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The map label for this gene is lytS [H]

Identifier: 29346676

GI number: 29346676

Start: 1572943

End: 1573998

Strand: Reverse

Name: lytS [H]

Synonym: BT_1266

Alternate gene names: 29346676

Gene position: 1573998-1572943 (Counterclockwise)

Preceding gene: 29346677

Following gene: 29346675

Centisome position: 25.14

GC content: 41.19

Gene sequence:

>1056_bases
ATGAAAAGAGCCAACTGTATGAATGTAAAGTTGAACACCTTATTGTATATAGCGCTGTTTTCAGGATTGGGTATATTCTC
TTTCCTGTTACTGATAAATTATGCAACCTTCTCTGATCGGGTTGCCGATATGCTACATTCAGTCAGTACACTGGGGTTCT
TCATACTGGCTTTTAATGTGCTGGGATATACTACCATCAGGCTGAGTTCATGGATTGATAATCAGTATGCGTTGAATCTG
CATCGGCGTTGGAAGCTGGTTTCAGTCTATATTATCGTAATGGGGATGTTTCTTTTGCTGAACTACGGTTTAATGGTAAC
TGCCAAGTTGTTGGCAGGAGCTTCTTATCCGTTTACGTTTCCCAACGGAGGCTGGCGGATTCTTATAACTGTATGGCTGG
TAGAGCTCGTCATCCTTGGATTGTTGCTGGCCAATCGTTCCATGCGTAATACGTTAAGATTACAACAGAAAGCGGCTGCC
TTGCAAAAAGAGAATAATACGGCACGCTATACAGCTCTACAGAATCAGTTGAATCCTCATTTCTTGTTTAACAGTCTGAA
TACCTTGATTTCTGAGATTCGCTACAATCCGGCTAATGCGGAATTGTTCACCCAGCATCTTTCGGATGTGTATCGCTATA
TTCTTCAGTGTCAGAATCAAAGGCTGACAACACTGCGAGAGGAAATGGATTTTCTGAACTCTTATATTTTTCTGCATAGG
GTTCGTTTGGGCGATTGCATTCATATTGACAACCGTATTCCGAAGACTTGTATGGAGGCTCAGTTGCCTCCGCTTACTAT
TCAATTGTTAGCGGAGAATGTAATCAAACATAATGTCATTCATACGGGAAAACCGATGACTATCGAACTTCTTTATATGG
AAAAGGAACGGGAACTGATCGTCAGAAACCGGATACAAACTAAAAAAACAGTGGTAACTTCCGGAATGGGACTTAAGAAC
CTTTCTGCCCGATATATGTTGTTGTGCAACCGTGACATTGTGGTAGAAAATGACCGGAAAGAGTTTACCGTAAAAATACC
TTTGCTCTATGAATAA

Upstream 100 bases:

>100_bases
GTGAATTATGTACAAGCCAAAGCTGCGGCACAAGGACACTATTCGGAGTTAATAAAAGCGCTCCACGGATATGATTGTCG
ATAAAAAGCACTAACTTTGT

Downstream 100 bases:

>100_bases
GATAAAAGCAGCCATCATAGAAGATGAAATTCCGGCAGCCCGTCTGCTGAGGGATACGTTATTGTCTCTTCGTCCCGATT
GGGAGGTACAGTTATTGCCC

Product: two-component system sensor

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKRANCMNVKLNTLLYIALFSGLGIFSFLLLINYATFSDRVADMLHSVSTLGFFILAFNVLGYTTIRLSSWIDNQYALNL
HRRWKLVSVYIIVMGMFLLLNYGLMVTAKLLAGASYPFTFPNGGWRILITVWLVELVILGLLLANRSMRNTLRLQQKAAA
LQKENNTARYTALQNQLNPHFLFNSLNTLISEIRYNPANAELFTQHLSDVYRYILQCQNQRLTTLREEMDFLNSYIFLHR
VRLGDCIHIDNRIPKTCMEAQLPPLTIQLLAENVIKHNVIHTGKPMTIELLYMEKERELIVRNRIQTKKTVVTSGMGLKN
LSARYMLLCNRDIVVENDRKEFTVKIPLLYE

Sequences:

>Translated_351_residues
MKRANCMNVKLNTLLYIALFSGLGIFSFLLLINYATFSDRVADMLHSVSTLGFFILAFNVLGYTTIRLSSWIDNQYALNL
HRRWKLVSVYIIVMGMFLLLNYGLMVTAKLLAGASYPFTFPNGGWRILITVWLVELVILGLLLANRSMRNTLRLQQKAAA
LQKENNTARYTALQNQLNPHFLFNSLNTLISEIRYNPANAELFTQHLSDVYRYILQCQNQRLTTLREEMDFLNSYIFLHR
VRLGDCIHIDNRIPKTCMEAQLPPLTIQLLAENVIKHNVIHTGKPMTIELLYMEKERELIVRNRIQTKKTVVTSGMGLKN
LSARYMLLCNRDIVVENDRKEFTVKIPLLYE
>Mature_351_residues
MKRANCMNVKLNTLLYIALFSGLGIFSFLLLINYATFSDRVADMLHSVSTLGFFILAFNVLGYTTIRLSSWIDNQYALNL
HRRWKLVSVYIIVMGMFLLLNYGLMVTAKLLAGASYPFTFPNGGWRILITVWLVELVILGLLLANRSMRNTLRLQQKAAA
LQKENNTARYTALQNQLNPHFLFNSLNTLISEIRYNPANAELFTQHLSDVYRYILQCQNQRLTTLREEMDFLNSYIFLHR
VRLGDCIHIDNRIPKTCMEAQLPPLTIQLLAENVIKHNVIHTGKPMTIELLYMEKERELIVRNRIQTKKTVVTSGMGLKN
LSARYMLLCNRDIVVENDRKEFTVKIPLLYE

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=133, Percent_Identity=33.8345864661654, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788723, Length=124, Percent_Identity=33.8709677419355, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40633; Mature: 40633

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRANCMNVKLNTLLYIALFSGLGIFSFLLLINYATFSDRVADMLHSVSTLGFFILAFNV
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYTTIRLSSWIDNQYALNLHRRWKLVSVYIIVMGMFLLLNYGLMVTAKLLAGASYPFTF
HHHHHEEHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PNGGWRILITVWLVELVILGLLLANRSMRNTLRLQQKAAALQKENNTARYTALQNQLNPH
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHH
FLFNSLNTLISEIRYNPANAELFTQHLSDVYRYILQCQNQRLTTLREEMDFLNSYIFLHR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VRLGDCIHIDNRIPKTCMEAQLPPLTIQLLAENVIKHNVIHTGKPMTIELLYMEKERELI
HHCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHCCEECCCCCEEEEEEECCHHHHH
VRNRIQTKKTVVTSGMGLKNLSARYMLLCNRDIVVENDRKEFTVKIPLLYE
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEEEEEEEC
>Mature Secondary Structure
MKRANCMNVKLNTLLYIALFSGLGIFSFLLLINYATFSDRVADMLHSVSTLGFFILAFNV
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYTTIRLSSWIDNQYALNLHRRWKLVSVYIIVMGMFLLLNYGLMVTAKLLAGASYPFTF
HHHHHEEHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PNGGWRILITVWLVELVILGLLLANRSMRNTLRLQQKAAALQKENNTARYTALQNQLNPH
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHH
FLFNSLNTLISEIRYNPANAELFTQHLSDVYRYILQCQNQRLTTLREEMDFLNSYIFLHR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VRLGDCIHIDNRIPKTCMEAQLPPLTIQLLAENVIKHNVIHTGKPMTIELLYMEKERELI
HHCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHCCEECCCCCEEEEEEECCHHHHH
VRNRIQTKKTVVTSGMGLKNLSARYMLLCNRDIVVENDRKEFTVKIPLLYE
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA