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The map label for this gene is yqhD [H]

Identifier: 29143427

GI number: 29143427

Start: 3165314

End: 3166477

Strand: Direct

Name: yqhD [H]

Synonym: t3084

Alternate gene names: 29143427

Gene position: 3165314-3166477 (Clockwise)

Preceding gene: 29143425

Following gene: 29143428

Centisome position: 66.05

GC content: 55.41

Gene sequence:

>1164_bases
ATGAAAAATTTCAAATTACATACCCCTACCCGCATTCTGTTTGGTAAAGGCGCTATCGTCGATCTCCGCGATCAGATCCC
GCAGGACGCCCGCGTGCTGATTACCTATGGCGGCGGTAGCGTGAAAAAGACCGGCGTACTGGCGCAAGTTCAGGACGCGT
TAAAAGGACTGGATGTTCGGGAGTTTGGCGGTATTGAACCGAACCCGTCCTATGAAACGCTGATGAAGGCCGTGCAGCTT
GTGCGCGACGAAAGTATTACCTTCCTGCTGGCCGTTGGCGGCGGTTCCGTACTGGACGGCACCAAATTTATCGCCGCAGC
GGCGCAGTATACGGACGGCGTCGATCCGTGGCACATTCTGGAAACCGGCGGTACTGAGATTCGTAGCGCAATCCCGATGG
GGTCTGTGCTGACCCTACCGGCAACCGGCTCAGAATCGAACGCCGGCGCAGTCATTTCCCGTAAAACTACTGGCGACAAA
CAGGCCTTCCACTCCTCGTTCGTGCAACCGGTGTTTGCCGTACTGGACCCGGTCTACACCTATACATTGCCGCCGCGCCA
GGTTGCGAACGGCGTCGTGGATGCTTTCGTCCATACCGTTGAGCAGTACGTCACTTACCCCGTTAACGGCAAAATTCAGG
ATCGTTTCGCCGAAGGTATTTTACTCACACTGATCGAAGAAGGTCCCAAAGCGCTGCAAGAGCCTGAAAACTATGACGTC
CGCGCTAACGTGATGTGGGCCGCTACTCAGGCATTGAATGGCCTGATTGGCGCTGGTGTTCCGCAAGACTGGGCGACGCA
TATGCTGGGCCATGAGCTTACGGCGATGCACGGTCTCGATCATGCCCAGACGCTGGCTATCATTCTGCCTGCGCTATGGA
ACGAAAAACGAGACGTTAAACGCGCAAAACTCCTGCAATACGCTGAACGTGTATGGAATATCACCGACGGTTCCGACGAC
GAGCGTATTGATGCCGCCATTGCCGCCACCCGCCGTTTCTTCGAACAGATGGGCGTGCCTACCCACCTGTCCGATTACGG
TCTGGATGGCAGCACTATTCCGGCGCTACTGGCCAAACTTGAGGCGCATGGATGCACAAATTTAGGTGAAAATCAGGATA
TTACGCTGGATGTCAGCCGTCGGATTTATGAAGCGGCGCGCTAA

Upstream 100 bases:

>100_bases
GCAGAAATGTGCATTGAGAGACATCTCTCACAAGACCACAATGATGACCATCAGGCAGACAGCCGCCTGCCCTCTTTTTA
CCCACATAAGGGAATGAGCA

Downstream 100 bases:

>100_bases
GGTTTTTTCGCCTCTGACTTTCGTTTTTGGCCATTTCGTCCAGACTTAAGTCACTTAGTCTCGCCGGACCCGACTCCGGC
GAGCCAATTAAAAGAGGAAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKTGVLAQVQDALKGLDVREFGGIEPNPSYETLMKAVQL
VRDESITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR

Sequences:

>Translated_387_residues
MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKTGVLAQVQDALKGLDVREFGGIEPNPSYETLMKAVQL
VRDESITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR
>Mature_387_residues
MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKTGVLAQVQDALKGLDVREFGGIEPNPSYETLMKAVQL
VRDESITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDD
ERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=387, Percent_Identity=88.6304909560724, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=311, Percent_Identity=24.7588424437299, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789163, Length=382, Percent_Identity=25.3926701570681, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082107, Length=280, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787493, Length=382, Percent_Identity=25.130890052356, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=274, Percent_Identity=22.6277372262774, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321181, Length=359, Percent_Identity=25.0696378830084, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657991, Length=346, Percent_Identity=24.2774566473988, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42059; Mature: 42059

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKTGVLAQVQDALKGLDVR
CCCCCCCCCCEEEECCCCEEEHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
EFGGIEPNPSYETLMKAVQLVRDESITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHIL
HCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEE
ETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDKQAFHSSFVQPVFAVLDPVYT
ECCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHEEHHHHCHHHHCCCCCCCE
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVK
EEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
RAKLLQYAERVWNITDGSDDERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
EAHGCTNLGENQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEEHHHHHHHHCC
>Mature Secondary Structure
MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKTGVLAQVQDALKGLDVR
CCCCCCCCCCEEEECCCCEEEHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
EFGGIEPNPSYETLMKAVQLVRDESITFLLAVGGGSVLDGTKFIAAAAQYTDGVDPWHIL
HCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEE
ETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDKQAFHSSFVQPVFAVLDPVYT
ECCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAEGILLTLIEEGPKALQEPENYDV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHEEHHHHCHHHHCCCCCCCE
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIILPALWNEKRDVK
EEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
RAKLLQYAERVWNITDGSDDERIDAAIAATRRFFEQMGVPTHLSDYGLDGSTIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
EAHGCTNLGENQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]