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The map label for this gene is argC [H]

Identifier: 33862981

GI number: 33862981

Start: 765346

End: 766461

Strand: Direct

Name: argC [H]

Synonym: PMT0709

Alternate gene names: 33862981

Gene position: 765346-766461 (Clockwise)

Preceding gene: 33862979

Following gene: 33862983

Centisome position: 31.75

GC content: 50.81

Gene sequence:

>1116_bases
ATGAAGGCAATGGAAAGTCCCCCTCGCTCTCCAGCCTCTGACATTTCTCAGGTTCGAGGCAGCCGAGTAGCGGTTATCGG
CGCTACGGGCTACGGCGGTCTTCAAACCATCAGATTGCTTGAGGACCATCCCCACCTCCATGTGACCTACCTGGGCGGCG
AACGAAGTGCCGGCAGGCGATGGAGTGAGCTTTGCCCTTTTTTACCCATCCTTGATGATCCTGAAGTTCAATCTCCCGAT
CCTGACAAGATCGCTGAATTCGCCGATTACGCAGTCCTCAGCCTTCCCAATGGACTTGCCTGCCAATTAGCACCGCAACT
GCTGAAACGCAATGTTCGGGTTGTAGACCTCTCTGCTGACTTTCGCTATCGCTCACTGGAACAATGGAAACAAGTTTATG
TCCATGAAGCTCAAAACCTCAATCGAGATGATGTTCAGCTTTGTAGAGAGGCTGTTTATGGGTTACCTGAATGGAAGGGA
CCTGAAATTGCAGTTGCAAATCTTGTCGCTGCACCGGGATGCTTCCCAACCGCAAGTTTGTTGCCCTTGCTGCCTTTTCT
AAAGCAGGGATTGATCGAAAACGATGGTTTGATTATCGATGCAAAAACTGGCACCTCTGGTGGAGGGAGGGTGGCCAAAG
AACAATTTCTTCTGGCAGAGGCCTCGGAGTCGATCATGCCTTATGGCGTGGTAGGACATCGACATACATCAGAAATCGAA
CAACTTGCTAGTGAGGTTGCCGGACAGCCGATTGAGCTTCAGTTCACACCCCATCTCGTACCGATGGTGCGTGGACTGCT
AGCGACGGTTTATGGACGTTTGAGAGATCCTGGATTGACCGCTGAGGATTGCACAACTGTGCTTAAAGCGGTCTATCGAC
ATCATCCCTGCATCGATGTTCTTCCTGTGGGAACGTATCCAGCGACTAAGTGGGTGAAGTACTCCAACAAAGCTGTTCTT
TCTGTTCAGGTCGACAACCGCAACAGCCGGCTTGTCTTGATGAGCGCTGTTGACAACCTGATTAAAGGCCAAGCTGGTCA
AGGGGTTCAATGTCTAAACCTGATGGCTGGATTACCACCAACCACAGGGATGTCTTTACTGACCTTCTACCCTTAA

Upstream 100 bases:

>100_bases
GGATCTCGACCGATTCAGCGGGTATAGGAGATGTCCTCAGGGCCTTAGGGATGAACGTACTGGGTTCATTATCGACACCA
GTACGATCAGCCGGCGTCCG

Downstream 100 bases:

>100_bases
TTTTGAGCTGCGTTTCTCCAATTCTGGCCTGCAAGAGCAACAGATAATGGAAGCAGTTGATGCTCCATGCGCTGGATCCT
TTTGCTGAGGCTCTGATGGT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKAMESPPRSPASDISQVRGSRVAVIGATGYGGLQTIRLLEDHPHLHVTYLGGERSAGRRWSELCPFLPILDDPEVQSPD
PDKIAEFADYAVLSLPNGLACQLAPQLLKRNVRVVDLSADFRYRSLEQWKQVYVHEAQNLNRDDVQLCREAVYGLPEWKG
PEIAVANLVAAPGCFPTASLLPLLPFLKQGLIENDGLIIDAKTGTSGGGRVAKEQFLLAEASESIMPYGVVGHRHTSEIE
QLASEVAGQPIELQFTPHLVPMVRGLLATVYGRLRDPGLTAEDCTTVLKAVYRHHPCIDVLPVGTYPATKWVKYSNKAVL
SVQVDNRNSRLVLMSAVDNLIKGQAGQGVQCLNLMAGLPPTTGMSLLTFYP

Sequences:

>Translated_371_residues
MKAMESPPRSPASDISQVRGSRVAVIGATGYGGLQTIRLLEDHPHLHVTYLGGERSAGRRWSELCPFLPILDDPEVQSPD
PDKIAEFADYAVLSLPNGLACQLAPQLLKRNVRVVDLSADFRYRSLEQWKQVYVHEAQNLNRDDVQLCREAVYGLPEWKG
PEIAVANLVAAPGCFPTASLLPLLPFLKQGLIENDGLIIDAKTGTSGGGRVAKEQFLLAEASESIMPYGVVGHRHTSEIE
QLASEVAGQPIELQFTPHLVPMVRGLLATVYGRLRDPGLTAEDCTTVLKAVYRHHPCIDVLPVGTYPATKWVKYSNKAVL
SVQVDNRNSRLVLMSAVDNLIKGQAGQGVQCLNLMAGLPPTTGMSLLTFYP
>Mature_371_residues
MKAMESPPRSPASDISQVRGSRVAVIGATGYGGLQTIRLLEDHPHLHVTYLGGERSAGRRWSELCPFLPILDDPEVQSPD
PDKIAEFADYAVLSLPNGLACQLAPQLLKRNVRVVDLSADFRYRSLEQWKQVYVHEAQNLNRDDVQLCREAVYGLPEWKG
PEIAVANLVAAPGCFPTASLLPLLPFLKQGLIENDGLIIDAKTGTSGGGRVAKEQFLLAEASESIMPYGVVGHRHTSEIE
QLASEVAGQPIELQFTPHLVPMVRGLLATVYGRLRDPGLTAEDCTTVLKAVYRHHPCIDVLPVGTYPATKWVKYSNKAVL
SVQVDNRNSRLVLMSAVDNLIKGQAGQGVQCLNLMAGLPPTTGMSLLTFYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320913, Length=350, Percent_Identity=25.4285714285714, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 40449; Mature: 40449

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMESPPRSPASDISQVRGSRVAVIGATGYGGLQTIRLLEDHPHLHVTYLGGERSAGRR
CCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCHHEEHEECCCCCEEEEEECCCCCCCCC
WSELCPFLPILDDPEVQSPDPDKIAEFADYAVLSLPNGLACQLAPQLLKRNVRVVDLSAD
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCEEEEECCC
FRYRSLEQWKQVYVHEAQNLNRDDVQLCREAVYGLPEWKGPEIAVANLVAAPGCFPTASL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCCHHHH
LPLLPFLKQGLIENDGLIIDAKTGTSGGGRVAKEQFLLAEASESIMPYGVVGHRHTSEIE
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QLASEVAGQPIELQFTPHLVPMVRGLLATVYGRLRDPGLTAEDCTTVLKAVYRHHPCIDV
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
LPVGTYPATKWVKYSNKAVLSVQVDNRNSRLVLMSAVDNLIKGQAGQGVQCLNLMAGLPP
EECCCCCCHHHEEECCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCC
TTGMSLLTFYP
CCCCCEEEECC
>Mature Secondary Structure
MKAMESPPRSPASDISQVRGSRVAVIGATGYGGLQTIRLLEDHPHLHVTYLGGERSAGRR
CCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCHHEEHEECCCCCEEEEEECCCCCCCCC
WSELCPFLPILDDPEVQSPDPDKIAEFADYAVLSLPNGLACQLAPQLLKRNVRVVDLSAD
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCEEEEECCC
FRYRSLEQWKQVYVHEAQNLNRDDVQLCREAVYGLPEWKGPEIAVANLVAAPGCFPTASL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCCHHHH
LPLLPFLKQGLIENDGLIIDAKTGTSGGGRVAKEQFLLAEASESIMPYGVVGHRHTSEIE
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QLASEVAGQPIELQFTPHLVPMVRGLLATVYGRLRDPGLTAEDCTTVLKAVYRHHPCIDV
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
LPVGTYPATKWVKYSNKAVLSVQVDNRNSRLVLMSAVDNLIKGQAGQGVQCLNLMAGLPP
EECCCCCCHHHEEECCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCC
TTGMSLLTFYP
CCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]