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The map label for this gene is etfA [H]

Identifier: 308513330

GI number: 308513330

Start: 3075175

End: 3076197

Strand: Reverse

Name: etfA [H]

Synonym: NA

Alternate gene names: 308513330

Gene position: 3076197-3075175 (Counterclockwise)

Preceding gene: 39997890

Following gene: 39997888

Centisome position: 80.65

GC content: 65.79

Gene sequence:

>1023_bases
ATGCTCGCCGCTTATCGGGGGGTTTGGGTCTTCATTGAGCAGACCGAGGGTGAGCCGGCCAAGGTTTCCTGGGAACTGCT
TGGGGTGGGGGGCGAGCTCGCCCGCAGCCTCGGCACGGAGCTGTGCGCCGTGGTCATCGGCCGCGACGTGGAGCATCTCT
GCCGCGAGTCGTTCGCCTACGGCGCCACCAAGGCCTATCTGCTGGACCAAGAAGTCTTCCTTCACTACCGGACCGAACCC
TACCTGGAAGCCTGCTGCTACCTGATCGGGAAGTACAAGCCCGAGATCATCCTCATGGGCGCCACCGGCATGGGCCGCGA
CCTGGCGGGCGCGGTGGCCACGCGGGTCAAGACCGGCCTGACCGCAGACTGCACCGGGCTGGACGTGGACGACAAGAGGA
ACCTGAAGCAGACCCGCCCCGCCTTCGGCGGGAACATCATGGCCACCATCATGTGCGACCGGTTCCGCCCCCAGATGGCC
ACGGTGCGGCCCCACGTCATGAAGATGCCGGAGCGGATCGAGGGTGCCACGGGCGAGATCGTCCGCGAACAGTGCGCCAT
CAACGAGGCCGACATCCTGACCAAGGTGCTGGAGATCATCCGGGACAAGAAGGGCGACCACGTGGACCTGGCCGGTGCCG
AGTTCATCGTTTCCGGCGGCCGCGGCATGATGGCGCCGGAGAACTTCTCCATCCTCAAGGAACTGGCCGACGAACTGGGC
GGGGTTGTGGGTGCGTCGCGCAGCGCCGTGGACGCCGGCTGGATGCCCCACGAGCGCCAGGTGGGCCAGACGGGCAAGAC
GGTGCGACCCAAGATTTACATCGCCTGCGGGATCTCGGGCGCAATCCAGCACCTGGTGGGGATGCAGGATTCCGACGTGG
TCATCGCCATTAACCGCGACAAGGACGCCCCCATCTTTCAGGTGGCCACCTACGGCATCGTGGGTGACCTGTTCCAGATC
GTCCCGGCCATTACCCAGCGCATCCGGGAGCTGAAGAATCAGGGTCCTGTGACCGGCGGCTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:
NA

Sequences:

>Translated_340_residues
MLAAYRGVWVFIEQTEGEPAKVSWELLGVGGELARSLGTELCAVVIGRDVEHLCRESFAYGATKAYLLDQEVFLHYRTEP
YLEACCYLIGKYKPEIILMGATGMGRDLAGAVATRVKTGLTADCTGLDVDDKRNLKQTRPAFGGNIMATIMCDRFRPQMA
TVRPHVMKMPERIEGATGEIVREQCAINEADILTKVLEIIRDKKGDHVDLAGAEFIVSGGRGMMAPENFSILKELADELG
GVVGASRSAVDAGWMPHERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRDKDAPIFQVATYGIVGDLFQI
VPAITQRIRELKNQGPVTGG
>Mature_340_residues
MLAAYRGVWVFIEQTEGEPAKVSWELLGVGGELARSLGTELCAVVIGRDVEHLCRESFAYGATKAYLLDQEVFLHYRTEP
YLEACCYLIGKYKPEIILMGATGMGRDLAGAVATRVKTGLTADCTGLDVDDKRNLKQTRPAFGGNIMATIMCDRFRPQMA
TVRPHVMKMPERIEGATGEIVREQCAINEADILTKVLEIIRDKKGDHVDLAGAEFIVSGGRGMMAPENFSILKELADELG
GVVGASRSAVDAGWMPHERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRDKDAPIFQVATYGIVGDLFQI
VPAITQRIRELKNQGPVTGG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=301, Percent_Identity=35.8803986710963, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI4503607, Length=302, Percent_Identity=36.4238410596026, Blast_Score=179, Evalue=5e-45,
Organism=Escherichia coli, GI1787990, Length=332, Percent_Identity=30.1204819277108, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786226, Length=234, Percent_Identity=33.7606837606838, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082157, Length=285, Percent_Identity=24.5614035087719, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=299, Percent_Identity=37.4581939799331, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6325261, Length=201, Percent_Identity=40.7960199004975, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17136898, Length=270, Percent_Identity=38.5185185185185, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24652801, Length=270, Percent_Identity=38.5185185185185, Blast_Score=177, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36955; Mature: 36955

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAYRGVWVFIEQTEGEPAKVSWELLGVGGELARSLGTELCAVVIGRDVEHLCRESFAY
CCCEECEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GATKAYLLDQEVFLHYRTEPYLEACCYLIGKYKPEIILMGATGMGRDLAGAVATRVKTGL
CCHHEEEECHHHHEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
TADCTGLDVDDKRNLKQTRPAFGGNIMATIMCDRFRPQMATVRPHVMKMPERIEGATGEI
CCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHHCCCCHHHCCHHHHHCHHHHCCCHHHH
VREQCAINEADILTKVLEIIRDKKGDHVDLAGAEFIVSGGRGMMAPENFSILKELADELG
HHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHH
GVVGASRSAVDAGWMPHERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRD
HHHCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECC
KDAPIFQVATYGIVGDLFQIVPAITQRIRELKNQGPVTGG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAAYRGVWVFIEQTEGEPAKVSWELLGVGGELARSLGTELCAVVIGRDVEHLCRESFAY
CCCEECEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GATKAYLLDQEVFLHYRTEPYLEACCYLIGKYKPEIILMGATGMGRDLAGAVATRVKTGL
CCHHEEEECHHHHEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
TADCTGLDVDDKRNLKQTRPAFGGNIMATIMCDRFRPQMATVRPHVMKMPERIEGATGEI
CCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHHCCCCHHHCCHHHHHCHHHHCCCHHHH
VREQCAINEADILTKVLEIIRDKKGDHVDLAGAEFIVSGGRGMMAPENFSILKELADELG
HHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHH
GVVGASRSAVDAGWMPHERQVGQTGKTVRPKIYIACGISGAIQHLVGMQDSDVVIAINRD
HHHCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECC
KDAPIFQVATYGIVGDLFQIVPAITQRIRELKNQGPVTGG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA