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The map label for this gene is bioI [H]

Identifier: 37521504

GI number: 37521504

Start: 2058447

End: 2059673

Strand: Reverse

Name: bioI [H]

Synonym: gll1935

Alternate gene names: 37521504

Gene position: 2059673-2058447 (Counterclockwise)

Preceding gene: 37521505

Following gene: 37521503

Centisome position: 44.21

GC content: 63.57

Gene sequence:

>1227_bases
ATGAGTGCCCTGCCACCGCCCCGGTTCAATCCTTTCGATTCTGAGTTTCGCCAAGACCCCTACCGCGTCTACGCGCATCT
GCGGGTGGCCGCTCCTATCCACCGCAGCCTGGGGATGTGGGTGCTGACGCGTTATGCCGATGTCCTGGCGGTGCTCAAAG
ATCCGCACTTCAGTTCCAGCCAGATTCCGCTGGCGGTCCGGCAGCGCAGCGAGAGACCAGACCAGGCCCAGAGTCATCCC
CTGGCTCGGCTTGCCGCCAAATCGATCGTCTTTACCGACGAACCCGACCACACCCGCCTGCGCCATCTGGTCGTCAGGGC
GATCAAGCGCCGAACGCCCGAGCAGGAGCAGGCCCATCTCACCCGCATCGCCTCCGCGCTGCTGGAGCGCGTCGGTCCCA
AAGGCCGCATGGATGCGGTCGCCGATTACGCGGAGCGCTTGCCGCTGCAGTTTATGGCCGAGTCGATGGCGTTGCCGCCG
GACAGCTGGCAGACCGTCCGCGACTGGACCCACCAGTTGCGCTATCTGCTGGAGCCGGGGCTGATGGGCAGGGGAGACTT
TGAGCGGGTTCAGGCGGTGCTGGATGAGGTGATCGCTTTTTTTGAGGACATGCTGGCTGTGCGGCGTCAGCAGCCCGGCG
ACGATCTGATCAGCGCCCTGGATGCCGCTCACCGTGAAGCGCAGGCGGATCGGCTGAGCGACGAAGAAATCGTCTACTGC
TGCATCATGATGTTCGTGGCAGGCCACGAAACCACCCGCAGTTTGATCGCAAGCGGCTTACTCGCCCTGCTGCAGCATCC
CGAGCAACTGGCCTATCTACGAATGCACCCCGAGCGGATGGGTGCCGCCGTCACCGAAATGCTGCGCTACGAAAGCCCTC
TGCAGCAGACCAAGCGCCGGGCGACCGCCGCTGTCGCCGTCGGCGGCCGGACCATTCAGCCGCAGGAGCAGGTTCTGTTG
TGCCTGGGGGCGGCCAATCGCGATCCTGCCCGCTTCGAGCAACCGGACCGCTTCGATATCACCCGCACCGACAATGGACA
TCTTGCTTTCGGGCAAGGCATGCACCACTGTCTGGGTGCCGCTCTAGCTCAAATGGAAGCGCAGGTGGCTTTGCGCGTGT
TGCTGGAGCGTTTTGCCAACCTGACGTTACAGGATACCCCCGAGTGGTTGGAGCACAGCTTCATCCTGCGGGGACTGAAG
ACACTTCCCGTGCAATGGGACCGATGA

Upstream 100 bases:

>100_bases
AACGCTATTTAAAAATGTCGTCGGTCGGCTTTCGCATGGGCAAAATCGGCCTGTTGCGCCTGGTGCTCGAACCGATCCGT
TCGCGCTGGCACCGTGCGTC

Downstream 100 bases:

>100_bases
ATTTACCGAACAATCATCTCGGCAGTGCACCGTATTTTGCGGCGGCGGAGTGGTTCCGCTGGTGTACACCCAACCCGGGC
GCACGGCTGCGTTTATTCTG

Product: cytochrome P450 like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSALPPPRFNPFDSEFRQDPYRVYAHLRVAAPIHRSLGMWVLTRYADVLAVLKDPHFSSSQIPLAVRQRSERPDQAQSHP
LARLAAKSIVFTDEPDHTRLRHLVVRAIKRRTPEQEQAHLTRIASALLERVGPKGRMDAVADYAERLPLQFMAESMALPP
DSWQTVRDWTHQLRYLLEPGLMGRGDFERVQAVLDEVIAFFEDMLAVRRQQPGDDLISALDAAHREAQADRLSDEEIVYC
CIMMFVAGHETTRSLIASGLLALLQHPEQLAYLRMHPERMGAAVTEMLRYESPLQQTKRRATAAVAVGGRTIQPQEQVLL
CLGAANRDPARFEQPDRFDITRTDNGHLAFGQGMHHCLGAALAQMEAQVALRVLLERFANLTLQDTPEWLEHSFILRGLK
TLPVQWDR

Sequences:

>Translated_408_residues
MSALPPPRFNPFDSEFRQDPYRVYAHLRVAAPIHRSLGMWVLTRYADVLAVLKDPHFSSSQIPLAVRQRSERPDQAQSHP
LARLAAKSIVFTDEPDHTRLRHLVVRAIKRRTPEQEQAHLTRIASALLERVGPKGRMDAVADYAERLPLQFMAESMALPP
DSWQTVRDWTHQLRYLLEPGLMGRGDFERVQAVLDEVIAFFEDMLAVRRQQPGDDLISALDAAHREAQADRLSDEEIVYC
CIMMFVAGHETTRSLIASGLLALLQHPEQLAYLRMHPERMGAAVTEMLRYESPLQQTKRRATAAVAVGGRTIQPQEQVLL
CLGAANRDPARFEQPDRFDITRTDNGHLAFGQGMHHCLGAALAQMEAQVALRVLLERFANLTLQDTPEWLEHSFILRGLK
TLPVQWDR
>Mature_407_residues
SALPPPRFNPFDSEFRQDPYRVYAHLRVAAPIHRSLGMWVLTRYADVLAVLKDPHFSSSQIPLAVRQRSERPDQAQSHPL
ARLAAKSIVFTDEPDHTRLRHLVVRAIKRRTPEQEQAHLTRIASALLERVGPKGRMDAVADYAERLPLQFMAESMALPPD
SWQTVRDWTHQLRYLLEPGLMGRGDFERVQAVLDEVIAFFEDMLAVRRQQPGDDLISALDAAHREAQADRLSDEEIVYCC
IMMFVAGHETTRSLIASGLLALLQHPEQLAYLRMHPERMGAAVTEMLRYESPLQQTKRRATAAVAVGGRTIQPQEQVLLC
LGAANRDPARFEQPDRFDITRTDNGHLAFGQGMHHCLGAALAQMEAQVALRVLLERFANLTLQDTPEWLEHSFILRGLKT
LPVQWDR

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46344; Mature: 46213

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SALPPPRFNPFDSEFRQDPYRVYAHLRVAAPIHRSLGMWVLTRYADVLAVLKDPHFSSS
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QIPLAVRQRSERPDQAQSHPLARLAAKSIVFTDEPDHTRLRHLVVRAIKRRTPEQEQAHL
CCCHHHHHCCCCCCHHHHCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
TRIASALLERVGPKGRMDAVADYAERLPLQFMAESMALPPDSWQTVRDWTHQLRYLLEPG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
LMGRGDFERVQAVLDEVIAFFEDMLAVRRQQPGDDLISALDAAHREAQADRLSDEEIVYC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
CIMMFVAGHETTRSLIASGLLALLQHPEQLAYLRMHPERMGAAVTEMLRYESPLQQTKRR
HHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHH
ATAAVAVGGRTIQPQEQVLLCLGAANRDPARFEQPDRFDITRTDNGHLAFGQGMHHCLGA
HHHHHEECCCCCCCHHHHEEHCCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHH
ALAQMEAQVALRVLLERFANLTLQDTPEWLEHSFILRGLKTLPVQWDR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]