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The map label for this gene is hbpA [H]

Identifier: 34498143

GI number: 34498143

Start: 2910009

End: 2911805

Strand: Reverse

Name: hbpA [H]

Synonym: CV_2688

Alternate gene names: 34498143

Gene position: 2911805-2910009 (Counterclockwise)

Preceding gene: 34498144

Following gene: 34498142

Centisome position: 61.29

GC content: 60.6

Gene sequence:

>1797_bases
ATGACGCACCTGAAATGGCTGCCCATGCTGGTACTGGGCGGCTCGCTCGCGCTGTCCGCTCACGCAGCCGACCCTAACAA
AGTGCTCCGGGTGTCGATCCCCGCGCCGGAAACCGGTTTCGACCCCGGCAAGGTCAACGATGTGTATTCGATCGGCGTGA
TCGAGAACATTTTCGAACCGCTGCTGAAATACGATTACCTGGCCCGGCCGCTGAAAATGAAGCCCAACACCGCGGCGGCG
ATGCCAGAAATATCCGCCGATGGCCGCGTTTACACGATACGGATCCGGCCCGGCATCTATTTCGCCGACGATCCGGTGTT
CAAGGGCAAGAAGCGCGAGCTGACTGCCGAAGACTACGCCTACTCCTTCAAGCGCTTCGCCGATCCTGTCGTCAACTCGC
CGGTTTCCAATATGATGACGGACTGGGTGCTGGGCCTGGCGGAAGCCGGCAAGCGCGCAAGCAAGACCGGCAAGTTCGAT
TATGCGGCGCCGATTCCCGGCATCCAGGTGCTGGATCGCTACACCTTGCGGCTGACGCTGACCAAGACCAACTTCATTTT
CCAGTACACGCTGGCGGCCAAGCAGTTCGGCGCCGTCGCTCGCGAGGCGATTGAGGCTTACAGCAAGGACACCATGTCCC
ATCCTGTCGGCACCGGTCCCTTCATGCTGAAAGAGTGGAAGCAGGGCAGCAAGATCGTGCTGGTGGCCAATCCGGGCTAC
CGCAAGGTGGTGTTCGACGGAGAGCCGGGCGCCGATCCTCAGGATCAGGCAATCGCCAGGGACATGGCCGGCAAGACCCT
GCCTGCGGTCGGTCGGGTGGAAATCCGTGTGATCGAGGAAGATCAGCCGCGCTGGCTGTCTTTTCTGAACAAGCAGCTGG
ATGTGGTGGCGGTGCCCAAGGCCGCGATGAAGACGGCGCTGCATGTGACGGACAACGATCCCTTCCAGACCTCGTTGAAT
CCGGTGCTGGCTAAGCGGGGCATCAGGTTGTCGCATGTGCTGAATCTGGACGTGACCTACGCCTATTTCAACATGCTGGA
CCCCGTTGTCGGTGGCTATGGCAAGGACAAGATCGCGCTGCGCCGCGCGATCGCGCTGGCATATCCGCTGAAGCAAGAGG
TGGTGCCTCTCATTTACGGCAACCAGGCGGTGCCGATGCAGGGCGCGGTGTCGACCGGCATGTCCGGCTCCAGCCCGGGC
TTCCGTGGCGAGGTCAAATATGATCCAGCGCTGGGCAACGCCTTGCTTGACCAGTTTGGCTACAAGATCGGGCCAGATGG
CTATCGCACGCTGCCTAACGGCAAGCCCTTGCTGATTACGCAGGCGACCCAGGCCTCGGCTTTGGACAAACAGTTCAACC
AGATCTGGCAGAAGACATTCGACAGTCTCAAGATCCGGGTGAATTTCAAGGTGGCCAAGTGGAACGAGAACCTGAAGAGC
GCCTATGGCCACAAGCTGCAGATGTGGAGTCTGGGCGGGACGGCTTCGATGCCGGACGGCGACGACACCATGATTGAGCT
GTGGACCGACAGCATCGCCAGCGGCAGCAATTTGTCCGCCTTCAGCCGGCCCAAGTTCGACCAACTGTTCGAGGCATCGC
GCCTGATGCCAAACGGGCCGGAACGCGAAGCCAAGTTCGAGCAGATGAACCGGGTGGTGGCGGCCTATCAGCCCTATGTC
TTGGGCGTGACCCGCTTCACCAACTCTTTGGCCCATGGCTATGTGCTCGGTTACAAGCCACACCCGATCTATACGATCGG
CGGCTTCTGGCGCTACGTCGACATCGCCCGGCATTGA

Upstream 100 bases:

>100_bases
ATTCATTCGCGCTTGTCATGGCTGCAGCAGTTGGCGATGGCGGGCGCAAAGAATAAAGCGGGCCGCGAAGGCCCCGCGCT
ACGAAGGAGAACAATTCAAG

Downstream 100 bases:

>100_bases
GTCCCATCTAGTTCGTTTCCGCCGGATGGCCGGACGGAGCAAGGAAAAAACATGTTCGCATTCATCATTCGCCGGCTCTG
GCAGATGATCCCCACCATGC

Product: binding protein component of ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MTHLKWLPMLVLGGSLALSAHAADPNKVLRVSIPAPETGFDPGKVNDVYSIGVIENIFEPLLKYDYLARPLKMKPNTAAA
MPEISADGRVYTIRIRPGIYFADDPVFKGKKRELTAEDYAYSFKRFADPVVNSPVSNMMTDWVLGLAEAGKRASKTGKFD
YAAPIPGIQVLDRYTLRLTLTKTNFIFQYTLAAKQFGAVAREAIEAYSKDTMSHPVGTGPFMLKEWKQGSKIVLVANPGY
RKVVFDGEPGADPQDQAIARDMAGKTLPAVGRVEIRVIEEDQPRWLSFLNKQLDVVAVPKAAMKTALHVTDNDPFQTSLN
PVLAKRGIRLSHVLNLDVTYAYFNMLDPVVGGYGKDKIALRRAIALAYPLKQEVVPLIYGNQAVPMQGAVSTGMSGSSPG
FRGEVKYDPALGNALLDQFGYKIGPDGYRTLPNGKPLLITQATQASALDKQFNQIWQKTFDSLKIRVNFKVAKWNENLKS
AYGHKLQMWSLGGTASMPDGDDTMIELWTDSIASGSNLSAFSRPKFDQLFEASRLMPNGPEREAKFEQMNRVVAAYQPYV
LGVTRFTNSLAHGYVLGYKPHPIYTIGGFWRYVDIARH

Sequences:

>Translated_598_residues
MTHLKWLPMLVLGGSLALSAHAADPNKVLRVSIPAPETGFDPGKVNDVYSIGVIENIFEPLLKYDYLARPLKMKPNTAAA
MPEISADGRVYTIRIRPGIYFADDPVFKGKKRELTAEDYAYSFKRFADPVVNSPVSNMMTDWVLGLAEAGKRASKTGKFD
YAAPIPGIQVLDRYTLRLTLTKTNFIFQYTLAAKQFGAVAREAIEAYSKDTMSHPVGTGPFMLKEWKQGSKIVLVANPGY
RKVVFDGEPGADPQDQAIARDMAGKTLPAVGRVEIRVIEEDQPRWLSFLNKQLDVVAVPKAAMKTALHVTDNDPFQTSLN
PVLAKRGIRLSHVLNLDVTYAYFNMLDPVVGGYGKDKIALRRAIALAYPLKQEVVPLIYGNQAVPMQGAVSTGMSGSSPG
FRGEVKYDPALGNALLDQFGYKIGPDGYRTLPNGKPLLITQATQASALDKQFNQIWQKTFDSLKIRVNFKVAKWNENLKS
AYGHKLQMWSLGGTASMPDGDDTMIELWTDSIASGSNLSAFSRPKFDQLFEASRLMPNGPEREAKFEQMNRVVAAYQPYV
LGVTRFTNSLAHGYVLGYKPHPIYTIGGFWRYVDIARH
>Mature_597_residues
THLKWLPMLVLGGSLALSAHAADPNKVLRVSIPAPETGFDPGKVNDVYSIGVIENIFEPLLKYDYLARPLKMKPNTAAAM
PEISADGRVYTIRIRPGIYFADDPVFKGKKRELTAEDYAYSFKRFADPVVNSPVSNMMTDWVLGLAEAGKRASKTGKFDY
AAPIPGIQVLDRYTLRLTLTKTNFIFQYTLAAKQFGAVAREAIEAYSKDTMSHPVGTGPFMLKEWKQGSKIVLVANPGYR
KVVFDGEPGADPQDQAIARDMAGKTLPAVGRVEIRVIEEDQPRWLSFLNKQLDVVAVPKAAMKTALHVTDNDPFQTSLNP
VLAKRGIRLSHVLNLDVTYAYFNMLDPVVGGYGKDKIALRRAIALAYPLKQEVVPLIYGNQAVPMQGAVSTGMSGSSPGF
RGEVKYDPALGNALLDQFGYKIGPDGYRTLPNGKPLLITQATQASALDKQFNQIWQKTFDSLKIRVNFKVAKWNENLKSA
YGHKLQMWSLGGTASMPDGDDTMIELWTDSIASGSNLSAFSRPKFDQLFEASRLMPNGPEREAKFEQMNRVVAAYQPYVL
GVTRFTNSLAHGYVLGYKPHPIYTIGGFWRYVDIARH

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=398, Percent_Identity=24.6231155778894, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 66233; Mature: 66102

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLKWLPMLVLGGSLALSAHAADPNKVLRVSIPAPETGFDPGKVNDVYSIGVIENIFEP
CCCCHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHH
LLKYDYLARPLKMKPNTAAAMPEISADGRVYTIRIRPGIYFADDPVFKGKKRELTAEDYA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCHHHHH
YSFKRFADPVVNSPVSNMMTDWVLGLAEAGKRASKTGKFDYAAPIPGIQVLDRYTLRLTL
HHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHCCCEEEEEEE
TKTNFIFQYTLAAKQFGAVAREAIEAYSKDTMSHPVGTGPFMLKEWKQGSKIVLVANPGY
EECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCC
RKVVFDGEPGADPQDQAIARDMAGKTLPAVGRVEIRVIEEDQPRWLSFLNKQLDVVAVPK
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCEEECCH
AAMKTALHVTDNDPFQTSLNPVLAKRGIRLSHVLNLDVTYAYFNMLDPVVGGYGKDKIAL
HHHHEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCCCHHHHH
RRAIALAYPLKQEVVPLIYGNQAVPMQGAVSTGMSGSSPGFRGEVKYDPALGNALLDQFG
HHHHHHHCCHHHCCEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHHCC
YKIGPDGYRTLPNGKPLLITQATQASALDKQFNQIWQKTFDSLKIRVNFKVAKWNENLKS
CEECCCCCEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHH
AYGHKLQMWSLGGTASMPDGDDTMIELWTDSIASGSNLSAFSRPKFDQLFEASRLMPNGP
HCCCEEEEEECCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EREAKFEQMNRVVAAYQPYVLGVTRFTNSLAHGYVLGYKPHPIYTIGGFWRYVDIARH
CHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCEEEECCCCCEEEECCCEEEEEECCC
>Mature Secondary Structure 
THLKWLPMLVLGGSLALSAHAADPNKVLRVSIPAPETGFDPGKVNDVYSIGVIENIFEP
CCCHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHH
LLKYDYLARPLKMKPNTAAAMPEISADGRVYTIRIRPGIYFADDPVFKGKKRELTAEDYA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCCCHHHHH
YSFKRFADPVVNSPVSNMMTDWVLGLAEAGKRASKTGKFDYAAPIPGIQVLDRYTLRLTL
HHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHCCCEEEEEEE
TKTNFIFQYTLAAKQFGAVAREAIEAYSKDTMSHPVGTGPFMLKEWKQGSKIVLVANPGY
EECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCC
RKVVFDGEPGADPQDQAIARDMAGKTLPAVGRVEIRVIEEDQPRWLSFLNKQLDVVAVPK
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCEEECCH
AAMKTALHVTDNDPFQTSLNPVLAKRGIRLSHVLNLDVTYAYFNMLDPVVGGYGKDKIAL
HHHHEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCCCHHHHH
RRAIALAYPLKQEVVPLIYGNQAVPMQGAVSTGMSGSSPGFRGEVKYDPALGNALLDQFG
HHHHHHHCCHHHCCEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHHCC
YKIGPDGYRTLPNGKPLLITQATQASALDKQFNQIWQKTFDSLKIRVNFKVAKWNENLKS
CEECCCCCEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHH
AYGHKLQMWSLGGTASMPDGDDTMIELWTDSIASGSNLSAFSRPKFDQLFEASRLMPNGP
HCCCEEEEEECCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EREAKFEQMNRVVAAYQPYVLGVTRFTNSLAHGYVLGYKPHPIYTIGGFWRYVDIARH
CHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCEEEECCCCCEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]