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The map label for this gene is cesD [H]

Identifier: 34498033

GI number: 34498033

Start: 2782366

End: 2782851

Strand: Reverse

Name: cesD [H]

Synonym: CV_2578

Alternate gene names: 34498033

Gene position: 2782851-2782366 (Counterclockwise)

Preceding gene: 34498034

Following gene: 34498032

Centisome position: 58.57

GC content: 61.11

Gene sequence:

>486_bases
ATGACTGATATCCATCATCAGCCTGAGCAGACAGACGACGAGTTGTACCGGCATTTCTTCTCGCGCGGCGGCTCGTTGCG
CTTGCTGGCCGACATTCAGGGCGAGGACCTGGAGTCGCTGTACGGCTATGCCAAGCAGCTGTTCGATGGCGGCGAAATCG
CTGCCGCCCGAAATGTCTACCAGTTGCTGAGCACGCTGGACCACTGGAATTTCGACTACCTGCTGGCGCTGGGCCTGTGC
CATCAGCGGCTCGGCGCGCACAACGAGGCCGTGGTCTGCTTCGGCCGCGCCGGCCTGATCAAGGTGGACGACCCGCGCGC
CGCGTTCTACGCCGGCATCAGCTATCGGCTGGACGGGAATGCGGAGTATGCGAGCAAGGCTTTCAAGGCGGCCATCAACT
GGTGCGGCGAACAAATCGATTATCAGGCAATCAAGGCCAGCGCCGTAGACATGCTGGCTCTGCAACAGGAGGAAGTACCA
TGCTGA

Upstream 100 bases:

>100_bases
AATCGACCAAGTCTATCGCCCAAGCTATCCGTTAAGCCACGACATGTTGCCGGGTGGTCTTGTCTCCGGCCGGCGCGTGT
CAGTACAAGGAGTTTATTTT

Downstream 100 bases:

>100_bases
TCGCACTCGATCGTTTCATGCCTGGCGCCGGCTTGCCGGCTGATTGGGCGGAGAAGGAAGAAGGAAAAAGCGGCGCCGCC
CGCAAAGTCGGCGATGCCGT

Product: type III secretion system CesD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTDIHHQPEQTDDELYRHFFSRGGSLRLLADIQGEDLESLYGYAKQLFDGGEIAAARNVYQLLSTLDHWNFDYLLALGLC
HQRLGAHNEAVVCFGRAGLIKVDDPRAAFYAGISYRLDGNAEYASKAFKAAINWCGEQIDYQAIKASAVDMLALQQEEVP
C

Sequences:

>Translated_161_residues
MTDIHHQPEQTDDELYRHFFSRGGSLRLLADIQGEDLESLYGYAKQLFDGGEIAAARNVYQLLSTLDHWNFDYLLALGLC
HQRLGAHNEAVVCFGRAGLIKVDDPRAAFYAGISYRLDGNAEYASKAFKAAINWCGEQIDYQAIKASAVDMLALQQEEVP
C
>Mature_160_residues
TDIHHQPEQTDDELYRHFFSRGGSLRLLADIQGEDLESLYGYAKQLFDGGEIAAARNVYQLLSTLDHWNFDYLLALGLCH
QRLGAHNEAVVCFGRAGLIKVDDPRAAFYAGISYRLDGNAEYASKAFKAAINWCGEQIDYQAIKASAVDMLALQQEEVPC

Specific function: Mediates the negative regulation of the lcrGVH operon by ATP or calcium. Acts as a modulator of the yop operon expression [H]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lcrH/sycD chaperone family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005415
- InterPro:   IPR016379
- InterPro:   IPR011716
- InterPro:   IPR013026
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 18005; Mature: 17874

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIHHQPEQTDDELYRHFFSRGGSLRLLADIQGEDLESLYGYAKQLFDGGEIAAARNVY
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHH
QLLSTLDHWNFDYLLALGLCHQRLGAHNEAVVCFGRAGLIKVDDPRAAFYAGISYRLDGN
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCHHHHCCEEEEECCC
AEYASKAFKAAINWCGEQIDYQAIKASAVDMLALQQEEVPC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDIHHQPEQTDDELYRHFFSRGGSLRLLADIQGEDLESLYGYAKQLFDGGEIAAARNVY
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHH
QLLSTLDHWNFDYLLALGLCHQRLGAHNEAVVCFGRAGLIKVDDPRAAFYAGISYRLDGN
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCHHHHCCEEEEECCC
AEYASKAFKAAINWCGEQIDYQAIKASAVDMLALQQEEVPC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477361; 9746557; 9748454; 11586360 [H]