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The map label for this gene is nadA [H]

Identifier: 29142537

GI number: 29142537

Start: 2185777

End: 2186820

Strand: Reverse

Name: nadA [H]

Synonym: t2122

Alternate gene names: 29142537

Gene position: 2186820-2185777 (Counterclockwise)

Preceding gene: 29142538

Following gene: 29142536

Centisome position: 45.64

GC content: 54.31

Gene sequence:

>1044_bases
ATGAGCGTAATGTTTGACTCACAAGCCGCAATCTACCCGTTCCCGCCGAAACCAACGCCGTTGAACGACGATGAAAAGCA
ATTTTATCGTGAGAAAATCAAGCGTTTGCTCAAAGAGCGCAATGCCGTCATGGTGGCGCACTACTACACCGATCCGGAAA
TTCAACAGTTAGCAGAAGAAACCGGCGGCTGTATTTCCGACTCGCTGGAAATGGCCCGTTTCGGCGCGAAGCACGCCGCA
TCCACGTTACTGGTAGCGGGCGTACGGTTTATGGGGGAAACCGCCAAAATCCTCAGCCCGGAAAAAAACGTTCTTATGCC
TACGCTGGCGGCGGAATGTTCGCTGGATTTAGGCTGCCCAATAGACGAATTTAGCGCTTTTTGTGATGCGCACCCTGACA
GAACCGTAGTGGTCTATGCTAACACCTCGGCTGCTGTTAAAGCGCGTGCGGACTGGGTTGTGACCTCCAGTATCGCCGTA
GAACTGATTGAGCATCTGGATAGTTTGGGGGAAAAAATTATCTGGGCGCCGGACAGACACCTGGGGAATTACGTGCAAAA
ACAGACCAGGGCCGATGTACTGTGTTGGCAAGGGGCGTGTATCGTGCATGACGAGTTTAAAACCCAGGCGTTGACCCGTT
TAAAAAAAATCTATCCCGATGCCGCTATTCTGGTTCACCCTGAATCGCCGCGGTCCATTGTCGAGATGGCCGATGCGGTG
GGCTCCACCAGTCAGCTTATTAAGGCGGCAAAAACGCTGCCGCACAGACAGCTTATCGTCGCGACCGATCGCGGCATCTT
CTACAAAATGCAGCAGGCGGTTCCGGATAAAGAGTTGCTTGAAGCACCAACGGCGGGCGAAGGGGCAACCTGTCGCAGCT
GCGCGCATTGTCCGTGGATGGCGATGAACGGCCTGAAAGCCATTGCTGAAGGGCTGGAGCAGGGAGGCGCGGCGCATGAA
ATACAGGTTGATGCGGCGCTACGCGAGAGCGCATTACTTCCCCTCAACCGGATGCTGGATTTTGCGGCTACACTTCGGGT
GTAA

Upstream 100 bases:

>100_bases
TCAGCTATCTTGTTTAGCATATAAAACAAATTGACCGATTGTGGCGTTTATTACGCTTTCATTCGGTTGTTTCGTTAAGT
CAGTAAAACGAGAAGCCACG

Downstream 100 bases:

>100_bases
AGACGGAAATCTTTGGGGGAGAGAATGGATTTTTTTAGTACGCACAACATACTGATTCATATTCCGATTGGCGCTGGCGG
GTACGATCTCTCATGGATCG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAA
STLLVAGVRFMGETAKILSPEKNVLMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIEHLDSLGEKIIWAPDRHLGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIYPDAAILVHPESPRSIVEMADAV
GSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHE
IQVDAALRESALLPLNRMLDFAATLRV

Sequences:

>Translated_347_residues
MSVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAA
STLLVAGVRFMGETAKILSPEKNVLMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIEHLDSLGEKIIWAPDRHLGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIYPDAAILVHPESPRSIVEMADAV
GSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHE
IQVDAALRESALLPLNRMLDFAATLRV
>Mature_346_residues
SVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAAS
TLLVAGVRFMGETAKILSPEKNVLMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVE
LIEHLDSLGEKIIWAPDRHLGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIYPDAAILVHPESPRSIVEMADAVG
STSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEI
QVDAALRESALLPLNRMLDFAATLRV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=88.4393063583815, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38074; Mature: 37943

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CCEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKNVLMPTLAAECSLDLGCP
HCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECHHHHHHCCCCCCCC
IDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIYPDAAILVHPESPRSIVEMADAV
HHHHHHHHHHHCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
GSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLKAIAEGLEQGGAAHEIQVDAALRESALLPLNRMLDFAATLRV
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKNVLMPTLAAECSLDLGCP
HCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECHHHHHHCCCCCCCC
IDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIYPDAAILVHPESPRSIVEMADAV
HHHHHHHHHHHCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
GSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLKAIAEGLEQGGAAHEIQVDAALRESALLPLNRMLDFAATLRV
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA