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The map label for this gene is sseC [H]

Identifier: 34498032

GI number: 34498032

Start: 2780861

End: 2782348

Strand: Reverse

Name: sseC [H]

Synonym: CV_2577

Alternate gene names: 34498032

Gene position: 2782348-2780861 (Counterclockwise)

Preceding gene: 34498033

Following gene: 34498031

Centisome position: 58.56

GC content: 57.06

Gene sequence:

>1488_bases
ATGCCTGGCGCCGGCTTGCCGGCTGATTGGGCGGAGAAGGAAGAAGGAAAAAGCGGCGCCGCCCGCAAAGTCGGCGATGC
CGTCAAGATGGTCTCCAGACCGTTGGCGGAGGTGCAATCGCAGCAACTGGGGCAGTTGGCTTCGCCGCGCGCCGCCAAGG
AGCCGGTATCCCGGCAACAGGCAGCCGATGCGCTGGGCCGGATCATGGGAACTATCGATCAAGCCTCCGGCAGCGATGGC
GCGGCCAAGGTGCCGGCATTCAGCTTGTCGGAGATCGAAAAGATTCCGATGGACTCGATGATCATGGCTTCCACGCTGAT
GACCTCGCAAATGCTGGGCGATACCGCAGCAGTCAAGAGCAAGGCTCTCGACATCATGAGTACGAAGCAGGAAGCGCTGC
GCAAGAAGGAAGTGGAGAACATTCGGGAACAGATGAACAAGGCCATCGAGCAGCAGGACAAGGCCAAGAAGGCTGGCATT
CTCAGCGTGGTTTTCGACTGGGTGGTCGCTGCGGTGGAGGTGGTGACTGGCGTCGCCAAAATGATAGGCGGTGTGATGAC
CGGCAATGTGATGCAGGCTGCCGGCGGTGCGATGGACCTCGTTGCTGGCATGGCGGGTCTGGTCAAGGCTATGGCTAATA
CGATGGCGCTTATTGACCCGGAGAATGCCGAAAAATACCAAAAGGTAGCGGACATTGCTGGAAAAATTCAATTGTCGTTT
GAAATCGCCGGAGCGGTGGTGGACGTTACCAGTGCGGCGCGCAATCTGTTGGTGACCAAGATGATTCCGAAAGTCGCCGG
CAAGGTACTGAAAGAAGGCGCGGAGCAAATGGTCAGTACAGCCATCAAGAAAGGCACGGCAGGCGCAGCCAAGAATGCGG
CAAACGCAGTTGGCAAGCAAGTGGCGGATCAAGTCGCGACACAAGTTGCACAAGCGTTGGGCAAGGCCGCTGTCGATGCC
GCCAAAGCCACCACCAAGAAGACAGTTGAGAAGTTCGCCCAGAAGTTTACCAACCAGATGCTGGAAAGGTTCACCCACGA
AGCGATAGAAAAGATGGTGAGCAAGTCGGTGGAGAAAGTCATCAAGAAGGCTGTCAAGGAAGGTGTGGAACTGACTGCCC
AGGAGGTCACCAAGCGAGTCGTGAATCAGGTATTCGCGGACGTGGTCAAGGCTACGATCAAAGCGACGCTGAAGGCACCG
GCGCTTGTCGTGTCCAGCACGGTCCGCGGAGTGGCGGCAGGTGCAAAGGAGATCATGGTCGGTGAGATCGAGAAACAGCG
AGCCAAACTGCAAAAGGAAATCGATTTGTTGATTCTGGATCAGCAATGGCTGCAGAGCTTCTTCGAGTTCTATGAGCAGG
AAAAGAAGGAAGTCATCAAGAAGACGCGCGAACTGCTGGACAGCAAGAGCCAGGTGATCGATGACGGCCTCCAGGCGATG
AGCCAGGCAGCTTCCACCCAGGCGCAGATCGCGTCTTCCATGGTGTAG

Upstream 100 bases:

>100_bases
GCGGCGAACAAATCGATTATCAGGCAATCAAGGCCAGCGCCGTAGACATGCTGGCTCTGCAACAGGAGGAAGTACCATGC
TGATCGCACTCGATCGTTTC

Downstream 100 bases:

>100_bases
AGGGGAGAGAGATGACGGATTTTTCGGTGGCTAGATTTAGCCAGAGTACAGGTGCGAATGGCGTCCCCGGGGAGTATTCC
GTCAACTCGAAAAAAACCGG

Product: secretion system effector

Products: NA

Alternate protein names: Secretion system effector C [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MPGAGLPADWAEKEEGKSGAARKVGDAVKMVSRPLAEVQSQQLGQLASPRAAKEPVSRQQAADALGRIMGTIDQASGSDG
AAKVPAFSLSEIEKIPMDSMIMASTLMTSQMLGDTAAVKSKALDIMSTKQEALRKKEVENIREQMNKAIEQQDKAKKAGI
LSVVFDWVVAAVEVVTGVAKMIGGVMTGNVMQAAGGAMDLVAGMAGLVKAMANTMALIDPENAEKYQKVADIAGKIQLSF
EIAGAVVDVTSAARNLLVTKMIPKVAGKVLKEGAEQMVSTAIKKGTAGAAKNAANAVGKQVADQVATQVAQALGKAAVDA
AKATTKKTVEKFAQKFTNQMLERFTHEAIEKMVSKSVEKVIKKAVKEGVELTAQEVTKRVVNQVFADVVKATIKATLKAP
ALVVSSTVRGVAAGAKEIMVGEIEKQRAKLQKEIDLLILDQQWLQSFFEFYEQEKKEVIKKTRELLDSKSQVIDDGLQAM
SQAASTQAQIASSMV

Sequences:

>Translated_495_residues
MPGAGLPADWAEKEEGKSGAARKVGDAVKMVSRPLAEVQSQQLGQLASPRAAKEPVSRQQAADALGRIMGTIDQASGSDG
AAKVPAFSLSEIEKIPMDSMIMASTLMTSQMLGDTAAVKSKALDIMSTKQEALRKKEVENIREQMNKAIEQQDKAKKAGI
LSVVFDWVVAAVEVVTGVAKMIGGVMTGNVMQAAGGAMDLVAGMAGLVKAMANTMALIDPENAEKYQKVADIAGKIQLSF
EIAGAVVDVTSAARNLLVTKMIPKVAGKVLKEGAEQMVSTAIKKGTAGAAKNAANAVGKQVADQVATQVAQALGKAAVDA
AKATTKKTVEKFAQKFTNQMLERFTHEAIEKMVSKSVEKVIKKAVKEGVELTAQEVTKRVVNQVFADVVKATIKATLKAP
ALVVSSTVRGVAAGAKEIMVGEIEKQRAKLQKEIDLLILDQQWLQSFFEFYEQEKKEVIKKTRELLDSKSQVIDDGLQAM
SQAASTQAQIASSMV
>Mature_494_residues
PGAGLPADWAEKEEGKSGAARKVGDAVKMVSRPLAEVQSQQLGQLASPRAAKEPVSRQQAADALGRIMGTIDQASGSDGA
AKVPAFSLSEIEKIPMDSMIMASTLMTSQMLGDTAAVKSKALDIMSTKQEALRKKEVENIREQMNKAIEQQDKAKKAGIL
SVVFDWVVAAVEVVTGVAKMIGGVMTGNVMQAAGGAMDLVAGMAGLVKAMANTMALIDPENAEKYQKVADIAGKIQLSFE
IAGAVVDVTSAARNLLVTKMIPKVAGKVLKEGAEQMVSTAIKKGTAGAAKNAANAVGKQVADQVATQVAQALGKAAVDAA
KATTKKTVEKFAQKFTNQMLERFTHEAIEKMVSKSVEKVIKKAVKEGVELTAQEVTKRVVNQVFADVVKATIKATLKAPA
LVVSSTVRGVAAGAKEIMVGEIEKQRAKLQKEIDLLILDQQWLQSFFEFYEQEKKEVIKKTRELLDSKSQVIDDGLQAMS
QAASTQAQIASSMV

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells [H]

COG id: COG5613

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006972 [H]

Pfam domain/function: PF04888 SseC [H]

EC number: NA

Molecular weight: Translated: 52516; Mature: 52384

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGAGLPADWAEKEEGKSGAARKVGDAVKMVSRPLAEVQSQQLGQLASPRAAKEPVSRQQ
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHHH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HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609 [H]