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The map label for this gene is serC [H]

Identifier: 29346563

GI number: 29346563

Start: 1438046

End: 1439113

Strand: Reverse

Name: serC [H]

Synonym: BT_1153

Alternate gene names: 29346563

Gene position: 1439113-1438046 (Counterclockwise)

Preceding gene: 29346564

Following gene: 29346562

Centisome position: 22.99

GC content: 43.82

Gene sequence:

>1068_bases
ATGAAAAAGCATAATTTCAATGCAGGACCTTCCATTCTTCCGCGTGAGGTGATAGAGGATACAGCGAAGGCTATTTTAGA
TTTCAACGGCTCTGGTCTCTCCCTGATGGAAATCAGTCACCGTGCCAAAGACTTCCAACCTGTGGTTGACGAAGCAGAGG
CATTATTCAAGGAATTACTCAATATCCCCGAAGGTTATTCGGTACTGTTCCTTGGTGGTGGTGCTAGTATGGAGTTCTGC
ATGGTACCTTTCAACTTCCTTGAAAAAAAGGCTGCTTATCTGAATACAGGTGTGTGGGCAAAGAAAGCAATGAAAGAAGC
TAAGGGGTTTGGTGAAGTCGTAGAAGTTGCTTCTTCCGCTGAAGCTACATATACTTACATCCCGAAAGATTACACAATTC
CTGCTGACGCAGATTATTTCCACATAACTACCAATAACACGATTTACGGTACAGAATTAAAAGAAGATCTCAATTCTCCG
GTTCCGATGGTTGCCGATATGTCTTCTGATATTTTCTCTCGTCCGATCGACGTATCCAAATATATCTGTATCTATGGTGG
TGCGCAGAAAAATCTGGCTCCTGCCGGTGTTACATTTGTTATCGTGAAGAATGATGCGGTAGGTAAAGTTTCTCGTTACA
TCCCGTCAATGCTGAACTATCAGACTCATATCGATAACGGTTCTATGTTCAACACTCCTCCGGTAGTGCCTATCTATGCT
GCACTGTTGAACCTGCGTTGGATTAAGGCACAGGGTGGTGTGAAAGAAATGGAACGTCGTGCTATCGAAAAGGCTGATAT
GCTGTACGCTGAAATCGACCGTAACAAACTGTTCGTAGGTACTGCTGCCAAAGAAGACCGTTCACGCATGAACATCTGTT
TCGTGATGGCTCCCGAATACAAGGATCTGGAAGCTGACTTCATGAAGTTCGCTACAGAAAAAGGTATGGTAGGTATCAAA
GGACATCGTTCAGTGGGTGGTTTCCGTGCATCTTGCTACAATGCTCTGCCGAAAGAAAGTGTACAAGCTTTGATCGACTG
CATGCAGGAATTTGAAAAACTTCATTAA

Upstream 100 bases:

>100_bases
ATTTTTATAAGGAAAGATTTGTGCACCGGAAATAAATTCGTAAATTCGCAAGGTCAAAAGACATAAACTAACGAAATGTT
AAACCAAAAACAAACTTCAA

Downstream 100 bases:

>100_bases
TAATATAAATAGAGTCACCACAGATTGCACGGATTTACACTGAAATCTTATTGAATATAGTGTGTAGGCCGGTGAAGTCT
GTGGTGAATCTTTTTTAAAA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKKHNFNAGPSILPREVIEDTAKAILDFNGSGLSLMEISHRAKDFQPVVDEAEALFKELLNIPEGYSVLFLGGGASMEFC
MVPFNFLEKKAAYLNTGVWAKKAMKEAKGFGEVVEVASSAEATYTYIPKDYTIPADADYFHITTNNTIYGTELKEDLNSP
VPMVADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPSMLNYQTHIDNGSMFNTPPVVPIYA
ALLNLRWIKAQGGVKEMERRAIEKADMLYAEIDRNKLFVGTAAKEDRSRMNICFVMAPEYKDLEADFMKFATEKGMVGIK
GHRSVGGFRASCYNALPKESVQALIDCMQEFEKLH

Sequences:

>Translated_355_residues
MKKHNFNAGPSILPREVIEDTAKAILDFNGSGLSLMEISHRAKDFQPVVDEAEALFKELLNIPEGYSVLFLGGGASMEFC
MVPFNFLEKKAAYLNTGVWAKKAMKEAKGFGEVVEVASSAEATYTYIPKDYTIPADADYFHITTNNTIYGTELKEDLNSP
VPMVADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPSMLNYQTHIDNGSMFNTPPVVPIYA
ALLNLRWIKAQGGVKEMERRAIEKADMLYAEIDRNKLFVGTAAKEDRSRMNICFVMAPEYKDLEADFMKFATEKGMVGIK
GHRSVGGFRASCYNALPKESVQALIDCMQEFEKLH
>Mature_355_residues
MKKHNFNAGPSILPREVIEDTAKAILDFNGSGLSLMEISHRAKDFQPVVDEAEALFKELLNIPEGYSVLFLGGGASMEFC
MVPFNFLEKKAAYLNTGVWAKKAMKEAKGFGEVVEVASSAEATYTYIPKDYTIPADADYFHITTNNTIYGTELKEDLNSP
VPMVADMSSDIFSRPIDVSKYICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPSMLNYQTHIDNGSMFNTPPVVPIYA
ALLNLRWIKAQGGVKEMERRAIEKADMLYAEIDRNKLFVGTAAKEDRSRMNICFVMAPEYKDLEADFMKFATEKGMVGIK
GHRSVGGFRASCYNALPKESVQALIDCMQEFEKLH

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=40.8839779005525, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI10863955, Length=359, Percent_Identity=36.4902506963788, Blast_Score=227, Evalue=1e-59,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=44.4134078212291, Blast_Score=298, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17506897, Length=363, Percent_Identity=39.3939393939394, Blast_Score=267, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6324758, Length=385, Percent_Identity=35.5844155844156, Blast_Score=215, Evalue=8e-57,
Organism=Drosophila melanogaster, GI21356589, Length=358, Percent_Identity=40.7821229050279, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39435; Mature: 39435

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHNFNAGPSILPREVIEDTAKAILDFNGSGLSLMEISHRAKDFQPVVDEAEALFKELL
CCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHH
NIPEGYSVLFLGGGASMEFCMVPFNFLEKKAAYLNTGVWAKKAMKEAKGFGEVVEVASSA
CCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCC
EATYTYIPKDYTIPADADYFHITTNNTIYGTELKEDLNSPVPMVADMSSDIFSRPIDVSK
CCEEEECCCCCCCCCCCCEEEEEECCEEEECHHHHHHCCCCCEECCCCHHHHCCCCCCCE
YICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPSMLNYQTHIDNGSMFNTPPVVPIYA
EEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHH
ALLNLRWIKAQGGVKEMERRAIEKADMLYAEIDRNKLFVGTAAKEDRSRMNICFVMAPEY
HHHHCEEEECCCCHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCEEEEECCCC
KDLEADFMKFATEKGMVGIKGHRSVGGFRASCYNALPKESVQALIDCMQEFEKLH
CCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKHNFNAGPSILPREVIEDTAKAILDFNGSGLSLMEISHRAKDFQPVVDEAEALFKELL
CCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHH
NIPEGYSVLFLGGGASMEFCMVPFNFLEKKAAYLNTGVWAKKAMKEAKGFGEVVEVASSA
CCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCC
EATYTYIPKDYTIPADADYFHITTNNTIYGTELKEDLNSPVPMVADMSSDIFSRPIDVSK
CCEEEECCCCCCCCCCCCEEEEEECCEEEECHHHHHHCCCCCEECCCCHHHHCCCCCCCE
YICIYGGAQKNLAPAGVTFVIVKNDAVGKVSRYIPSMLNYQTHIDNGSMFNTPPVVPIYA
EEEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHH
ALLNLRWIKAQGGVKEMERRAIEKADMLYAEIDRNKLFVGTAAKEDRSRMNICFVMAPEY
HHHHCEEEECCCCHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCEEEEECCCC
KDLEADFMKFATEKGMVGIKGHRSVGGFRASCYNALPKESVQALIDCMQEFEKLH
CCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA