Click here to switch to the map view.

The map label for this gene is mogA [H]

Identifier: 34498654

GI number: 34498654

Start: 3482907

End: 3483485

Strand: Direct

Name: mogA [H]

Synonym: CV_3199

Alternate gene names: 34498654

Gene position: 3482907-3483485 (Clockwise)

Preceding gene: 34498653

Following gene: 34498655

Centisome position: 73.31

GC content: 69.43

Gene sequence:

>579_bases
ATGCTGAAGATAGGCCTGGTTTCCATTTCCGACCGCGCCAGCCAAGGCGTGTACGAGGACAAGGGCCTGCCCGCGCTGCG
GGAATGGCTGGCGCGCGCGATCGCCACGCCGTTCGAAACCGTCAGCCGGCTGATCCCCGACGAGCAGCCGGGCATCGAGG
CCGCGCTGAAGGCGCTGGTCGACGACGAGGGTTGCCAGCTGGTGCTGACCACCGGCGGCACCGGCCCGGCGCCGCGCGAC
GTGACGCCGGACGCCACGCTGGCGGTGGCCGACCGGGAAATGCCCGGTTTCGGCGAACAGATGCGCCAGATCAGCCTGCG
CTTCGTCCCCACCGCCATCCTGTCGCGCCAGGTCGGCGTGATCCGCAAGCAGAGCCTGATCCTGAACCTGCCCGGCCAGC
CCAAGGCGATCCAGGAAACGCTGGAAGGCCTGCGCGGGGCCGACGGCAAGGTGGAGGTGCCCGGCATCTTCGCCGCCGTG
CCCTACTGCCTGGACCTAATCGGCGCGCCCTACATCGAAACCGATGAAGCGGTGGTCAAGGCCTTCCGGCCCAAGTCCGC
CGTCAAGCCGGCGCCATGA

Upstream 100 bases:

>100_bases
AACCGCCCAAGGCCTACCGCCAATTGTTCCAGGAAATCAAGGCGCTGATCCCGGAGCCGGGCAAGCCGCGGCTGTGGCAA
AAGGACGAGGACGAAGAATA

Downstream 100 bases:

>100_bases
GCTACCGCGCGCCGCGCTGGCTGCGGGGCGGCCACGCGCAAACCATCTGGCCGGCGCTGGCGGTCAAGCAGGACGCGCCG
TCCTACCGCCGCGAGCTGTG

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLKIGLVSISDRASQGVYEDKGLPALREWLARAIATPFETVSRLIPDEQPGIEAALKALVDDEGCQLVLTTGGTGPAPRD
VTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQVGVIRKQSLILNLPGQPKAIQETLEGLRGADGKVEVPGIFAAV
PYCLDLIGAPYIETDEAVVKAFRPKSAVKPAP

Sequences:

>Translated_192_residues
MLKIGLVSISDRASQGVYEDKGLPALREWLARAIATPFETVSRLIPDEQPGIEAALKALVDDEGCQLVLTTGGTGPAPRD
VTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQVGVIRKQSLILNLPGQPKAIQETLEGLRGADGKVEVPGIFAAV
PYCLDLIGAPYIETDEAVVKAFRPKSAVKPAP
>Mature_192_residues
MLKIGLVSISDRASQGVYEDKGLPALREWLARAIATPFETVSRLIPDEQPGIEAALKALVDDEGCQLVLTTGGTGPAPRD
VTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQVGVIRKQSLILNLPGQPKAIQETLEGLRGADGKVEVPGIFAAV
PYCLDLIGAPYIETDEAVVKAFRPKSAVKPAP

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=176, Percent_Identity=33.5227272727273, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI66932975, Length=176, Percent_Identity=33.5227272727273, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1786190, Length=186, Percent_Identity=75.8064516129032, Blast_Score=286, Evalue=7e-79,
Organism=Escherichia coli, GI1787000, Length=144, Percent_Identity=31.25, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=146, Percent_Identity=37.6712328767123, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136978, Length=191, Percent_Identity=32.4607329842932, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638841, Length=191, Percent_Identity=32.4607329842932, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20482; Mature: 20482

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGLVSISDRASQGVYEDKGLPALREWLARAIATPFETVSRLIPDEQPGIEAALKALV
CEEEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHH
DDEGCQLVLTTGGTGPAPRDVTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQVGV
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRKQSLILNLPGQPKAIQETLEGLRGADGKVEVPGIFAAVPYCLDLIGAPYIETDEAVVK
HHHCEEEEECCCCCHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCCCCCHHHHHH
AFRPKSAVKPAP
HHCCCCCCCCCC
>Mature Secondary Structure
MLKIGLVSISDRASQGVYEDKGLPALREWLARAIATPFETVSRLIPDEQPGIEAALKALV
CEEEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHH
DDEGCQLVLTTGGTGPAPRDVTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQVGV
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRKQSLILNLPGQPKAIQETLEGLRGADGKVEVPGIFAAVPYCLDLIGAPYIETDEAVVK
HHHCEEEEECCCCCHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCCCCCHHHHHH
AFRPKSAVKPAP
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]