Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 29144291

GI number: 29144291

Start: 4176570

End: 4177247

Strand: Direct

Name: rpe [H]

Synonym: t4023

Alternate gene names: 29144291

Gene position: 4176570-4177247 (Clockwise)

Preceding gene: 29144290

Following gene: 29144292

Centisome position: 87.16

GC content: 53.69

Gene sequence:

>678_bases
ATGAAACAGTATTTGATTGCCCCCTCAATTCTGTCGGCTGATTTTGCTCGCCTGGGTGAAGACACCGCCAAAGCGCTGGC
TGCCGGTGCTGATGTTGTACACTTTGACGTCATGGATAATCACTATGTGCCGAACCTGACTATCGGCCCGATGGTGCTGA
AATCCCTGCGTCAGTACGGTATTACCGCGCCTATTGATGTCCACCTGATGGTCAAGCCGGTTGACCGTATCGTGCCCGAC
TTTGCCGCCGCTGGCGCGAGCATCATTACCTTTCACCCGGAAGCCTCCGAACATGTTGACCGCACGCTACAGCTGATTAA
AGAGCACGGCTGTAAAGCGGGGCTGGTATTCAACCCGGCAACGTCGCTCAGTTATCTCGATTACGTCATGGACAAACTGG
ATGTGATCCTGCTGATGTCCGTGAACCCAGGCTTCGGCGGCCAGTCTTTTATTCCGCAGACGCTGGATAAACTGCGCGAA
GTGCGTCGCCGCATTGATGCGTCCGGTTACGACATTCGCCTGGAAGTGGACGGCGGCGTGAAGGTGAACAATATCGGCGA
GATCGCCGCAGCTGGTGCGGACATGTTTGTTGCGGGGTCGGCAATTTTCGATAAACCCGACTACAAAAAAGTGATTGATG
AAATGCGCAGTGAGCTGGCAAAGGTAAGTCATGAATAA

Upstream 100 bases:

>100_bases
GCAGCAACGGCGGCACACGTAAAAAGGTGGACGAACTGCTGGCTCTGTACCAACCAGGAGTCGCAACGCCTGCAAGAAAA
TAATTCTCAAGGAGAAGCGG

Downstream 100 bases:

>100_bases
GTTGCAGAATATTCGGGGCGTCGCCTTTGATCTTGACGGTACGCTGGTGGATAGCGCGCCGGGTCTTGCCGCGGCGGTGG
ATATGGCGCTGTATGCGCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHE

Sequences:

>Translated_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHE
>Mature_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPATSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHE

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=221, Percent_Identity=40.2714932126697, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI219879828, Length=221, Percent_Identity=38.9140271493213, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI24307923, Length=177, Percent_Identity=32.7683615819209, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789788, Length=225, Percent_Identity=97.3333333333333, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=37.5634517766497, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=28.7735849056604, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=41.0138248847926, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=233, Percent_Identity=39.0557939914163, Blast_Score=160, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=40.1869158878505, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24540; Mature: 24540

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDASGYDIRLEVDGGV
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHE
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRQYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDASGYDIRLEVDGGV
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSELAKVSHE
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]