Click here to switch to the map view.

The map label for this gene is yiaY [H]

Identifier: 34498183

GI number: 34498183

Start: 2957286

End: 2958419

Strand: Reverse

Name: yiaY [H]

Synonym: CV_2728

Alternate gene names: 34498183

Gene position: 2958419-2957286 (Counterclockwise)

Preceding gene: 34498184

Following gene: 34498182

Centisome position: 62.27

GC content: 66.84

Gene sequence:

>1134_bases
ATGAGCACAAGCGCTTTCTTCATCCCCTCGCTGAACCTGATGGGCGCGGGCTGTCTGCAACAGGCCGTCGACGCGATGCG
CGGCCACGGTTTCCGCCGCGCGCTGATCGTCACCGACCAGGGCCTGGTCAAGGCCGGCCTGGCCGCCAAGGTGGCCGACA
TGCTGGGCAAGGCCGACATCGAACCGGTGATCTTCGACGGCGTCCATCCCAATCCCAGCTGCGCCAATGTCAACGCCGGT
CTGGCGCTGCTCAAGGAAAAGCAGTGCGACGTGGTGGTGTCGCTGGGCGGCGGCTCGCCGCACGACTGCGCCAAAGGCAT
CGCGCTGGTGGCGGTGAACGGCGGCAAGATCCAGGACTACGAGGGCGTGGACAAGTCGGCCAAGCCGCAGCTGCCGCTGG
TGGCGATCAACACCACCGCAGGCACCGCGTCCGAAATGACCCGCTTCTGCATCATCACCGACGAGTCGCGCCATATCAAG
ATGGCCATCGTCGACAAGCACACCACGCCCATCCTGTCGGTCAACGATCCGGAAACCATGGCCGGCATGCCGGCCTCGCT
GACCGCCGCCACCGGCATGGACGCGCTGACCCACGCGGTGGAAGCCTATGTGTCCACTATCGCCACCCCCATCACCGACG
CCTGCGCCTTGAAGGCGGTGGAACTGATCGCCGGCTTCCTGCGCCGCGCGGTGAAGGACGGCAAGGACATGGAAGCGCGC
GAGCAAATGGCTTACGCCCAGTTCCTGGCCGGCATGGCCTTCAACAACGCCTCGCTGGGCTATGTGCACGCGATGGCGCA
CCAGCTGGGCGGCTTCTACGACCTGCCGCACGGCGTGTGCAACGCGGTGCTGCTGCCGCATGTGCAGGCCTTCAACGCAG
CCTCGGCCGGAGAGCGGCTGGGCGACGTGGCCATCGCGCTGGGCGAGAAGACACGCAGCGCCCAGGCGGCCATCGCGGCG
ATCAAGCGCCTGGCGGCGGATGTCGGCATTCCGGCAGGCTTGAGGGAGCTGGGCGTCAAGGAGGCGGATATCCCGACGCT
GGCGGACAACGCGCTGAAGGATGCCTGCGGTTTCACCAATCCGCGCAAGGGCAGCCATGAGGATGTCTGCGCGATCTTCC
GCGCCGCGATGTAG

Upstream 100 bases:

>100_bases
TTGCCGCTTGGCCGGCATTTATTGACTTGAGGCAAAGTTGACGGGAGGAGGAGAAGGCGGCAGACTGTGTTCAATGGGAA
TCCACCGACTGGAGACGGAT

Downstream 100 bases:

>100_bases
CGGGAGCGGGAAGGCGGCGCGGCGGATGTCACCCATCCGCCGCGCAGGGATAAATTTTTTTGCCGTCATATATCGCACTG
CGATATTTTAATTAAAAGCT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSTSAFFIPSLNLMGAGCLQQAVDAMRGHGFRRALIVTDQGLVKAGLAAKVADMLGKADIEPVIFDGVHPNPSCANVNAG
LALLKEKQCDVVVSLGGGSPHDCAKGIALVAVNGGKIQDYEGVDKSAKPQLPLVAINTTAGTASEMTRFCIITDESRHIK
MAIVDKHTTPILSVNDPETMAGMPASLTAATGMDALTHAVEAYVSTIATPITDACALKAVELIAGFLRRAVKDGKDMEAR
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAFNAASAGERLGDVAIALGEKTRSAQAAIAA
IKRLAADVGIPAGLRELGVKEADIPTLADNALKDACGFTNPRKGSHEDVCAIFRAAM

Sequences:

>Translated_377_residues
MSTSAFFIPSLNLMGAGCLQQAVDAMRGHGFRRALIVTDQGLVKAGLAAKVADMLGKADIEPVIFDGVHPNPSCANVNAG
LALLKEKQCDVVVSLGGGSPHDCAKGIALVAVNGGKIQDYEGVDKSAKPQLPLVAINTTAGTASEMTRFCIITDESRHIK
MAIVDKHTTPILSVNDPETMAGMPASLTAATGMDALTHAVEAYVSTIATPITDACALKAVELIAGFLRRAVKDGKDMEAR
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAFNAASAGERLGDVAIALGEKTRSAQAAIAA
IKRLAADVGIPAGLRELGVKEADIPTLADNALKDACGFTNPRKGSHEDVCAIFRAAM
>Mature_376_residues
STSAFFIPSLNLMGAGCLQQAVDAMRGHGFRRALIVTDQGLVKAGLAAKVADMLGKADIEPVIFDGVHPNPSCANVNAGL
ALLKEKQCDVVVSLGGGSPHDCAKGIALVAVNGGKIQDYEGVDKSAKPQLPLVAINTTAGTASEMTRFCIITDESRHIKM
AIVDKHTTPILSVNDPETMAGMPASLTAATGMDALTHAVEAYVSTIATPITDACALKAVELIAGFLRRAVKDGKDMEARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAFNAASAGERLGDVAIALGEKTRSAQAAIAAI
KRLAADVGIPAGLRELGVKEADIPTLADNALKDACGFTNPRKGSHEDVCAIFRAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=27.9411764705882, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=68.668407310705, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=43.6997319034853, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI87082107, Length=371, Percent_Identity=36.9272237196765, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1787493, Length=396, Percent_Identity=33.8383838383838, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789386, Length=328, Percent_Identity=26.219512195122, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=411, Percent_Identity=26.0340632603406, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=377, Percent_Identity=55.7029177718833, Blast_Score=432, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24657991, Length=400, Percent_Identity=27.5, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39216; Mature: 39084

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSAFFIPSLNLMGAGCLQQAVDAMRGHGFRRALIVTDQGLVKAGLAAKVADMLGKADI
CCCCEEECCCCHHHCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
EPVIFDGVHPNPSCANVNAGLALLKEKQCDVVVSLGGGSPHDCAKGIALVAVNGGKIQDY
CCEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCHHHHHCCEEEEEECCCEEECC
EGVDKSAKPQLPLVAINTTAGTASEMTRFCIITDESRHIKMAIVDKHTTPILSVNDPETM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHH
AGMPASLTAATGMDALTHAVEAYVSTIATPITDACALKAVELIAGFLRRAVKDGKDMEAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAFNAASAGERL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
GDVAIALGEKTRSAQAAIAAIKRLAADVGIPAGLRELGVKEADIPTLADNALKDACGFTN
HHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCC
PRKGSHEDVCAIFRAAM
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STSAFFIPSLNLMGAGCLQQAVDAMRGHGFRRALIVTDQGLVKAGLAAKVADMLGKADI
CCCEEECCCCHHHCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
EPVIFDGVHPNPSCANVNAGLALLKEKQCDVVVSLGGGSPHDCAKGIALVAVNGGKIQDY
CCEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCHHHHHCCEEEEEECCCEEECC
EGVDKSAKPQLPLVAINTTAGTASEMTRFCIITDESRHIKMAIVDKHTTPILSVNDPETM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHH
AGMPASLTAATGMDALTHAVEAYVSTIATPITDACALKAVELIAGFLRRAVKDGKDMEAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAFNAASAGERL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
GDVAIALGEKTRSAQAAIAAIKRLAADVGIPAGLRELGVKEADIPTLADNALKDACGFTN
HHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCC
PRKGSHEDVCAIFRAAM
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]