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The map label for this gene is grsT [H]

Identifier: 37521503

GI number: 37521503

Start: 2057662

End: 2058450

Strand: Reverse

Name: grsT [H]

Synonym: gll1934

Alternate gene names: 37521503

Gene position: 2058450-2057662 (Counterclockwise)

Preceding gene: 37521504

Following gene: 37521500

Centisome position: 44.18

GC content: 63.12

Gene sequence:

>789_bases
ATGAATTTACCGAACAATCATCTCGGCAGTGCACCGTATTTTGCGGCGGCGGAGTGGTTCCGCTGGTGTACACCCAACCC
GGGCGCACGGCTGCGTTTATTCTGTTTTCCCCACGCGGGCTGCGGCGCGTCGGTCTACCGCGAATGGCGCACAGGGCTGC
CGGAGGCGATCGAAGTGCGGCCCTGCCAGTTGCCCGGCCGCGAAAATCTGACCCGCTTGCCGATGCCTCTGCGCTTGCCC
GAATTGATCGACGCATTGGTCTCAGTTCTTGTACCGCACCTTGATCGTCCTTTTGCCTTCTTTGGGCACAGCATGGGAGC
CCTGGTCAGTTTCGAGCTGGCGCGGCAGTTGCGGCGGCAACATCTGCCGCTGCCGGTCTGTTTGCTGGTGGCCAGCCGCC
GAGCGCCGCAGCTGACCTCCCCGATGCCCGCCAGCGATTTGCTGTCGGAGGAGGCACTACTTGCCTGGGTGCGCAAAGTC
GGCGGTACCCCCGAAGCCCTGCTGGCCCACCCGAAGTGGCGGGAGCACTACCTGGGCATTTTGCGGGCCGATTTGCGATT
GACTGAGCACTATCTCTACCGGCCGGAACCGCCGCTAGGTTGTCCGGTATTCGCCTACGGCGGAACGCACGACACGGTGG
TCACCCACCCACAGCTTGCGGCCTGGCGCGAACAGACCGCAAGCGCCTTTACTCTGCAGATGCTCCCGGGGGGCCATATT
TTTGACCCGCCCATGGTGCAGCAGCAGCTTGCCAGTATGGCCGACCGCCTCGGCTCTTTTTTGATCTGA

Upstream 100 bases:

>100_bases
TGGAGCGTTTTGCCAACCTGACGTTACAGGATACCCCCGAGTGGTTGGAGCACAGCTTCATCCTGCGGGGACTGAAGACA
CTTCCCGTGCAATGGGACCG

Downstream 100 bases:

>100_bases
AGTAACGTCAGCTCGGGTGCAACTGCTCCTGCTCAGCGCTTTGCAGCCGTAATTTTAAGGATGAATACTCCCGTCGGGCA
TCGTCGCCCTGCCCAGCAGC

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNLPNNHLGSAPYFAAAEWFRWCTPNPGARLRLFCFPHAGCGASVYREWRTGLPEAIEVRPCQLPGRENLTRLPMPLRLP
ELIDALVSVLVPHLDRPFAFFGHSMGALVSFELARQLRRQHLPLPVCLLVASRRAPQLTSPMPASDLLSEEALLAWVRKV
GGTPEALLAHPKWREHYLGILRADLRLTEHYLYRPEPPLGCPVFAYGGTHDTVVTHPQLAAWREQTASAFTLQMLPGGHI
FDPPMVQQQLASMADRLGSFLI

Sequences:

>Translated_262_residues
MNLPNNHLGSAPYFAAAEWFRWCTPNPGARLRLFCFPHAGCGASVYREWRTGLPEAIEVRPCQLPGRENLTRLPMPLRLP
ELIDALVSVLVPHLDRPFAFFGHSMGALVSFELARQLRRQHLPLPVCLLVASRRAPQLTSPMPASDLLSEEALLAWVRKV
GGTPEALLAHPKWREHYLGILRADLRLTEHYLYRPEPPLGCPVFAYGGTHDTVVTHPQLAAWREQTASAFTLQMLPGGHI
FDPPMVQQQLASMADRLGSFLI
>Mature_262_residues
MNLPNNHLGSAPYFAAAEWFRWCTPNPGARLRLFCFPHAGCGASVYREWRTGLPEAIEVRPCQLPGRENLTRLPMPLRLP
ELIDALVSVLVPHLDRPFAFFGHSMGALVSFELARQLRRQHLPLPVCLLVASRRAPQLTSPMPASDLLSEEALLAWVRKV
GGTPEALLAHPKWREHYLGILRADLRLTEHYLYRPEPPLGCPVFAYGGTHDTVVTHPQLAAWREQTASAFTLQMLPGGHI
FDPPMVQQQLASMADRLGSFLI

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=227, Percent_Identity=30.3964757709251, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI8922871, Length=280, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 29330; Mature: 29330

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNNHLGSAPYFAAAEWFRWCTPNPGARLRLFCFPHAGCGASVYREWRTGLPEAIEVR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEC
PCQLPGRENLTRLPMPLRLPELIDALVSVLVPHLDRPFAFFGHSMGALVSFELARQLRRQ
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HLPLPVCLLVASRRAPQLTSPMPASDLLSEEALLAWVRKVGGTPEALLAHPKWREHYLGI
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
LRADLRLTEHYLYRPEPPLGCPVFAYGGTHDTVVTHPQLAAWREQTASAFTLQMLPGGHI
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCC
FDPPMVQQQLASMADRLGSFLI
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLPNNHLGSAPYFAAAEWFRWCTPNPGARLRLFCFPHAGCGASVYREWRTGLPEAIEVR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEC
PCQLPGRENLTRLPMPLRLPELIDALVSVLVPHLDRPFAFFGHSMGALVSFELARQLRRQ
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
HLPLPVCLLVASRRAPQLTSPMPASDLLSEEALLAWVRKVGGTPEALLAHPKWREHYLGI
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
LRADLRLTEHYLYRPEPPLGCPVFAYGGTHDTVVTHPQLAAWREQTASAFTLQMLPGGHI
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCC
FDPPMVQQQLASMADRLGSFLI
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]