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The map label for this gene is pheA [H]

Identifier: 29349344

GI number: 29349344

Start: 5110336

End: 5111184

Strand: Reverse

Name: pheA [H]

Synonym: BT_3936

Alternate gene names: 29349344

Gene position: 5111184-5110336 (Counterclockwise)

Preceding gene: 29349345

Following gene: 29349343

Centisome position: 81.64

GC content: 45.94

Gene sequence:

>849_bases
ATGAAAAAGATAGCAATTCAAGGAACACTCGGCTCATATCACGATATCGCCGCACACAAGTACTTCGAGGGAGAAGAAAT
AGAGTTAATCTGTTGTGCCAACTTCGAAGACGTGTTTACTTCGATACGGAAAGACAGCCAGGTCATCGGAATGCTAGCCA
TCGAAAATACGATAGCGGGAAGCCTGCTGCACAACAATGAACTGTTGAGACAAAGCGGTACGCAGATTATCGGCGAATAC
AAGCTGCGCATCTCACATAGCTTCGTCTGCCTGCCCGAAGAAAGCTGGGAAGACCTGACAGAAGTCAACTCCCACCCTAT
CGCCCTGATGCAATGCCGTGATTTTCTGAATCAGCATCCGCAACTCAAAGTAGTGGAAGGAGAAGATACGGCACGCAGCG
CGGAAATCATCAAGAAAGAAAACCTGAAAGGGCATGCAGCCATTTGCTCGAAAACGGCGGCAGAACGCTACGGAATGAAA
GTGCTCCAAGAAGGCATCGAAACCAACAAGCACAACTTCACCCGTTTTCTGGTAGTTGCCGATCCGTGGCAAGTGGACGA
ACTCCGCCAGCATCACGCAAAGGCGACCAACAAGGCAAGCATGGTATTCACATTGCCACACACAGAAGGAAGCCTGTCGC
AAGTATTATCCATTCTTTCGTTCTACAACATCAATCTGACAAAGATACAATCGCTGCCGATCATCGGACGGGAATGGGAA
TATCAGTTTTACGTCGATGTATCTTTCAATGATTATCTGAGATATAAACAATCTATAGCAGCAATTACTCCATTAACCAA
AGAACTTAAAATATTAGGCGAATATGCAGAAGGAAAGTCAAACGTATAA

Upstream 100 bases:

>100_bases
TCAAGTGACATGATGCTTAAGGACTGAGATGAAGAAATTAATCATATAAATCCCGCTTCCATATGGACGCGGGATTTTTT
TATATAACCCTATTAGAACA

Downstream 100 bases:

>100_bases
AATCGCTCCTGCCGAAAGACTGGCAAGTGTCAGCGAATACTACTTCTCAAAGAAGCTGAAAGAGGTAGCACAAATGAATG
CAGAAGGAAAAGACGTTATC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKKIAIQGTLGSYHDIAAHKYFEGEEIELICCANFEDVFTSIRKDSQVIGMLAIENTIAGSLLHNNELLRQSGTQIIGEY
KLRISHSFVCLPEESWEDLTEVNSHPIALMQCRDFLNQHPQLKVVEGEDTARSAEIIKKENLKGHAAICSKTAAERYGMK
VLQEGIETNKHNFTRFLVVADPWQVDELRQHHAKATNKASMVFTLPHTEGSLSQVLSILSFYNINLTKIQSLPIIGREWE
YQFYVDVSFNDYLRYKQSIAAITPLTKELKILGEYAEGKSNV

Sequences:

>Translated_282_residues
MKKIAIQGTLGSYHDIAAHKYFEGEEIELICCANFEDVFTSIRKDSQVIGMLAIENTIAGSLLHNNELLRQSGTQIIGEY
KLRISHSFVCLPEESWEDLTEVNSHPIALMQCRDFLNQHPQLKVVEGEDTARSAEIIKKENLKGHAAICSKTAAERYGMK
VLQEGIETNKHNFTRFLVVADPWQVDELRQHHAKATNKASMVFTLPHTEGSLSQVLSILSFYNINLTKIQSLPIIGREWE
YQFYVDVSFNDYLRYKQSIAAITPLTKELKILGEYAEGKSNV
>Mature_282_residues
MKKIAIQGTLGSYHDIAAHKYFEGEEIELICCANFEDVFTSIRKDSQVIGMLAIENTIAGSLLHNNELLRQSGTQIIGEY
KLRISHSFVCLPEESWEDLTEVNSHPIALMQCRDFLNQHPQLKVVEGEDTARSAEIIKKENLKGHAAICSKTAAERYGMK
VLQEGIETNKHNFTRFLVVADPWQVDELRQHHAKATNKASMVFTLPHTEGSLSQVLSILSFYNINLTKIQSLPIIGREWE
YQFYVDVSFNDYLRYKQSIAAITPLTKELKILGEYAEGKSNV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=280, Percent_Identity=31.7857142857143, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31991; Mature: 31991

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAIQGTLGSYHDIAAHKYFEGEEIELICCANFEDVFTSIRKDSQVIGMLAIENTIAG
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHH
SLLHNNELLRQSGTQIIGEYKLRISHSFVCLPEESWEDLTEVNSHPIALMQCRDFLNQHP
HHHHCHHHHHHCCCCEEEEEEEEEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCC
QLKVVEGEDTARSAEIIKKENLKGHAAICSKTAAERYGMKVLQEGIETNKHNFTRFLVVA
CEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
DPWQVDELRQHHAKATNKASMVFTLPHTEGSLSQVLSILSFYNINLTKIQSLPIIGREWE
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEE
YQFYVDVSFNDYLRYKQSIAAITPLTKELKILGEYAEGKSNV
EEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKIAIQGTLGSYHDIAAHKYFEGEEIELICCANFEDVFTSIRKDSQVIGMLAIENTIAG
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHH
SLLHNNELLRQSGTQIIGEYKLRISHSFVCLPEESWEDLTEVNSHPIALMQCRDFLNQHP
HHHHCHHHHHHCCCCEEEEEEEEEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCC
QLKVVEGEDTARSAEIIKKENLKGHAAICSKTAAERYGMKVLQEGIETNKHNFTRFLVVA
CEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
DPWQVDELRQHHAKATNKASMVFTLPHTEGSLSQVLSILSFYNINLTKIQSLPIIGREWE
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEE
YQFYVDVSFNDYLRYKQSIAAITPLTKELKILGEYAEGKSNV
EEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]