| Definition | Prochlorococcus marinus str. MIT 9313 chromosome, complete genome. |
|---|---|
| Accession | NC_005071 |
| Length | 2,410,873 |
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The map label for this gene is rot [H]
Identifier: 33862979
GI number: 33862979
Start: 763133
End: 763561
Strand: Direct
Name: rot [H]
Synonym: PMT0707
Alternate gene names: 33862979
Gene position: 763133-763561 (Clockwise)
Preceding gene: 33862978
Following gene: 33862981
Centisome position: 31.65
GC content: 46.85
Gene sequence:
>429_bases ATGGACACTGATGCTGGTTTGATTGAGTTGGACCTCTTTGATGATGATGCTCCCAACACGGTTGCCAATTTCACAAAGCT GGTTAAGGAGGGTTTTTATGACGGCCTGTCTTTCCATCGTGTGATCGATGGTTTCATGGCTCAAGGTGGCTGCCCAAATA CTCGTGAGGGGGCAAAGGGCATGCCTGGAACCGGTGGGCCTGGCTATACGATTAATTGTGAAATAAATAGCAAAAAGCAT CTCGCCGGTTCTCTTTCTATGGCTCATGCAGGAAAGAACACTGGTGGAAGTCAATTCTTTCTTGTCCATGATGCTCAGCC TCATCTCGATGGTGTGCATACCGTTTTCGGTCAGGCTGCCAACATGGATGTGGTCTTAGCCTTAAAGAACGGCTCTAGGA TCAATAAAGTAACCATTCAAGAGAATTGA
Upstream 100 bases:
>100_bases ACTATTACTTTGATTCAATTAATATTTCTAGAGATGTCGCGAAAGTTGGCTTAACTGACTAGACTATTTTTTTGAGCATC CAACTGTGACCAAGGCCCTG
Downstream 100 bases:
>100_bases AAATATACAGTTGGTCTCTTTCACGACCAAAGGATCAGATTGGGAAAGCTCGTGGCATCCCAATCTTTTAGTGGTGAAAA ATCATCTTTAAATAGTGTTG
Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 142; Mature: 142
Protein sequence:
>142_residues MDTDAGLIELDLFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANMDVVLALKNGSRINKVTIQEN
Sequences:
>Translated_142_residues MDTDAGLIELDLFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANMDVVLALKNGSRINKVTIQEN >Mature_142_residues MDTDAGLIELDLFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKGMPGTGGPGYTINCEINSKKH LAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAANMDVVLALKNGSRINKVTIQEN
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI24308049, Length=131, Percent_Identity=41.2213740458015, Blast_Score=86, Evalue=1e-17, Organism=Homo sapiens, GI7706339, Length=121, Percent_Identity=38.8429752066116, Blast_Score=86, Evalue=1e-17, Organism=Homo sapiens, GI19557636, Length=141, Percent_Identity=35.4609929078014, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI10863927, Length=149, Percent_Identity=41.6107382550336, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI64276486, Length=144, Percent_Identity=34.7222222222222, Blast_Score=78, Evalue=3e-15, Organism=Homo sapiens, GI6631100, Length=123, Percent_Identity=41.4634146341463, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI4826932, Length=124, Percent_Identity=41.1290322580645, Blast_Score=76, Evalue=1e-14, Organism=Homo sapiens, GI256017253, Length=146, Percent_Identity=39.041095890411, Blast_Score=74, Evalue=3e-14, Organism=Homo sapiens, GI221139811, Length=146, Percent_Identity=39.041095890411, Blast_Score=74, Evalue=3e-14, Organism=Homo sapiens, GI256017251, Length=146, Percent_Identity=39.041095890411, Blast_Score=74, Evalue=3e-14, Organism=Homo sapiens, GI4505991, Length=133, Percent_Identity=41.3533834586466, Blast_Score=74, Evalue=4e-14, Organism=Homo sapiens, GI42560244, Length=138, Percent_Identity=36.9565217391304, Blast_Score=72, Evalue=1e-13, Organism=Homo sapiens, GI5031987, Length=158, Percent_Identity=38.6075949367089, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI209417936, Length=146, Percent_Identity=38.3561643835616, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI30102944, Length=146, Percent_Identity=38.3561643835616, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI219842199, Length=146, Percent_Identity=38.3561643835616, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310129267, Length=143, Percent_Identity=39.1608391608392, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310120620, Length=143, Percent_Identity=39.1608391608392, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310110104, Length=146, Percent_Identity=38.3561643835616, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI4758950, Length=133, Percent_Identity=39.0977443609023, Blast_Score=71, Evalue=3e-13, Organism=Homo sapiens, GI303305009, Length=150, Percent_Identity=40, Blast_Score=71, Evalue=3e-13, Organism=Homo sapiens, GI178057341, Length=152, Percent_Identity=38.1578947368421, Blast_Score=71, Evalue=3e-13, Organism=Homo sapiens, GI5174637, Length=148, Percent_Identity=40.5405405405405, Blast_Score=71, Evalue=3e-13, Organism=Homo sapiens, GI45439316, Length=134, Percent_Identity=41.044776119403, Blast_Score=70, Evalue=6e-13, Organism=Homo sapiens, GI150418007, Length=146, Percent_Identity=35.6164383561644, Blast_Score=67, Evalue=6e-12, Organism=Homo sapiens, GI22547212, Length=131, Percent_Identity=34.3511450381679, Blast_Score=66, Evalue=8e-12, Organism=Homo sapiens, GI7657473, Length=131, Percent_Identity=34.3511450381679, Blast_Score=66, Evalue=8e-12, Organism=Homo sapiens, GI22547215, Length=131, Percent_Identity=34.3511450381679, Blast_Score=66, Evalue=8e-12, Organism=Homo sapiens, GI169164185, Length=143, Percent_Identity=37.0629370629371, Blast_Score=66, Evalue=1e-11, Organism=Homo sapiens, GI169163623, Length=143, Percent_Identity=37.0629370629371, Blast_Score=66, Evalue=1e-11, Organism=Homo sapiens, GI169163387, Length=143, Percent_Identity=37.0629370629371, Blast_Score=65, Evalue=1e-11, Organism=Homo sapiens, GI5454154, Length=135, Percent_Identity=34.8148148148148, Blast_Score=63, Evalue=8e-11, Organism=Homo sapiens, GI310132444, Length=146, Percent_Identity=36.3013698630137, Blast_Score=63, Evalue=1e-10, Organism=Homo sapiens, GI310113152, Length=146, Percent_Identity=36.3013698630137, Blast_Score=63, Evalue=1e-10, Organism=Escherichia coli, GI1789763, Length=139, Percent_Identity=35.9712230215827, Blast_Score=65, Evalue=1e-12, Organism=Escherichia coli, GI1786736, Length=102, Percent_Identity=39.2156862745098, Blast_Score=63, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17539496, Length=133, Percent_Identity=45.8646616541353, Blast_Score=97, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17506311, Length=146, Percent_Identity=40.4109589041096, Blast_Score=80, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17506307, Length=134, Percent_Identity=41.044776119403, Blast_Score=76, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71980594, Length=122, Percent_Identity=37.7049180327869, Blast_Score=76, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71980590, Length=122, Percent_Identity=37.7049180327869, Blast_Score=76, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71997782, Length=122, Percent_Identity=37.7049180327869, Blast_Score=76, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17565860, Length=145, Percent_Identity=39.3103448275862, Blast_Score=73, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17559074, Length=148, Percent_Identity=40.5405405405405, Blast_Score=73, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17551284, Length=136, Percent_Identity=38.2352941176471, Blast_Score=73, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17551282, Length=136, Percent_Identity=38.2352941176471, Blast_Score=73, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17532641, Length=123, Percent_Identity=36.5853658536585, Blast_Score=72, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17552780, Length=130, Percent_Identity=40, Blast_Score=72, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17552782, Length=140, Percent_Identity=39.2857142857143, Blast_Score=70, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17539498, Length=133, Percent_Identity=39.0977443609023, Blast_Score=69, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17566266, Length=144, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17552784, Length=124, Percent_Identity=35.4838709677419, Blast_Score=65, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17532643, Length=135, Percent_Identity=37.037037037037, Blast_Score=63, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6323562, Length=133, Percent_Identity=42.8571428571429, Blast_Score=84, Evalue=6e-18, Organism=Saccharomyces cerevisiae, GI6320510, Length=135, Percent_Identity=40.7407407407407, Blast_Score=77, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6320359, Length=131, Percent_Identity=41.2213740458015, Blast_Score=73, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6321848, Length=138, Percent_Identity=40.5797101449275, Blast_Score=72, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6323246, Length=131, Percent_Identity=38.9312977099237, Blast_Score=63, Evalue=1e-11, Organism=Drosophila melanogaster, GI19922376, Length=137, Percent_Identity=37.2262773722628, Blast_Score=87, Evalue=4e-18, Organism=Drosophila melanogaster, GI17986117, Length=133, Percent_Identity=39.8496240601504, Blast_Score=84, Evalue=3e-17, Organism=Drosophila melanogaster, GI24650807, Length=125, Percent_Identity=43.2, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI20130249, Length=133, Percent_Identity=42.1052631578947, Blast_Score=81, Evalue=3e-16, Organism=Drosophila melanogaster, GI19922912, Length=132, Percent_Identity=39.3939393939394, Blast_Score=78, Evalue=1e-15, Organism=Drosophila melanogaster, GI21357249, Length=123, Percent_Identity=34.9593495934959, Blast_Score=74, Evalue=3e-14, Organism=Drosophila melanogaster, GI24664125, Length=146, Percent_Identity=39.041095890411, Blast_Score=73, Evalue=5e-14, Organism=Drosophila melanogaster, GI21357783, Length=146, Percent_Identity=39.041095890411, Blast_Score=73, Evalue=5e-14, Organism=Drosophila melanogaster, GI17647301, Length=147, Percent_Identity=38.7755102040816, Blast_Score=72, Evalue=9e-14, Organism=Drosophila melanogaster, GI45549139, Length=130, Percent_Identity=40.7692307692308, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI24652460, Length=119, Percent_Identity=36.1344537815126, Blast_Score=71, Evalue=3e-13, Organism=Drosophila melanogaster, GI17136360, Length=131, Percent_Identity=34.3511450381679, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24586038, Length=136, Percent_Identity=37.5, Blast_Score=64, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 15065; Mature: 15065
Theoretical pI: Translated: 5.89; Mature: 5.89
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDTDAGLIELDLFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKG CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC MPGTGGPGYTINCEINSKKHLAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAA CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCC NMDVVLALKNGSRINKVTIQEN CCEEEEEECCCCEEEEEEEECC >Mature Secondary Structure MDTDAGLIELDLFDDDAPNTVANFTKLVKEGFYDGLSFHRVIDGFMAQGGCPNTREGAKG CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC MPGTGGPGYTINCEINSKKHLAGSLSMAHAGKNTGGSQFFLVHDAQPHLDGVHTVFGQAA CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCC NMDVVLALKNGSRINKVTIQEN CCEEEEEECCCCEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA