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The map label for this gene is abcA [H]

Identifier: 33862381

GI number: 33862381

Start: 123063

End: 124496

Strand: Reverse

Name: abcA [H]

Synonym: PMT0108

Alternate gene names: 33862381

Gene position: 124496-123063 (Counterclockwise)

Preceding gene: 33862382

Following gene: 33862380

Centisome position: 5.16

GC content: 37.03

Gene sequence:

>1434_bases
ATGTATTCAACAACACAACATCAATCTCCTGAAACTGTTGTTACAGTATCATCCTTGGGTAAAGCATATAAAATTTACAA
CAGCAAAAGGGATAGAGCAAAGCAACTAATATTTCAAAATAGACGAAAATATTTTCAAGAGCACTGGGCTCTAAGAAATA
TCAGTTTTGATCTGAGAAGGGGTGAATCAATAGGTATAGTAGGTAAAAATGGAAGCGGTAAAAGTACGTTACTACAACTG
ATATGCGGAACTTTGAAGCCAAGTCAAGGAGAAGTGATAGTAAACGGGAAGATAGCAGCACTTCTAGAACTAGGTAGTGG
GTTTAACCCAGAATTCTCAGGGCGAGAGAATGTGTACCTTAATGCATCGATTCTTGGACTAAATAAACAGGAAATTCAAG
AGCGCCTAGATGATATTCTAGCTTTTGCAGATATAGGAAATTATGTAGATCAACCGGTTAGAACCTACTCAAGCGGAATG
GTTGTAAGGCTTGCATTCTCAGTGATCGCACACGTCGATGCGGACATATTAATCGTGGATGAAGCATTGTCTGTTGGGGA
CGCATATTTCACACAAAAGTGTATGCGGTTTATACAAAGGTTTCAAGAGAAGGGAAGTCTGTTATTTGTTAGCCACGATG
CAAATGCTATTCTAAGTCTTTGCAACAGAGCACTCTTAATTAATCAAGGAGAGCTAAAGCGAGTCGGAAAACCTAAAGAA
GTAATTGAAGACTATACAAGGGATCTACAAAAAAGAAATTTAGCGGATCAGAATAATAAAATAAACAGACCAGAAAGAAT
GAAAGAACAAGAAAACACCGCGCATATGAAAAGACAAAGCGGGGTTCAATACACTCAAAAAAACATAGAGAATGAGATAA
TGAAATGGAGTGACTATCGTTGCAAGCTTATAAATTCAAGCAATCTAGCGAATACAATTGTTATAACCAGATTCGATGAA
ACTTTGACTACACGTGAGACATATGGAGGGGAAAAGGCAGAAATTACTAACGTAGAGTTAGAAAATATAGAGACTAATAA
AACTATTCAAAATATTAAGGGTGGTGAGATTGTAAGATTAAGACTTAAATTTGAAGCCCGCACAGCGATTGGTAGGCCCA
TAATTGGATTCATCCTCAAAAACAGTAAAGGTTTAACAATATTAGGGGATAATACAAATAATTCAATTTCAGAAAATAAT
GATTTCAATGCATTTGAGGGGGATAAAGTAACAACAGACTTTGTCTTTACCGTTCCTATGTTGCAACAAGGAGAGTATAT
GATTTCAGTATCAGTGGCAGATGGATGCATAACAGAACACGAGATCCTTCACTGGATGAATGATGCCTTATTACTGAGGT
CGCAATGCACTAGCATTGCTGCTGGTTTAGCAGGTGTACCAATGCATTCGATAAGCATCGAAATAGAAAAATGA

Upstream 100 bases:

>100_bases
GATTACAGATAGCAGTACAATTTCTAATATCAATTGGCTGGTGTGAAATCACCCTTAGGATTTTAAAAAATGCACAAAGC
GAGTTTGGAGATATACTTTA

Downstream 100 bases:

>100_bases
AAGTACCTGAAAGTCTCAACTTAATTCCAAAGTACTATGCACCATCATCATGGTGGCAACATGTACCAATTGCACACTGG
CTGGTAGAGAATCTTAAACC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MYSTTQHQSPETVVTVSSLGKAYKIYNSKRDRAKQLIFQNRRKYFQEHWALRNISFDLRRGESIGIVGKNGSGKSTLLQL
ICGTLKPSQGEVIVNGKIAALLELGSGFNPEFSGRENVYLNASILGLNKQEIQERLDDILAFADIGNYVDQPVRTYSSGM
VVRLAFSVIAHVDADILIVDEALSVGDAYFTQKCMRFIQRFQEKGSLLFVSHDANAILSLCNRALLINQGELKRVGKPKE
VIEDYTRDLQKRNLADQNNKINRPERMKEQENTAHMKRQSGVQYTQKNIENEIMKWSDYRCKLINSSNLANTIVITRFDE
TLTTRETYGGEKAEITNVELENIETNKTIQNIKGGEIVRLRLKFEARTAIGRPIIGFILKNSKGLTILGDNTNNSISENN
DFNAFEGDKVTTDFVFTVPMLQQGEYMISVSVADGCITEHEILHWMNDALLLRSQCTSIAAGLAGVPMHSISIEIEK

Sequences:

>Translated_477_residues
MYSTTQHQSPETVVTVSSLGKAYKIYNSKRDRAKQLIFQNRRKYFQEHWALRNISFDLRRGESIGIVGKNGSGKSTLLQL
ICGTLKPSQGEVIVNGKIAALLELGSGFNPEFSGRENVYLNASILGLNKQEIQERLDDILAFADIGNYVDQPVRTYSSGM
VVRLAFSVIAHVDADILIVDEALSVGDAYFTQKCMRFIQRFQEKGSLLFVSHDANAILSLCNRALLINQGELKRVGKPKE
VIEDYTRDLQKRNLADQNNKINRPERMKEQENTAHMKRQSGVQYTQKNIENEIMKWSDYRCKLINSSNLANTIVITRFDE
TLTTRETYGGEKAEITNVELENIETNKTIQNIKGGEIVRLRLKFEARTAIGRPIIGFILKNSKGLTILGDNTNNSISENN
DFNAFEGDKVTTDFVFTVPMLQQGEYMISVSVADGCITEHEILHWMNDALLLRSQCTSIAAGLAGVPMHSISIEIEK
>Mature_477_residues
MYSTTQHQSPETVVTVSSLGKAYKIYNSKRDRAKQLIFQNRRKYFQEHWALRNISFDLRRGESIGIVGKNGSGKSTLLQL
ICGTLKPSQGEVIVNGKIAALLELGSGFNPEFSGRENVYLNASILGLNKQEIQERLDDILAFADIGNYVDQPVRTYSSGM
VVRLAFSVIAHVDADILIVDEALSVGDAYFTQKCMRFIQRFQEKGSLLFVSHDANAILSLCNRALLINQGELKRVGKPKE
VIEDYTRDLQKRNLADQNNKINRPERMKEQENTAHMKRQSGVQYTQKNIENEIMKWSDYRCKLINSSNLANTIVITRFDE
TLTTRETYGGEKAEITNVELENIETNKTIQNIKGGEIVRLRLKFEARTAIGRPIIGFILKNSKGLTILGDNTNNSISENN
DFNAFEGDKVTTDFVFTVPMLQQGEYMISVSVADGCITEHEILHWMNDALLLRSQCTSIAAGLAGVPMHSISIEIEK

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=254, Percent_Identity=26.7716535433071, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI31657092, Length=222, Percent_Identity=27.027027027027, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI27477115, Length=262, Percent_Identity=29.3893129770992, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI6005701, Length=220, Percent_Identity=28.1818181818182, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436953, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI27881501, Length=225, Percent_Identity=24, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI30795238, Length=225, Percent_Identity=24, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150417984, Length=265, Percent_Identity=24.5283018867925, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI27262624, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI116734710, Length=206, Percent_Identity=24.2718446601942, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=234, Percent_Identity=25.2136752136752, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789032, Length=253, Percent_Identity=25.296442687747, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789751, Length=235, Percent_Identity=28.5106382978723, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787758, Length=228, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=25.462962962963, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787029, Length=223, Percent_Identity=26.457399103139, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=224, Percent_Identity=22.3214285714286, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788761, Length=218, Percent_Identity=24.3119266055046, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48995001, Length=205, Percent_Identity=25.8536585365854, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788897, Length=205, Percent_Identity=26.3414634146341, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786398, Length=200, Percent_Identity=25.5, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=24.537037037037, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=23.6607142857143, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI48994943, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=293, Percent_Identity=21.5017064846416, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788210, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081782, Length=209, Percent_Identity=23.9234449760766, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693107, Length=245, Percent_Identity=24.8979591836735, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=222, Percent_Identity=24.7747747747748, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=226, Percent_Identity=24.7787610619469, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=220, Percent_Identity=24.0909090909091, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=220, Percent_Identity=24.0909090909091, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=220, Percent_Identity=24.0909090909091, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=192, Percent_Identity=25.5208333333333, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007184, Length=211, Percent_Identity=26.0663507109005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221500365, Length=211, Percent_Identity=26.0663507109005, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643674, Length=274, Percent_Identity=21.1678832116788, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221512771, Length=233, Percent_Identity=21.8884120171674, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574259, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666092, Length=262, Percent_Identity=22.1374045801527, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 53673; Mature: 53673

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00142 ZINC_PROTEASE ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTTQHQSPETVVTVSSLGKAYKIYNSKRDRAKQLIFQNRRKYFQEHWALRNISFDLRR
CCCCCCCCCCCEEEEHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
GESIGIVGKNGSGKSTLLQLICGTLKPSQGEVIVNGKIAALLELGSGFNPEFSGRENVYL
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEE
NASILGLNKQEIQERLDDILAFADIGNYVDQPVRTYSSGMVVRLAFSVIAHVDADILIVD
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
EALSVGDAYFTQKCMRFIQRFQEKGSLLFVSHDANAILSLCNRALLINQGELKRVGKPKE
CHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCEEEECCCCHHHCCCCHH
VIEDYTRDLQKRNLADQNNKINRPERMKEQENTAHMKRQSGVQYTQKNIENEIMKWSDYR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCE
CKLINSSNLANTIVITRFDETLTTRETYGGEKAEITNVELENIETNKTIQNIKGGEIVRL
EEEECCCCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCCEEEE
RLKFEARTAIGRPIIGFILKNSKGLTILGDNTNNSISENNDFNAFEGDKVTTDFVFTVPM
EEEEEHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECH
LQQGEYMISVSVADGCITEHEILHWMNDALLLRSQCTSIAAGLAGVPMHSISIEIEK
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
>Mature Secondary Structure
MYSTTQHQSPETVVTVSSLGKAYKIYNSKRDRAKQLIFQNRRKYFQEHWALRNISFDLRR
CCCCCCCCCCCEEEEHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
GESIGIVGKNGSGKSTLLQLICGTLKPSQGEVIVNGKIAALLELGSGFNPEFSGRENVYL
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEE
NASILGLNKQEIQERLDDILAFADIGNYVDQPVRTYSSGMVVRLAFSVIAHVDADILIVD
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
EALSVGDAYFTQKCMRFIQRFQEKGSLLFVSHDANAILSLCNRALLINQGELKRVGKPKE
CHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCEEEECCCCHHHCCCCHH
VIEDYTRDLQKRNLADQNNKINRPERMKEQENTAHMKRQSGVQYTQKNIENEIMKWSDYR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCE
CKLINSSNLANTIVITRFDETLTTRETYGGEKAEITNVELENIETNKTIQNIKGGEIVRL
EEEECCCCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHCCCCCEEEE
RLKFEARTAIGRPIIGFILKNSKGLTILGDNTNNSISENNDFNAFEGDKVTTDFVFTVPM
EEEEEHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECH
LQQGEYMISVSVADGCITEHEILHWMNDALLLRSQCTSIAAGLAGVPMHSISIEIEK
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]