Definition Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome.
Accession NC_004631
Length 4,791,961

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The map label for this gene is glnE [H]

Identifier: 29143462

GI number: 29143462

Start: 3207036

End: 3209879

Strand: Reverse

Name: glnE [H]

Synonym: t3121

Alternate gene names: 29143462

Gene position: 3209879-3207036 (Counterclockwise)

Preceding gene: 29143463

Following gene: 29143461

Centisome position: 66.98

GC content: 57.38

Gene sequence:

>2844_bases
ATGACGCCGCTCTCTTCACCCTTATCGCAGTACTGGCAGACCGTTGTTGAGCGCCTACCAGAAGGATTTACTGAGACATC
GCTTAGCGCGCAGGCGAAGTCAGTGCTTACATTTAGCGATTTTGCGCTGGATAGCGTGATAGCGCATCCGGAGTGGCTTG
CCGAACTGGAATCCGCATCGCCGCAGGCTGATGAATGGCGACATTACGCTGGCTGGTTACAGGAGGCGTTGGCAGGTGTC
TGTGACGACGCCTCGCTGATGCGTGAGCTGAGGCTTTTTCGTCGTCGCATCATGGTACGCATCGCCTGGGCACAGACGCT
GTCGCTGGTGGACGATGAGACTATTTTACAACAGTTGAGCCATCTGGCGGAGACGCTCATCGTCGGGGCGCGCGACTGGC
TGTATGCCGCCTGTTGCCGCGAATGGGGAACCCCCTGTAACCCGCAGGGCGTTCCGCAGCCGCTGCTGATTTTAGGCATG
GGCAAGCTGGGCGGCGGCGAACTGAATTTTTCGTCTGATATCGATCTGATTTTCGCCTGGCCGGAACATGGCGAGACCCG
GGGCGGGCGTCGTGAACTCGATAACGCCCAGTTTTTTACGCGTCTCGGGCAGCGGCTGATCAAAGCGCTGGATCAGCCCA
CAATGGATGGTTTTGTCTATCGGGTAGACATGCGCCTGCGACCGTTTGGCGACAGCGGCCCGCTGGTACTGAGTTTTGCC
GCGCTGGAGGATTACTATCAGGAGCAAGGACGCGACTGGGAACGCTACGCCATGGTGAAAGCGCGGCTAATGGGCGATAA
CGACGACGCCTGGTCTCGTGAATTACGCGCCATGCTGCGGCCTTTCGTTTTCCGCCGCTATATCGATTTCAGCGTCATCC
AGTCGCTACGTAATATGAAAGGGATGATCGCCCGCGAAGTGCGACGCCGCGGTTTGAAAGACAACATTAAACTTGGCGCG
GGCGGTATTCGGGAAATTGAGTTTATCGTGCAGGTATTCCAGCTGATCCGCGGCGGACGCGAGCCGTCGCTACAGTCGCG
TTCGTTACTGCCGACGCTGGATGCTATCGCTGCGCTGCATTTGCTGCCTGAGAATGACGTGGCGCAACTACGCGTGGCCT
ATCTTTTTCTACGTCGTCTGGAGAATCTGCTGCAAAGCATCAATGACGAACAGACGCAAACGTTGCCTGCCGACGATCTG
AATCGGGCGCGGCTGGCCTGGGGAATGAAGGCGGAGAACTGGCCGCAGCTTGTTGGCGAACTGACGGATCATATGGCTAA
TGTACGCCGCGTATTCAACGAATTAATTGGCGATGATGAAGCCGATACCCCGCAGGAGGAAGAACGTTCAGAGCCGTGGC
GTGAAGTATGGCAGGATGCGCTACAGGAGGATGATTCGACGCCAGTGCTGGCGCATTTAGCCGATGAGGATCGGCGACAG
GTTCTGACCCTTATCGCTGACTTCCGTAAGGAACTGGATAAACGCCCTATCGGCCCGCGCGGGCGGCAGGTGCTGGACCA
ACTGATGCCGCACCTGCTTGCTGACGTCTGTTCCCGCGAAGACGCCGCTGTTACGCTATCGCGGATAACGCCGTTGCTGG
CGGGGATTGTCACTCGCACCACCTATCTGGAGCTGCTGAGCGAATTTCCCGGCGCGCTGAAACACCTGATTATGCTCTGC
GCCGCTTCGCCAATGATAGCGAGCCAACTGGCGCGTTATCCGTTGTTGCTTGATGAACTGCTCGACCCCGGCACGCTTTA
TCAGCCGACGGCTACCGACGCTTACCGCGACGAATTACGCCAGTATTTGCTGCGCGTGCCGGAAGAGGACGAAGAACAAC
AACTGGAGGCATTACGCCAGTTTAAACAGGCACAGCTTTTGCGGATTGCGGCGGCGGATATTGCCGGTACGCTGCCGGTG
ATGAAAGTGAGCGATCACCTCACATGGCTGGCGGAGGCGATGATTGATGCTGTGGTGCAGCAGGCGTGGACGCAAATGGT
TGCGCGTTATGGTCAGCCAGCGCATCTGGACGAACGCCAGGGGCGGGGGTTTGCGGTCGTCGGTTATGGCAAGTTGGGCG
GATGGGAGCTGGGCTACAGTTCCGATCTGGATCTCATCTTCCTGCATGACTGTCCGATGGACGTCATGACCAACGGCGAA
CGCGAAATCGACGGGCGGCAGTTTTATCTGCGCCTGGCGCAGCGCATTATGCATCTGTTCAGTACGCGCACCTCCTCCGG
CATTTTGTATGAGGTGGATGCGCGTCTACGCCCCTCTGGCGCGGCTGGAATGCTGGTGACTTCAGCGGACGCGTTTGCCG
ATTATCAGCAGCATGAAGCCTGGACCTGGGAACATCAGGCGTTGGTACGCGCTCGCGTGGTATATGGCGACCCGCAGCTT
ACCTCACAGTTTGATGCGGTGCGCCGCACTATCATGACGACGGCGCGTGACGGTAAGACATTGCAGACTGAAGTGCGTGA
AATGCGCGAGAAAATGCGGGCGCATCTCGGCAATAAGCATCGCGATCGTTTTGATATTAAAGCTGATGAAGGCGGTATTA
CGGATATTGAGTTTATCGCGCAATATCTGGTACTGCGCTACGCTCATGAAAAACCTAAATTAACGCGCTGGTCTGATAAC
GTGCGCATCCTGGAGCTTCTGGCGCAAAACGGCATTATGGATGAACACGAAGCGCAGGCGCTGACGGTAGCCTACACCAC
ACTGCGTGATGAACTGCACCACCTGGCGTTGCAGGAGCTTCCCGGTCATGTGGCGCAGACATGTTTTAGCAAAGAGCGCG
CGCTGGTGCAGGCAAGCTGGCGGAAGTGGCTGGTAGCCGTTTGA

Upstream 100 bases:

>100_bases
GCCTGATGACGCTGCGCTTATCAGGCTTACGGTATGCGGACTTGTAGGCCGGATCAGGCGAAACGCCGCCATCCGGCATT
ATTTAAAGGATATCCCCTAA

Downstream 100 bases:

>100_bases
ATTATGCTATTATCGCGCGCAAATTTTGAATCTCTCAGGAGACAGGAATGAAAGTAAATCTGCCAGCGTTTGAACGTGCA
GGCGTCATGGTTGTGGGTGA

Product: bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase

Products: NA

Alternate protein names: Glutamine-synthetase adenylyltransferase; ATase; [Glutamate--ammonia-ligase] adenylyltransferase [H]

Number of amino acids: Translated: 947; Mature: 946

Protein sequence:

>947_residues
MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGV
CDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGM
GKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFA
ALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGA
GGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDL
NRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQ
VLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLC
AASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPV
MKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGE
REIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQL
TSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDN
VRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV

Sequences:

>Translated_947_residues
MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGV
CDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGM
GKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFA
ALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGA
GGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDL
NRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQ
VLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLC
AASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPV
MKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGE
REIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQL
TSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDN
VRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
>Mature_946_residues
TPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVC
DDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMG
KLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAA
LEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAG
GIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLN
RARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQV
LTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCA
ASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVM
KVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGER
EIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLT
SQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNV
RILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV

Specific function: Adenylation and deadenylation of glutamate--ammonia ligase [H]

COG id: COG1391

COG function: function code OT; Glutamine synthetase adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glnE family [H]

Homologues:

Organism=Escherichia coli, GI1789433, Length=945, Percent_Identity=88.2539682539683, Blast_Score=1684, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023057
- InterPro:   IPR005190
- InterPro:   IPR013546 [H]

Pfam domain/function: PF08335 GlnD_UR_UTase; PF03710 GlnE [H]

EC number: =2.7.7.42 [H]

Molecular weight: Translated: 107963; Mature: 107831

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESAS
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
PQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLS
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAW
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEC
PEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFA
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEHHH
ALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGE
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHH
LTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEHHHCCHHHHH
VLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
QYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGE
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHCCCC
REIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCC
WTWEHQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKH
CCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
RDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQA
CCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
LTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESAS
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
PQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIAWAQTLSLVDDETILQQLS
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAW
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEC
PEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFA
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCEEHHH
ALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGE
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHH
LTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEHHHCCHHHHH
VLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
QYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGE
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHCCCC
REIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCC
WTWEHQALVRARVVYGDPQLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKH
CCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
RDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQA
CCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHH
LTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA