Click here to switch to the map view.

The map label for this gene is yhaU

Identifier: 30064466

GI number: 30064466

Start: 3256185

End: 3257519

Strand: Reverse

Name: yhaU

Synonym: S3379

Alternate gene names: 30064466

Gene position: 3257519-3256185 (Counterclockwise)

Preceding gene: 30064468

Following gene: 161486431

Centisome position: 70.83

GC content: 50.64

Gene sequence:

>1335_bases
ATGATTCTGGACACCGTTGACGAAAAAAGGAAAGGTGTGCATACCCGCTATTTAATATTACTGATTATTTTTATTGTTAC
CGCCGTTAACTACGCCGATCGTGCAACGCTGTCTATTGCTGGTACCGAAGTGGCAAAAGAGTTGCAGTTAAGTGCGGTTT
CGATGGGTTACATCTTCTCCGCTTTTGGCTGGGCCTACTTGCTGATGCAAATCCCCGGCGGCTGGTTGCTTGATAAGTTT
GGCTCGAAAAAAGTTTACACCTACAGCCTCTTTTTCTGGTCGCTGTTCACCTTCCTGCAAGGCTTTGTTGATATGTTCCC
GCTGGCTTGGGCAGGGATCTCCATGTTCTTTATGCGCTTTATGCTGGGATTCTCGGAAGCTCCATCCTTCCCGGCGAACG
CCCGTATTGTCGCCGCCTGGTTCCCGACGAAAGAACGTGGTACTGCCTCCGCCATCTTTAACTCGGCACAATATTTCTCG
CTGGCGCTCTTTTCGCCTCTGCTTGGCTGGCTGACTTTCGCCTGGGGATGGGAGCACGTCTTTACCGTTATGGGGGTGAT
TTGTTTTGTGCTGACGGCGCTGTGGATCAAGTTGATTCATAACCCGACAGATCACCCACGTATGTCTGAGGAAGAGCTGA
AGTTTATCTCTGAAAATGGCGCGGTGGTCGATATGGACCACAAAAAGCCGGGCAGCGCGGCAGCAAGCGGTCCCAAACTG
CATTACATCAAGCAATTGCTCTCTAACCGCATGATGTTGGGCGTATTTTTCGGACAATATTTTATCAACACCATCACCTG
GTTCTTCCTCACCTGGTTCCCGATTTATCTGGTGCAGGAAAAAGGCATGTCGATTCTGAAAGTGGGTCTGGTCGCCTCGA
TTCCGGCACTGTGTGGTTTTGCGGGCGGCGTGCTGGGAGGTGTCTTCTCGGATTATCTGATCAAACGCGGTTTATCCCTG
ACCCTGGCACGTAAGCTACCGATTGTGCTGGGAATGTTGCTGGCTTCCACCATCATCTTATGTAACTACACCAACAACAC
CACGCTGGTGGTCATGCTGATGGCGCTGGCTTTTTTTGGCAAAGGATTTGGTGCTCTGGGCTGGCCGGTGATTTCTGACA
CCGCGCCGAAAGAGATTGTTGGCCTCTGTGGCGGCGTCTTTAACGTCTTTGGCAATGTTGCCTCCATTGTCACTCCACTG
GTGATTGGCTACCTGGTAAGTGAACTGCACTCCTTCAATGCAGCACTGGTTTTCGTGGGATGTTCAGCGCTGATGGCGAT
GGTCTGCTACCTCTTCGTAGTTGGCGACATTAAACGTATGGAATTGCAGAAATAA

Upstream 100 bases:

>100_bases
CTAATTCCCGAGTTCATTGTCGTTACGGCATAAATGAAACTTATAAATAACACCTTCCCCATAATAATAAAAATCAGCAT
AAGTACCCGAGGTAAATAAA

Downstream 100 bases:

>100_bases
GCAAAGGTATAAGCGATGAATAACGATGTTTTCCCGAATAAATTCAAAGCCGCACTGGCTGCGAAACAGGTACAAATTGG
TTGCTGGTCAGCACTCTCTA

Product: putative transport protein

Products: NA

Alternate protein names: D-galactarate permease [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MILDTVDEKRKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKF
GSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
LALFSPLLGWLTFAWGWEHVFTVMGVICFVLTALWIKLIHNPTDHPRMSEEELKFISENGAVVDMDHKKPGSAAASGPKL
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSL
TLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPL
VIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK

Sequences:

>Translated_444_residues
MILDTVDEKRKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKF
GSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
LALFSPLLGWLTFAWGWEHVFTVMGVICFVLTALWIKLIHNPTDHPRMSEEELKFISENGAVVDMDHKKPGSAAASGPKL
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSL
TLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPL
VIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK
>Mature_444_residues
MILDTVDEKRKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKF
GSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
LALFSPLLGWLTFAWGWEHVFTVMGVICFVLTALWIKLIHNPTDHPRMSEEELKFISENGAVVDMDHKKPGSAAASGPKL
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSL
TLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPL
VIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK

Specific function: Uptake of D-galactarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=392, Percent_Identity=25.2551020408163, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI21322234, Length=420, Percent_Identity=24.2857142857143, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI9966811, Length=433, Percent_Identity=22.8637413394919, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI148743791, Length=375, Percent_Identity=25.8666666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI6912666, Length=425, Percent_Identity=23.7647058823529, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4885441, Length=377, Percent_Identity=27.3209549071618, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI5031955, Length=337, Percent_Identity=27.299703264095, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI154350196, Length=417, Percent_Identity=23.9808153477218, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI148728191, Length=313, Percent_Identity=25.2396166134185, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI223718438, Length=222, Percent_Identity=25.2252252252252, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI256219598, Length=398, Percent_Identity=21.8592964824121, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4503847, Length=398, Percent_Identity=21.8592964824121, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI256219483, Length=398, Percent_Identity=21.8592964824121, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789515, Length=444, Percent_Identity=99.3243243243243, Blast_Score=891, Evalue=0.0,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=57.5688073394495, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI87082320, Length=438, Percent_Identity=40.1826484018265, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI2367379, Length=420, Percent_Identity=30.4761904761905, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI2367193, Length=408, Percent_Identity=25.4901960784314, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788573, Length=438, Percent_Identity=23.7442922374429, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=437, Percent_Identity=26.3157894736842, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115533554, Length=434, Percent_Identity=26.2672811059908, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17552542, Length=377, Percent_Identity=24.6684350132626, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535049, Length=419, Percent_Identity=23.6276849642005, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560030, Length=403, Percent_Identity=22.5806451612903, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570335, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=351, Percent_Identity=24.7863247863248, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=283, Percent_Identity=24.3816254416961, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=289, Percent_Identity=22.4913494809689, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25151055, Length=247, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71991448, Length=210, Percent_Identity=29.5238095238095, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=404, Percent_Identity=19.8019801980198, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=274, Percent_Identity=21.1678832116788, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=338, Percent_Identity=23.6686390532544, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=404, Percent_Identity=19.8019801980198, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=375, Percent_Identity=19.7333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24654215, Length=468, Percent_Identity=23.5042735042735, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922400, Length=460, Percent_Identity=23.9130434782609, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24648416, Length=459, Percent_Identity=24.6187363834423, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356189, Length=459, Percent_Identity=24.6187363834423, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24639764, Length=422, Percent_Identity=23.9336492890995, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI20130135, Length=426, Percent_Identity=25.1173708920188, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655271, Length=423, Percent_Identity=24.822695035461, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45550460, Length=414, Percent_Identity=25.1207729468599, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24583789, Length=413, Percent_Identity=25.6658595641646, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641682, Length=405, Percent_Identity=22.4691358024691, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28573708, Length=475, Percent_Identity=24.4210526315789, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573707, Length=475, Percent_Identity=24.4210526315789, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584153, Length=430, Percent_Identity=24.4186046511628, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655255, Length=375, Percent_Identity=25.0666666666667, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24653727, Length=372, Percent_Identity=25.5376344086022, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20130167, Length=469, Percent_Identity=24.0938166311301, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62484226, Length=389, Percent_Identity=25.4498714652956, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45550364, Length=453, Percent_Identity=25.3863134657837, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129235, Length=395, Percent_Identity=25.5696202531646, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24658658, Length=449, Percent_Identity=24.4988864142539, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580790, Length=381, Percent_Identity=24.1469816272966, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573299, Length=427, Percent_Identity=25.5269320843091, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658689, Length=447, Percent_Identity=24.1610738255034, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45552797, Length=418, Percent_Identity=24.4019138755981, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49142; Mature: 49142

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDTVDEKRKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFS
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
AFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRF
HHHHHHHHHHCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHV
HHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVMGVICFVLTALWIKLIHNPTDHPRMSEEELKFISENGAVVDMDHKKPGSAAASGPKL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHH
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHC
KGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CSALMAMVCYLFVVGDIKRMELQK
HHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MILDTVDEKRKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFS
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
AFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRF
HHHHHHHHHHCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHV
HHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVMGVICFVLTALWIKLIHNPTDHPRMSEEELKFISENGAVVDMDHKKPGSAAASGPKL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHH
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHC
KGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CSALMAMVCYLFVVGDIKRMELQK
HHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]