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The map label for this gene is cobI [H]

Identifier: 37519946

GI number: 37519946

Start: 394342

End: 395061

Strand: Reverse

Name: cobI [H]

Synonym: gvip028

Alternate gene names: 37519946

Gene position: 395061-394342 (Counterclockwise)

Preceding gene: 37519947

Following gene: 37519941

Centisome position: 8.48

GC content: 65.42

Gene sequence:

>720_bases
GTGAACCTCGGCACACTCTACGGCATCGGCGTCGGCCCGGGCGATCCGGAACTCCTCACCCTCAAGGGTCTGCGGGTGCT
GCGCTCGGCGGCGGTGGTGGCCTGCCCCGCGGACCGCACGGGCCGGCCCGGCCTGGCAGCCCGGATCGCAGCCCCCCATC
TGCGTCGCGAGCAGCGCCTTACACCGCTCTATTTACCCTTCGTTTCGGATGAGGCGGTGCTCGCGGCAGCCTGGAGCGCA
GCCGCCGATACGCTCTACGCGGATCTGGCGCTGGGCTTGGATGTCGCCTTTATCAGCGAGGGTGATGTCAGTTTGTTCAG
CACCTTCACCTATATCCTTCGGGAGTTCCAGGAGCGCTACGCCCAGGTTGCCGTCCGGATCATCCCCGGCATCGCCTCAC
CGCTGGCCGCCGCCGCCGCTTTGCAATTGCCCCTCGCAATCGGCGATGAAACCCTGACTATCCTGCCTGCCATGCACCGC
ATTGAGGAGTTGGAAGCCGCCTGCGCCCCCGGTCGCATCGTCGTGCTGCTCAAAGTCGCTCCGGTGTACGAGCAAGTTTA
TACATGGCTCAAGGCATCGGACCGCCTGGAGCAGGCCCACCTGCTCTGCTGGGTAAGCGCAAAGGAAGAGCGGATCTACC
GGCGGCTGCCCGCTGCGGCCGAACGGCTGCCCTATTTTTCGTTGCTGATTATCCGCCCAGAGCCGGCAGCTCGACGGTAA

Upstream 100 bases:

>100_bases
AGTACACCCATCTGCAGATTGCCCGCTCGGCGAGCCTTGCGAGCGGTTCGCGGCTGGTGCCCCTCAATCCGGTCTTTTTG
TTGCGCTCCACCCGGCCCCT

Downstream 100 bases:

>100_bases
AAACGGCCCCTTTGCCCTCGCCCTCGCTCTCGGCTTGGACCATTCCCCCGTGCAATTCGACGATGTGGCGCACGATGAAC
AATCCCAGCCCCAATCCTCC

Product: precorrin-2 methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNLGTLYGIGVGPGDPELLTLKGLRVLRSAAVVACPADRTGRPGLAARIAAPHLRREQRLTPLYLPFVSDEAVLAAAWSA
AADTLYADLALGLDVAFISEGDVSLFSTFTYILREFQERYAQVAVRIIPGIASPLAAAAALQLPLAIGDETLTILPAMHR
IEELEAACAPGRIVVLLKVAPVYEQVYTWLKASDRLEQAHLLCWVSAKEERIYRRLPAAAERLPYFSLLIIRPEPAARR

Sequences:

>Translated_239_residues
MNLGTLYGIGVGPGDPELLTLKGLRVLRSAAVVACPADRTGRPGLAARIAAPHLRREQRLTPLYLPFVSDEAVLAAAWSA
AADTLYADLALGLDVAFISEGDVSLFSTFTYILREFQERYAQVAVRIIPGIASPLAAAAALQLPLAIGDETLTILPAMHR
IEELEAACAPGRIVVLLKVAPVYEQVYTWLKASDRLEQAHLLCWVSAKEERIYRRLPAAAERLPYFSLLIIRPEPAARR
>Mature_239_residues
MNLGTLYGIGVGPGDPELLTLKGLRVLRSAAVVACPADRTGRPGLAARIAAPHLRREQRLTPLYLPFVSDEAVLAAAWSA
AADTLYADLALGLDVAFISEGDVSLFSTFTYILREFQERYAQVAVRIIPGIASPLAAAAALQLPLAIGDETLTILPAMHR
IEELEAACAPGRIVVLLKVAPVYEQVYTWLKASDRLEQAHLLCWVSAKEERIYRRLPAAAERLPYFSLLIIRPEPAARR

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26051; Mature: 26051

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGTLYGIGVGPGDPELLTLKGLRVLRSAAVVACPADRTGRPGLAARIAAPHLRREQRL
CCCCEEEEECCCCCCCCEEEHHHHHHHHHHHEEECCCCCCCCCCHHHHHHCHHHHHHHCC
TPLYLPFVSDEAVLAAAWSAAADTLYADLALGLDVAFISEGDVSLFSTFTYILREFQERY
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHH
AQVAVRIIPGIASPLAAAAALQLPLAIGDETLTILPAMHRIEELEAACAPGRIVVLLKVA
HHHHHHHHCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
PVYEQVYTWLKASDRLEQAHLLCWVSAKEERIYRRLPAAAERLPYFSLLIIRPEPAARR
HHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MNLGTLYGIGVGPGDPELLTLKGLRVLRSAAVVACPADRTGRPGLAARIAAPHLRREQRL
CCCCEEEEECCCCCCCCEEEHHHHHHHHHHHEEECCCCCCCCCCHHHHHHCHHHHHHHCC
TPLYLPFVSDEAVLAAAWSAAADTLYADLALGLDVAFISEGDVSLFSTFTYILREFQERY
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHH
AQVAVRIIPGIASPLAAAAALQLPLAIGDETLTILPAMHRIEELEAACAPGRIVVLLKVA
HHHHHHHHCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
PVYEQVYTWLKASDRLEQAHLLCWVSAKEERIYRRLPAAAERLPYFSLLIIRPEPAARR
HHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]