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The map label for this gene is pnuC [H]

Identifier: 29142536

GI number: 29142536

Start: 2185033

End: 2185752

Strand: Reverse

Name: pnuC [H]

Synonym: t2121

Alternate gene names: 29142536

Gene position: 2185752-2185033 (Counterclockwise)

Preceding gene: 29142537

Following gene: 29142533

Centisome position: 45.61

GC content: 50.0

Gene sequence:

>720_bases
ATGGATTTTTTTAGTACGCACAACATACTGATTCATATTCCGATTGGCGCTGGCGGGTACGATCTCTCATGGATCGAAGC
GGTAGGAACCATCGCCGGCCTGCTCTGTATTTGGCTTGCCAGTCTGGAGAATATCAGCAACTACTTTTTTGGACTGGTTA
ACGTCACCCTGTTTGCGATTATTTTCTTTCAGATCCAGCTTTATGCCAGCCTGTTGCTGCAACTCTTTTTCTTTGCCGCC
AATATTTATGGCTGGTATGCGTGGTCGCGGCAAACAAAGGATAATGAGGCCGAGCTTAAAATACGCTGGCTGCCGTTGCC
AAAAGCAATGGCATGGCTGGCGATATGTGTGATAGCTATCGGTTTGATGACGCGATATATCGATCCCGTATTCGCCGTCC
TGACGCGCGTGGCCGTCGCCATTATGCAGATGCTGGGGTTACAGGTGACAATGCCTGTACTGCAACCGGACGCTTTCCCG
TTCTGGGACTCTTGCATGATGGTGCTGTCTATCGTGGCGATGATTTTGATGACACGCAAATATGTCGAAAACTGGCTCCT
GTGGGTGATAATCAACGTAATCAGTGTGGTGATTTTTGCTTTGCAGGGCGTCTATGCGATGTCGCTGGAATATCTGATCC
TGACATTTATCGCCGTGAACGGTAGTCGCCTGTGGATAAACAGCGCGCGGGAGCGAGGATCGCGCGCGCTTTCCCGTTAA

Upstream 100 bases:

>100_bases
TGATGCGGCGCTACGCGAGAGCGCATTACTTCCCCTCAACCGGATGCTGGATTTTGCGGCTACACTTCGGGTGTAAAGAC
GGAAATCTTTGGGGGAGAGA

Downstream 100 bases:

>100_bases
TGGTGATGAACATGCCCGGATGGCGTCTGATTCAGGTGACAGTCCGGGCCGTGACACATTTGATACTCCATTTGAATCGT
AGCGTGCGCAATATGGTATT

Product: pnuC protein

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLENISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNEAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR

Sequences:

>Translated_239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLENISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNEAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
>Mature_239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLENISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNEAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=239, Percent_Identity=88.7029288702929, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27178; Mature: 27178

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLENISNYFFGLVNVTLFAI
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNEAELKIRWLPLPKAMAWLAICVIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
GLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFPFWDSCMMVLSIVAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLENISNYFFGLVNVTLFAI
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNEAELKIRWLPLPKAMAWLAICVIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
GLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFPFWDSCMMVLSIVAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]