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The map label for this gene is yjdB

Identifier: 30064683

GI number: 30064683

Start: 3497561

End: 3499234

Strand: Reverse

Name: yjdB

Synonym: S3621

Alternate gene names: 30064683

Gene position: 3499234-3497561 (Counterclockwise)

Preceding gene: 30064684

Following gene: 30064682

Centisome position: 76.08

GC content: 49.52

Gene sequence:

>1674_bases
ATGCGCACTTTGTTCGATGGAAACACCGTGATGTTGAAGCGCCTACTAAAAAGACCCTCTTTGAATTTACTCGCCTGGCT
ATTGTTGGCCGCTTTTTATATCTCTATCTGCCTGAATATTGCCTTTTTTAAACAGGTGTTGCAGGCGCTGCCGCTGGATT
CGCTGCATAACGTACTGGTTTTCTTGTCGATGCCGGTTGTCGCTTTCAGCGTGATTAATATTGTCCTGACACTAAGCTCT
TTCTTATGGCTTAATCGACCACTGGCCTGCCTGTTTATTCTGATTGGCGCGGCTGCACAATATTTCATAATGACTTACGG
CATCGTCATCGACCGCTCGATGATTGCCAATATTATTGATACCACTCCAGCAGAAAGTTATGCGCTGATGACACCGCAAA
TGTTATTAACGCTGGGATTCAGCGGCGTGCTTGCTGAGCTGATTGCCTGCTGGCTAAAAATCAAACCTGCCACCTCGCGT
CTGCGCAGTGTTCTTTTCCGTGGAGCCAATATTCTGGTTTCTGTACTGCTGATTTTGCTGGTCGCCGCACTGTTTTATAA
AGACTACGCCTCGTTGTTCCGCAATAACAAAGAGCTGGTGAAATCCTTAAGCCCCTCTAACAGCATTGTTGCCAGCTGGT
CATGGTACTCCCATCAGCGACTGGCAAATCTGCCGCTGGTGCGAATTGGTGAAGACGCGCACCGCAACCCGTTAATGCAG
AACGAAAAACGTAAAAATTTGACCATCCTGATTGTCGGCGAAACCTCGCGGGCGGAGAACTTCTCCCTCAACGGCTACCC
GCGTGAAACTAACCCGCGGCTGGCGAAAGATAACGTGGTCTATTTCCCTAATACCGCATCTTGCGGCACGGCAACGGCAG
TTTCAGTACCGTGCATGTTCTCGGATATGCCGCGTGAGCACTACAAAGAAGAGCTGGCACAGCACCAGGAAGGCGTGCTG
GATATCATTCAGCGAGCGGGCATCAACGTGCTGTGGAATGACAACGATGGCGGCTGTAAAGGTGCCTGCGACCGCGTGCC
TCACCAGAACGTCACCGCGCTGAATCTGCCTGATCAGTGCATCAACGGCGAATGCTATGACGAAGTGCTGTTCCACGGGC
TGGAAGAGTACATCAATAACCTGCAGGGTGATGGCGTGATTGTCTTACACACCATCGGCAGCCACGGTCCGACCTATTAC
AACCGCTATCCGCCGCAGTTCAGGAAATTTACCCCAACCTGCGACACCAATGAGATCCAGACCTGTACCAAAGAGCAACT
GGTGAACACTTACGACAACACGCTGGTTTACGTCGACTATATTGTTGATAAAGCGATTAATCTGCTTAAAGAACATCAGG
ATAAATTTACCACCAGCCTGGTTTATCTTTCTGACCACGGTGAATCGTTAGGTGAAAATGGCATCTATCTGCACGGTCTG
CCTTATGCCATCGCCCCGGATAGCCAAAAACAGGTGCCAATGCTGCTGTGGCTGTCGGAGGATTATCAAAAGCGGTATCA
GGTTGACCAGAACTGCCTGCAAAAACAGGCGCAAACGCAACACTATTCACAAGACAATTTATTCTCCACGCTATTGGGAT
TAACTGGCGTTGAGACGAAGTATTACCAGGCCGCGGATGATATTCTGCAAACTTGCAGGAGAGTGAGTAAATGA

Upstream 100 bases:

>100_bases
TTAGATGCACCAATAAGCAAAGATTAATTCCCCTTAATCCAGCAAACATAAAAGCCAACCTTAAGAACTTAAGGTTGGCT
TAATTTTGCTTTGCGAGCAT

Downstream 100 bases:

>100_bases
AAATTCTGATTGTTGAAGACGATACGCTGTTATTGCAGGGACTGATTCTGGCGGCGCAAACCGAAGGCTACGCGTGCGAT
GGCGTGACAACCGCGCGGAT

Product: putative cell division protein

Products: NA

Alternate protein names: Polymyxin resistance protein pmrC [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRTLFDGNTVMLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLVFLSMPVVAFSVINIVLTLSS
FLWLNRPLACLFILIGAAAQYFIMTYGIVIDRSMIANIIDTTPAESYALMTPQMLLTLGFSGVLAELIACWLKIKPATSR
LRSVLFRGANILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQ
NEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMFSDMPREHYKEELAQHQEGVL
DIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYY
NRYPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGL
PYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSK

Sequences:

>Translated_557_residues
MRTLFDGNTVMLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLVFLSMPVVAFSVINIVLTLSS
FLWLNRPLACLFILIGAAAQYFIMTYGIVIDRSMIANIIDTTPAESYALMTPQMLLTLGFSGVLAELIACWLKIKPATSR
LRSVLFRGANILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQ
NEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMFSDMPREHYKEELAQHQEGVL
DIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYY
NRYPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGL
PYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSK
>Mature_557_residues
MRTLFDGNTVMLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLVFLSMPVVAFSVINIVLTLSS
FLWLNRPLACLFILIGAAAQYFIMTYGIVIDRSMIANIIDTTPAESYALMTPQMLLTLGFSGVLAELIACWLKIKPATSR
LRSVLFRGANILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQ
NEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMFSDMPREHYKEELAQHQEGVL
DIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYY
NRYPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGL
PYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSK

Specific function: Catalyzes the addition of a phosphoethanolamine moiety to the lipid A. The phosphoethanolamine modification is required for resistance to polymyxin [H]

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. EptA subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082372, Length=547, Percent_Identity=99.2687385740402, Blast_Score=1130, Evalue=0.0,
Organism=Escherichia coli, GI87082286, Length=546, Percent_Identity=24.5421245421245, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87082223, Length=462, Percent_Identity=24.8917748917749, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012549
- InterPro:   IPR000917 [H]

Pfam domain/function: PF08019 DUF1705; PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 62874; Mature: 62874

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLFDGNTVMLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLV
CCCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILIGAAAQYFIMTYGIVIDRSMIANIID
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTPAESYALMTPQMLLTLGFSGVLAELIACWLKIKPATSRLRSVLFRGANILVSVLLILL
CCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHH
VAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQ
HHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECHHHHHHHHCCCEEEECCCHHCCCCCC
NEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMF
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHEECCHHH
SDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQC
HCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCEEEECCCHHH
INGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNRYPPQFRKFTPTCDTNEIQ
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCHHH
TCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGL
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEECC
PYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETK
CCEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
YYQAADDILQTCRRVSK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTLFDGNTVMLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLV
CCCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILIGAAAQYFIMTYGIVIDRSMIANIID
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTPAESYALMTPQMLLTLGFSGVLAELIACWLKIKPATSRLRSVLFRGANILVSVLLILL
CCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHH
VAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQ
HHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECHHHHHHHHCCCEEEECCCHHCCCCCC
NEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMF
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHEECCHHH
SDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTALNLPDQC
HCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCEEEECCCHHH
INGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNRYPPQFRKFTPTCDTNEIQ
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCHHH
TCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGL
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEECC
PYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETK
CCEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
YYQAADDILQTCRRVSK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8282725 [H]