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The map label for this gene is pcaA [H]

Identifier: 37521505

GI number: 37521505

Start: 2059670

End: 2060560

Strand: Reverse

Name: pcaA [H]

Synonym: gll1936

Alternate gene names: 37521505

Gene position: 2060560-2059670 (Counterclockwise)

Preceding gene: 37521506

Following gene: 37521504

Centisome position: 44.23

GC content: 64.09

Gene sequence:

>891_bases
GTGAGTGTGCTGCGCGGTCCAAACCGCGGCGGTTCACCTGAAGCCATTCGCCACCATTACGACCTGAGCAATGCCTTCTA
CAGCCTCTGGCTGGACGAATCGATGACCTACTCCTGCGCCCTGTGGGAAGCCGAAGCCCCCGAGGCGCCTTTGGCTGTTG
CCCAACAGCGAAAGCTCGACTTCCACCTGCGCGCCGCCCGGGCGACGGGCGCCGCCCGGGCGCTCGATATCGGCTGCGGT
TGGGGAGCGCTGCTCAGACGGATGAGGGAGGACTTTGGCGTCGCCCAGGCCGTCGGGTTGACGCTGAGCGAAGCGCAAGC
CGAACATGTCCGCTCCCTGGGGCTCAGCGGCGTCGAGGTGCGTACCGAAAGCTGGACGGCGCATACCCCGGCTGCCACCT
ACGACGCCATCGTCTCGATCGGCGCTTTTGAGCATTTTGCCCAACCGGAGCAAGCGAGCGACCAGAAAATCGAGATCTAC
CGCGCTTTTTTCGAGCGCTGCTGCCGGTGGCTTGCCGGTTCGGGGCGATTGTCTTTGCAGACGATCGCCTACGGAACGCT
GCGCCCGGAGGCGGCGAGCCGCTTTATTCAAACCGAAATCTTTCCCGATTCGGAATTGCCGCATCTGGGCGAAATCGTCG
CCGCCTGCGAAGGTCTGTTTGAGATTGTCCTGTTGCGCAACGACCGGCTGGACTATGCCCGCACCTGCGAGGCGTGGCTT
GCCCGCCTGCGTGCCCGGCGGGGCGAGGCCCTCACTCTGGTGGGAGAGGCGGCGGTCGAGCGCTACGAACGCTATTTAAA
AATGTCGTCGGTCGGCTTTCGCATGGGCAAAATCGGCCTGTTGCGCCTGGTGCTCGAACCGATCCGTTCGCGCTGGCACC
GTGCGTCATGA

Upstream 100 bases:

>100_bases
TGTCGCCGGCGCTGCTGTTTGAGTATCCGACGATCGACTCTATGGCTGAACATCTTTACCACCAGAAACGGCAGGCAGCC
TTGACCCAACCGGTGCAGCC

Downstream 100 bases:

>100_bases
GTGCCCTGCCACCGCCCCGGTTCAATCCTTTCGATTCTGAGTTTCGCCAAGACCCCTACCGCGTCTACGCGCATCTGCGG
GTGGCCGCTCCTATCCACCG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CMAS; Cyclopropane-fatty-acyl-phospholipid synthase; CFA synthase; Cyclopropane fatty acid synthase; Mycolic acid methyltransferase; MA-MT; S-adenosylmethionine-dependent methyltransferase; AdoMet-MT; SAM-MT [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSVLRGPNRGGSPEAIRHHYDLSNAFYSLWLDESMTYSCALWEAEAPEAPLAVAQQRKLDFHLRAARATGAARALDIGCG
WGALLRRMREDFGVAQAVGLTLSEAQAEHVRSLGLSGVEVRTESWTAHTPAATYDAIVSIGAFEHFAQPEQASDQKIEIY
RAFFERCCRWLAGSGRLSLQTIAYGTLRPEAASRFIQTEIFPDSELPHLGEIVAACEGLFEIVLLRNDRLDYARTCEAWL
ARLRARRGEALTLVGEAAVERYERYLKMSSVGFRMGKIGLLRLVLEPIRSRWHRAS

Sequences:

>Translated_296_residues
MSVLRGPNRGGSPEAIRHHYDLSNAFYSLWLDESMTYSCALWEAEAPEAPLAVAQQRKLDFHLRAARATGAARALDIGCG
WGALLRRMREDFGVAQAVGLTLSEAQAEHVRSLGLSGVEVRTESWTAHTPAATYDAIVSIGAFEHFAQPEQASDQKIEIY
RAFFERCCRWLAGSGRLSLQTIAYGTLRPEAASRFIQTEIFPDSELPHLGEIVAACEGLFEIVLLRNDRLDYARTCEAWL
ARLRARRGEALTLVGEAAVERYERYLKMSSVGFRMGKIGLLRLVLEPIRSRWHRAS
>Mature_295_residues
SVLRGPNRGGSPEAIRHHYDLSNAFYSLWLDESMTYSCALWEAEAPEAPLAVAQQRKLDFHLRAARATGAARALDIGCGW
GALLRRMREDFGVAQAVGLTLSEAQAEHVRSLGLSGVEVRTESWTAHTPAATYDAIVSIGAFEHFAQPEQASDQKIEIYR
AFFERCCRWLAGSGRLSLQTIAYGTLRPEAASRFIQTEIFPDSELPHLGEIVAACEGLFEIVLLRNDRLDYARTCEAWLA
RLRARRGEALTLVGEAAVERYERYLKMSSVGFRMGKIGLLRLVLEPIRSRWHRAS

Specific function: Catalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfers of a methylene group from S-adenosyl-L- methionine. Cyclopropanated mycolic acids are key factors participating in cell en

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=270, Percent_Identity=30.7407407407407, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI133904226, Length=291, Percent_Identity=28.1786941580756, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 33097; Mature: 32966

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLRGPNRGGSPEAIRHHYDLSNAFYSLWLDESMTYSCALWEAEAPEAPLAVAQQRKLD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHH
FHLRAARATGAARALDIGCGWGALLRRMREDFGVAQAVGLTLSEAQAEHVRSLGLSGVEV
HHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCCCCCEEE
RTESWTAHTPAATYDAIVSIGAFEHFAQPEQASDQKIEIYRAFFERCCRWLAGSGRLSLQ
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
TIAYGTLRPEAASRFIQTEIFPDSELPHLGEIVAACEGLFEIVLLRNDRLDYARTCEAWL
EEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARLRARRGEALTLVGEAAVERYERYLKMSSVGFRMGKIGLLRLVLEPIRSRWHRAS
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVLRGPNRGGSPEAIRHHYDLSNAFYSLWLDESMTYSCALWEAEAPEAPLAVAQQRKLD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHH
FHLRAARATGAARALDIGCGWGALLRRMREDFGVAQAVGLTLSEAQAEHVRSLGLSGVEV
HHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCCCCCEEE
RTESWTAHTPAATYDAIVSIGAFEHFAQPEQASDQKIEIYRAFFERCCRWLAGSGRLSLQ
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
TIAYGTLRPEAASRFIQTEIFPDSELPHLGEIVAACEGLFEIVLLRNDRLDYARTCEAWL
EEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARLRARRGEALTLVGEAAVERYERYLKMSSVGFRMGKIGLLRLVLEPIRSRWHRAS
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]