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The map label for this gene is asnC [H]

Identifier: 29142358

GI number: 29142358

Start: 1977682

End: 1979082

Strand: Direct

Name: asnC [H]

Synonym: t1934

Alternate gene names: 29142358

Gene position: 1977682-1979082 (Clockwise)

Preceding gene: 29142357

Following gene: 29142359

Centisome position: 41.27

GC content: 55.1

Gene sequence:

>1401_bases
ATGAGCGTTGTGCCTGTAGCCGACGTACTCCAGGGCCGCGTAGCCGTTGACCAAGAAGTCACCGTGCGCGGATGGGTGCG
TACCCGCCGAGATTCAAAAGCTGGCATCTCCTTCCTCGCCGTTTATGACGGCTCCTGCTTTGATCCTGTACAGGCTGTCA
TTAATAATTCTCTGCCCAATTATAATGAAGAAGTATTACACCTGACGACAGGCTGCTCCGTGGTAGTAACAGGTAAGGTT
GTCGCGTCGCCGGGACAGGGGCAAAGTTTCGAAATCCAGGCCACGAAAGTAGAGGTCGCAGGCTGGGTGGAAGATCCGGA
TACCTACCCGATGGCGGCAAAACGCCATAGCATTGAGTATCTGCGTGAAGTCGCGCATCTGCGCCCGCGCACCAACCTGA
TTGGCGCGGTAGCGCGCGTCCGCCATACTCTGGCGCAGGCGCTGCATCGCTTCTTCGATGAGCAGGGTTTCTTTTGGGTC
TCTACCCCGCTGATTACCGCTTCCGATACCGAAGGCGCTGGCGAAATGTTCCGCGTCTCAACGTTGGATCTGGAAAACCT
GCCGCGTAACGACCAGGGCAGAGTAGATTTTGACAAAGACTTTTTTGGCAAAGAATCATTCCTGACCGTCTCCGGCCAGC
TCAATGGTGAAACCTATGCCTGTGCGCTGTCCAAAATCTATACTTTTGGGCCGACCTTCCGCGCGGAAAATTCCAACACC
AGCCGCCACCTGGCGGAGTTCTGGATGCTGGAGCCGGAAGTGGCGTTCGCCGATCTGGAAGACAACGCCCGTCTGGCGGA
AGCCATGCTGAAATATGTCTTCAAGGCGGTTCTGGAAGAGCGTGCGGATGACATGAAGTTCTTTGCCGAACGCGTGGATA
AAGACGCTATCGCTCGTCTGGAGCGTTTTGTCTCCACCGACTTTGCTCAGGTGGATTACACCGATGCGGTCGCCATTCTG
GAACGCTGTGGTAAGACATTTGAAAACCCGGTGTTCTGGGGCGTCGACCTTTCTTCCGAACACGAACGTTATCTGGCGGA
AGAGCATTTCAAAGCGCCGGTAGTGGTGAAAAACTATCCGAAAGAAATTAAAGCGTTTTACATGCGCCTTAACGAAGATG
GCAAAACCGTGGCGGCCATGGATGTGCTGGCGCCGGGAATCGGCGAAATCATCGGTGGTTCCCAGCGTGAAGAGCGTCTG
GATGTGCTGGATGCCCGTATGGCCGAAATGGGGCTGAATAAAGAGGATTACTGGTGGTATCGCGACTTGCGTCGCTACGG
TACTGTACCGCATTCCGGCTTTGGCCTGGGCTTTGAACGCCTTATCGCTTACGTCACGGGTGTGCAAAACGTGCGCGATG
TTATTCCGTTCCCACGGACCCCACGCAACGCCAGCTTCTGA

Upstream 100 bases:

>100_bases
TTTCTGCTTGTCTGATTGCAGATGCCAGGTAACATAGGAATACCCCCATTTCGGGTGGACAAGTGTTTATTTTTTCCGAC
TATTAACTAGAGAGAATATT

Downstream 100 bases:

>100_bases
TTTTTACGTCACACTCAAGGCCAGCTATGCTGGCCTTTTTTTTCGCCTGAATGTCAGTTTTATTATCAATAAGTAAATAA
ATTTAATTACAACCCTCTGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKV
VASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKAVLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAIL
ERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF

Sequences:

>Translated_466_residues
MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKV
VASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKAVLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAIL
ERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
>Mature_465_residues
SVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKVV
ASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWVS
TPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKAVLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAILE
RCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=41.9006479481641, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI4758762, Length=448, Percent_Identity=28.125, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI45439306, Length=349, Percent_Identity=28.6532951289398, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=94.6351931330472, Blast_Score=920, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=473, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788173, Length=105, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=472, Percent_Identity=29.0254237288136, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17556372, Length=427, Percent_Identity=29.9765807962529, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=347, Percent_Identity=27.3775216138329, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=468, Percent_Identity=35.8974358974359, Blast_Score=280, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6321807, Length=457, Percent_Identity=30.6345733041575, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=487, Percent_Identity=25.6673511293634, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.3448275862069, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19921528, Length=467, Percent_Identity=28.6937901498929, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17136276, Length=490, Percent_Identity=27.1428571428571, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52538; Mature: 52407

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPN
CCCCCHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEECEEEECCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKAVLEERADDMKFFAERVDKDAIARL
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ERFVSTDFAQVDYTDAVAILERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
KEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPN
CCCCHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEECEEEECCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHHCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKAVLEERADDMKFFAERVDKDAIARL
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ERFVSTDFAQVDYTDAVAILERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
KEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA