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The map label for this gene is cobL [H]

Identifier: 37519947

GI number: 37519947

Start: 395058

End: 396287

Strand: Reverse

Name: cobL [H]

Synonym: gvip029

Alternate gene names: 37519947

Gene position: 396287-395058 (Counterclockwise)

Preceding gene: 37519948

Following gene: 37519946

Centisome position: 8.51

GC content: 68.54

Gene sequence:

>1230_bases
ATGCACCTGCTTTCCATCGTGGGCATCGGAGCGGACGGTCCCCGCGGACTGTCGGCGGACACCCAGGCCCTCATCGCCCA
GAGCCCGGTGATCGCCGGAAGTGCCGAGCAGTTGCGCTGGTGGCCGGGGCGCAGTGGGCGGATCGAAATGGGCGCCGATC
TGGCCGCTTTTTTTGCGCAACTGGAGCAGGCGCTCACCGAGGCACCGGTGGTGTTGGTGGCGACCGGCGACCCGCTCTAC
TTCGGGATTGGACGGCTGGTGCTCGAACGGTTCGGCCGGGAGCAGGTGCGCTTTATGCCGCACCTCAGCTCGGTGCAACT
GGCCTGCAGCCGGGCGAAGCTCCCCTGGCAGGAGGCAGCGGTGGTGAGCGCCCACGGCCGCTCCCTCGAAAAGCTCGGCG
AGGCCCTGCGCCCGCTTCCCGAACTGGTCGCGGTACTCACCGACCCGGTCAACACCCCGGCGCGCATCGCCCGCTTCGTG
CTGGATCTCGCCCCGGTGACCCCGTACCGGCTGTGGGTGTGCGCCCGGCTCGGCGCCGAGGACGAGCAGGTCGAATGCCT
GGGCTGCGAGCAAGCCTGCGAGCGGGATTTTGGCGAGCCGAACGTGGTGCTGCTGGAGCGCGCCCCCGCCCGCACCCCGG
CCAGTCTGCCCGCCGTGGGCATCTTCGACGATCACTTCGTCACTTTTTCGGACAAACCCGGCCTGATGACCAAGTACGAA
GTGCGGGTTCTGGCGATTGCTTATCTGCAACTGGAGCGTGGGCAGGTCTGCTGGGATATCGGCAGCGGCACCGGCTCGGT
GGCGATCGAAATGGCCCGCCTGATCGGCGGCGGCAGCGTCTACGCGATTGAAAAGACCGAGGCGGGCTGTCTGCTCATCG
AGGCCAACTGTGCCCGCCTCGGGGTGTGCAACGTGCGGGTGCGCCGCGCCCGCGCCCCGGAGGTGCTCGCTGAACTGCCC
GCCCCGGATCGGATCTTTTTGGGCGGCGGCGGACGCCAATTGGTGGCCATCCTCGAAGCCTGCACCGCCGGGCTGCGCCC
GGGCGGGATCCTGGTGGCCAGTTTCGCCGGGCTCGAGCAACTGGTGAGCGCCCAGGCTTACTTGCTCAAGCAGGGCTGGT
CCGTGCAGTACACCCATCTGCAGATTGCCCGCTCGGCGAGCCTTGCGAGCGGTTCGCGGCTGGTGCCCCTCAATCCGGTC
TTTTTGTTGCGCTCCACCCGGCCCCTGTGA

Upstream 100 bases:

>100_bases
CCAGGCAGCCATCCTGGCCCTTCAGGAGGGGTTGATGGACCGGTAGATCGGTGGATGGCGGTGTTATACTCGCCGCGTTC
CGGGAGGCTCGGTACGGCTT

Downstream 100 bases:

>100_bases
ACCTCGGCACACTCTACGGCATCGGCGTCGGCCCGGGCGATCCGGAACTCCTCACCCTCAAGGGTCTGCGGGTGCTGCGC
TCGGCGGCGGTGGTGGCCTG

Product: precorrin-6Y methylase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MHLLSIVGIGADGPRGLSADTQALIAQSPVIAGSAEQLRWWPGRSGRIEMGADLAAFFAQLEQALTEAPVVLVATGDPLY
FGIGRLVLERFGREQVRFMPHLSSVQLACSRAKLPWQEAAVVSAHGRSLEKLGEALRPLPELVAVLTDPVNTPARIARFV
LDLAPVTPYRLWVCARLGAEDEQVECLGCEQACERDFGEPNVVLLERAPARTPASLPAVGIFDDHFVTFSDKPGLMTKYE
VRVLAIAYLQLERGQVCWDIGSGTGSVAIEMARLIGGGSVYAIEKTEAGCLLIEANCARLGVCNVRVRRARAPEVLAELP
APDRIFLGGGGRQLVAILEACTAGLRPGGILVASFAGLEQLVSAQAYLLKQGWSVQYTHLQIARSASLASGSRLVPLNPV
FLLRSTRPL

Sequences:

>Translated_409_residues
MHLLSIVGIGADGPRGLSADTQALIAQSPVIAGSAEQLRWWPGRSGRIEMGADLAAFFAQLEQALTEAPVVLVATGDPLY
FGIGRLVLERFGREQVRFMPHLSSVQLACSRAKLPWQEAAVVSAHGRSLEKLGEALRPLPELVAVLTDPVNTPARIARFV
LDLAPVTPYRLWVCARLGAEDEQVECLGCEQACERDFGEPNVVLLERAPARTPASLPAVGIFDDHFVTFSDKPGLMTKYE
VRVLAIAYLQLERGQVCWDIGSGTGSVAIEMARLIGGGSVYAIEKTEAGCLLIEANCARLGVCNVRVRRARAPEVLAELP
APDRIFLGGGGRQLVAILEACTAGLRPGGILVASFAGLEQLVSAQAYLLKQGWSVQYTHLQIARSASLASGSRLVPLNPV
FLLRSTRPL
>Mature_409_residues
MHLLSIVGIGADGPRGLSADTQALIAQSPVIAGSAEQLRWWPGRSGRIEMGADLAAFFAQLEQALTEAPVVLVATGDPLY
FGIGRLVLERFGREQVRFMPHLSSVQLACSRAKLPWQEAAVVSAHGRSLEKLGEALRPLPELVAVLTDPVNTPARIARFV
LDLAPVTPYRLWVCARLGAEDEQVECLGCEQACERDFGEPNVVLLERAPARTPASLPAVGIFDDHFVTFSDKPGLMTKYE
VRVLAIAYLQLERGQVCWDIGSGTGSVAIEMARLIGGGSVYAIEKTEAGCLLIEANCARLGVCNVRVRRARAPEVLAELP
APDRIFLGGGGRQLVAILEACTAGLRPGGILVASFAGLEQLVSAQAYLLKQGWSVQYTHLQIARSASLASGSRLVPLNPV
FLLRSTRPL

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43886; Mature: 43886

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLLSIVGIGADGPRGLSADTQALIAQSPVIAGSAEQLRWWPGRSGRIEMGADLAAFFAQ
CCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHEEECCCCCCCEEECCHHHHHHHH
LEQALTEAPVVLVATGDPLYFGIGRLVLERFGREQVRFMPHLSSVQLACSRAKLPWQEAA
HHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCCHHHHH
VVSAHGRSLEKLGEALRPLPELVAVLTDPVNTPARIARFVLDLAPVTPYRLWVCARLGAE
EEECCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEEEEHHCCCC
DEQVECLGCEQACERDFGEPNVVLLERAPARTPASLPAVGIFDDHFVTFSDKPGLMTKYE
CCCEEEECHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCHHH
VRVLAIAYLQLERGQVCWDIGSGTGSVAIEMARLIGGGSVYAIEKTEAGCLLIEANCARL
HEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEE
GVCNVRVRRARAPEVLAELPAPDRIFLGGGGRQLVAILEACTAGLRPGGILVASFAGLEQ
EEEEEEEECCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
LVSAQAYLLKQGWSVQYTHLQIARSASLASGSRLVPLNPVFLLRSTRPL
HHHHHHHHHHCCCCEEEEEEEEEHHCCCCCCCEEECCCCEEEEECCCCC
>Mature Secondary Structure
MHLLSIVGIGADGPRGLSADTQALIAQSPVIAGSAEQLRWWPGRSGRIEMGADLAAFFAQ
CCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHEEECCCCCCCEEECCHHHHHHHH
LEQALTEAPVVLVATGDPLYFGIGRLVLERFGREQVRFMPHLSSVQLACSRAKLPWQEAA
HHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCCHHHHH
VVSAHGRSLEKLGEALRPLPELVAVLTDPVNTPARIARFVLDLAPVTPYRLWVCARLGAE
EEECCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEEEEHHCCCC
DEQVECLGCEQACERDFGEPNVVLLERAPARTPASLPAVGIFDDHFVTFSDKPGLMTKYE
CCCEEEECHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEECCCCCCCCHHH
VRVLAIAYLQLERGQVCWDIGSGTGSVAIEMARLIGGGSVYAIEKTEAGCLLIEANCARL
HEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEE
GVCNVRVRRARAPEVLAELPAPDRIFLGGGGRQLVAILEACTAGLRPGGILVASFAGLEQ
EEEEEEEECCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
LVSAQAYLLKQGWSVQYTHLQIARSASLASGSRLVPLNPVFLLRSTRPL
HHHHHHHHHHCCCCEEEEEEEEEHHCCCCCCCEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]