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The map label for this gene is murQ [H]

Identifier: 33862978

GI number: 33862978

Start: 761920

End: 762870

Strand: Direct

Name: murQ [H]

Synonym: PMT0706

Alternate gene names: 33862978

Gene position: 761920-762870 (Clockwise)

Preceding gene: 33862977

Following gene: 33862979

Centisome position: 31.6

GC content: 47.74

Gene sequence:

>951_bases
ATGACCAATGTATTTGCAGATCTCAATTTGCATCCTTCAGATAATCGAGGGCATCTGTTGACTGAAAAGGTCAATCCCAA
AAGTGAATGTTTGGATCAACTAACCACAGAGTCCTTAGTGACACTTTTCTGCGAAGAGGACCGAGAGCCACAGCGCGCCG
TCGCAGCGGCTATACCCGAACTTATTCAGGCAGTTGAAGCGATTACGGACCGGCTTCGAAGCGGAGGTCGCCTTTTTTAT
TTGGGTGCTGGCACCTCCGGACGACTAGGTGTTCTTGACGCCGCAGAGTGCCCACCAACCTTTTGCAGCGATCCTGATCT
TGTTCAGGGTGTTCTTGCTGGTGGGAGCGCAGCTTTGCTGAAAAGTTCCGAGGGACTTGAAGACATTGAACAGTTAGGAA
AAAAGGATCTTGAGGAGCGTGACTTTAGCCCTGCTGATTGTCTTGTCGGTATTGCGGCCGGGGGAACGACTCCTTATGTC
AAAGGAGGACTTGCATACGCAAAGGAAATCAATGCTTTGGCGATTGCAATTTCATGTGTGCCTATAGAACAAGCTGAGTT
GCCATGCAGTATCGATATTCGTCTTTTGACTGGCCCTGAATTACTTACAGGTTCCACGCGCTTGAAGGCCGGCACCGCAA
CAAAGATGGCTCTAAATATTCTTTCAACATGTGCGATGGTTCGTCTTGGCAAAGTCTTTGGTAATCGAATGGTTGATGTT
GCTGCTACCAACATCAAGCTGATGGATCGTGCCCTGCGAATCCTGCATGATTTAGCTGATGTTGATCGAGTTCGTGGAAC
TGAGTTGCTTCAAGCAAGCGATGGATCTGTAAAAGTGGCTCTGCTGATGCATACTTGCGGTTTAGACGCTGAGACTGCCC
AGAAACTACTGATAGAGCATAATAATCAATTGCGAACAGCTTTGGCGAGGTGTAAAAATTGTATTGCTTGA

Upstream 100 bases:

>100_bases
ATGCGGATCATTCCGTTGCAGCCAGCAATGGATTGGATCAGCAAGTTGAATCAACAGATCTTGAAGAGATTCGTAAGCGG
CTTGAAGGGTTGATTTGACA

Downstream 100 bases:

>100_bases
TTTTAATTGTGCCTTTGCAAAAAGCAAGATAGTAAAATCATTCTACTCGGTAGGTACACGATAGCAATAACAGATTCTAA
ACGATTTGAATATCTTGTAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTNVFADLNLHPSDNRGHLLTEKVNPKSECLDQLTTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFY
LGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSAALLKSSEGLEDIEQLGKKDLEERDFSPADCLVGIAAGGTTPYV
KGGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
AATNIKLMDRALRILHDLADVDRVRGTELLQASDGSVKVALLMHTCGLDAETAQKLLIEHNNQLRTALARCKNCIA

Sequences:

>Translated_316_residues
MTNVFADLNLHPSDNRGHLLTEKVNPKSECLDQLTTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFY
LGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSAALLKSSEGLEDIEQLGKKDLEERDFSPADCLVGIAAGGTTPYV
KGGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
AATNIKLMDRALRILHDLADVDRVRGTELLQASDGSVKVALLMHTCGLDAETAQKLLIEHNNQLRTALARCKNCIA
>Mature_315_residues
TNVFADLNLHPSDNRGHLLTEKVNPKSECLDQLTTESLVTLFCEEDREPQRAVAAAIPELIQAVEAITDRLRSGGRLFYL
GAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSAALLKSSEGLEDIEQLGKKDLEERDFSPADCLVGIAAGGTTPYVK
GGLAYAKEINALAIAISCVPIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDVA
ATNIKLMDRALRILHDLADVDRVRGTELLQASDGSVKVALLMHTCGLDAETAQKLLIEHNNQLRTALARCKNCIA

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=290, Percent_Identity=41.3793103448276, Blast_Score=218, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33663; Mature: 33532

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVFADLNLHPSDNRGHLLTEKVNPKSECLDQLTTESLVTLFCEEDREPQRAVAAAIPE
CCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIQAVEAITDRLRSGGRLFYLGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSAALL
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCHHHH
KSSEGLEDIEQLGKKDLEERDFSPADCLVGIAAGGTTPYVKGGLAYAKEINALAIAISCV
CCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCCHHCCCHHHHHHCCEEEEEEEEE
PIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
ECCCCCCCCEEEEEEECCCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AATNIKLMDRALRILHDLADVDRVRGTELLQASDGSVKVALLMHTCGLDAETAQKLLIEH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCHHHHHHHHHHC
NNQLRTALARCKNCIA
CHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNVFADLNLHPSDNRGHLLTEKVNPKSECLDQLTTESLVTLFCEEDREPQRAVAAAIPE
CCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIQAVEAITDRLRSGGRLFYLGAGTSGRLGVLDAAECPPTFCSDPDLVQGVLAGGSAALL
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCHHHH
KSSEGLEDIEQLGKKDLEERDFSPADCLVGIAAGGTTPYVKGGLAYAKEINALAIAISCV
CCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCCHHCCCHHHHHHCCEEEEEEEEE
PIEQAELPCSIDIRLLTGPELLTGSTRLKAGTATKMALNILSTCAMVRLGKVFGNRMVDV
ECCCCCCCCEEEEEEECCCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AATNIKLMDRALRILHDLADVDRVRGTELLQASDGSVKVALLMHTCGLDAETAQKLLIEH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCHHHHHHHHHHC
NNQLRTALARCKNCIA
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA