRGNTLFELNKNQLLQSFQFNLPRGYHAESTARVAHLKGSKLRDAAVLIGFVEREQGLNVILTKRASHLKHHPGQISFP
GGKYEESDRSLQATALRETREEIGIAPDAISIFGQMPELVTVSRFKVTPILAFVEPNYQIVIDKNEVDEVFEVPANHLLD
TQKLKSAQFRVNQSHHRVFAIPYQHHFIWGMTAQIIQAMQQQIMKRG

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=151, Percent_Identity=31.1258278145695, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788115, Length=160, Percent_Identity=38.125, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536993, Length=126, Percent_Identity=34.1269841269841, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859683, Length=156, Percent_Identity=34.6153846153846, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23638; Mature: 23507

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRGNTLFELNKNQLLQSFQFNLPRGYHAESTARVAHLKGSKLRDAAVLIGFVEREQGL
CCCCCCEEEEECHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCHHHEEEEHHHCCCC
NVILTKRASHLKHHPGQISFPGGKYEESDRSLQATALRETREEIGIAPDAISIFGQMPEL
EEEEECCHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
VTVSRFKVTPILAFVEPNYQIVIDKNEVDEVFEVPANHLLDTQKLKSAQFRVNQSHHRVF
EEHHEEEEEEEEEEECCCEEEEEECCCHHHHHHCCHHHHHCHHHHHHHHHEECCCCCEEE
AIPYQHHFIWGMTAQIIQAMQQQIMKRG
EEECCCEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGRGNTLFELNKNQLLQSFQFNLPRGYHAESTARVAHLKGSKLRDAAVLIGFVEREQGL
CCCCCEEEEECHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCHHHEEEEHHHCCCC
NVILTKRASHLKHHPGQISFPGGKYEESDRSLQATALRETREEIGIAPDAISIFGQMPEL
EEEEECCHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
VTVSRFKVTPILAFVEPNYQIVIDKNEVDEVFEVPANHLLDTQKLKSAQFRVNQSHHRVF
EEHHEEEEEEEEEEECCCEEEEEECCCHHHHHHCCHHHHHCHHHHHHHHHEECCCCCEEE
AIPYQHHFIWGMTAQIIQAMQQQIMKRG
EEECCCEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA