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The map label for this gene is gluP [H]

Identifier: 308535165

GI number: 308535165

Start: 556190

End: 557014

Strand: Direct

Name: gluP [H]

Synonym: NA

Alternate gene names: 308535165

Gene position: 556190-557014 (Clockwise)

Preceding gene: 197116859

Following gene: 197116861

Centisome position: 12.05

GC content: 64.12

Gene sequence:

>825_bases
ATGAGTTCCACAAAGTGTTCCAGATGCGGAAGACAGATAGATGCCAGGGAGCCTCAGTGCATCTGGTGCGGTGCGCCGCG
TCCAAGCTTCGGCGCCAGGTTCAGAGAGATGCTGCGCGGAGGGCTCGATGCAGGCTTTGTGGTGCAGGCGATCATCGCTG
CCAATGCGCTCTTCTACCTACTCTCGCTGCTGGTGAGCGGCAGGCGCGGGTTCGACATGAACCCCCTGAGCTTCCTGTCG
CCGGACCAGAACAGCTTGCTGCTGCTGGGCGCCACGGGCACGATACCGGTGCTGGAGCTTGGGCGCGTCTGGAGCCTCAT
CTCCGCCAACTACCTGCACGGGGGGCTGCTGCACATCCTTTTCAACATGATGGCGCTGCGCCAGATCGGCCCTTGGGTCA
GTGCGGAGTTCGGCGCGAGCCGCATGTTCGTCATCTATACCTTGAGCGGCGTTGCCGGCTACGTCGCCTCCTTCTTTGCC
GGGATCCCCTTCACCATCGGCGCTTCCGCCTCCGTCTGCGGCCTGATCGGCGCCCTTTTCTATTTCGGCAAGAGCCGCGG
CGGCAATTACGGCGCGGCCGTCTCCCGCGAGGTGAGCGGCTGGCTGATCAGCCTGGTCCTCTTCGGCCTGATCATGCCCG
GCATCAACAACTGGGGGCATGGCGGCGGCGTAGTGGGGGGGATCGTGCTGGCGAAACTCCTGGGGTACCAGGAGCGGAGC
CACGAGAACAGCGCGCACCGCCTGCTGGCGCTGATCTGCGTCGTCGCCACCGTGGCCGTCCTTTGCTATGCCGCCTATTT
TTCCCTCGCCTACCGGTTCAGCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: rhomboid-like membrane protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:
NA

Sequences:

>Translated_274_residues
MSSTKCSRCGRQIDAREPQCIWCGAPRPSFGARFREMLRGGLDAGFVVQAIIAANALFYLLSLLVSGRRGFDMNPLSFLS
PDQNSLLLLGATGTIPVLELGRVWSLISANYLHGGLLHILFNMMALRQIGPWVSAEFGASRMFVIYTLSGVAGYVASFFA
GIPFTIGASASVCGLIGALFYFGKSRGGNYGAAVSREVSGWLISLVLFGLIMPGINNWGHGGGVVGGIVLAKLLGYQERS
HENSAHRLLALICVVATVAVLCYAAYFSLAYRFS
>Mature_273_residues
SSTKCSRCGRQIDAREPQCIWCGAPRPSFGARFREMLRGGLDAGFVVQAIIAANALFYLLSLLVSGRRGFDMNPLSFLSP
DQNSLLLLGATGTIPVLELGRVWSLISANYLHGGLLHILFNMMALRQIGPWVSAEFGASRMFVIYTLSGVAGYVASFFAG
IPFTIGASASVCGLIGALFYFGKSRGGNYGAAVSREVSGWLISLVLFGLIMPGINNWGHGGGVVGGIVLAKLLGYQERSH
ENSAHRLLALICVVATVAVLCYAAYFSLAYRFS

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 29305; Mature: 29173

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTKCSRCGRQIDAREPQCIWCGAPRPSFGARFREMLRGGLDAGFVVQAIIAANALFYL
CCCCCHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LSLLVSGRRGFDMNPLSFLSPDQNSLLLLGATGTIPVLELGRVWSLISANYLHGGLLHIL
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FNMMALRQIGPWVSAEFGASRMFVIYTLSGVAGYVASFFAGIPFTIGASASVCGLIGALF
HHHHHHHHHCCCHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHH
YFGKSRGGNYGAAVSREVSGWLISLVLFGLIMPGINNWGHGGGVVGGIVLAKLLGYQERS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
HENSAHRLLALICVVATVAVLCYAAYFSLAYRFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSTKCSRCGRQIDAREPQCIWCGAPRPSFGARFREMLRGGLDAGFVVQAIIAANALFYL
CCCCHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LSLLVSGRRGFDMNPLSFLSPDQNSLLLLGATGTIPVLELGRVWSLISANYLHGGLLHIL
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FNMMALRQIGPWVSAEFGASRMFVIYTLSGVAGYVASFFAGIPFTIGASASVCGLIGALF
HHHHHHHHHCCCHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHH
YFGKSRGGNYGAAVSREVSGWLISLVLFGLIMPGINNWGHGGGVVGGIVLAKLLGYQERS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
HENSAHRLLALICVVATVAVLCYAAYFSLAYRFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]