Click here to switch to the map view.

The map label for this gene is pncB [H]

Identifier: 29142355

GI number: 29142355

Start: 1972525

End: 1973727

Strand: Direct

Name: pncB [H]

Synonym: t1930

Alternate gene names: 29142355

Gene position: 1972525-1973727 (Clockwise)

Preceding gene: 29142354

Following gene: 29142357

Centisome position: 41.16

GC content: 54.11

Gene sequence:

>1203_bases
ATGACACAATTCGCTTCTCCTGTTCTGCACTCGTTGCTGGATACAGATGCTTATAAGTTGCATATGCAGCAAGCCGTTTT
TCACCACTACTATGATGTGCAGGTAGCGGCTGAGTTTCGTTGCCGTGGCGACGACCTGCTGGGTATTTATGCCGATGCTA
TTCGCGAGCAGGTGGACGCGATGCAGCACCTGCGCCTCCAGGAGGACGAGTTCCAGTGGCTCTCCGGCCTGCCCTTTTTT
AAACCGGATTATCTGAACTGGTTACGCGAGTTTCGCTATAACCCAGCTCAAGTCTGTGTCACCAACGATAACGGCAAGCT
GAATATTCGCTTAACCGGCTCGTGGCGTGAAGTCATTATGTGGGAAGTGCCGCTGCTGGCCGTGATCAGTGAGCTGGTTC
ATCACTACCGCTCGCCAAACGCGGGCGTTGATCAGGCGCTCGACGCGCTGGAAAGTAAGCTGGTTGATTTCACTGCGTTA
ACCGCCAATCTCGATATGTCCCGCTTCCACCTGATGGACTTCGGCACCCGCCGCCGTTTCTCTCGTGAAGTGCAGCAGGC
GATAGTTAAACGTCTCCAGCAGGAGTCATGGTTCGTCGGCACCAGCAACTATGATCTCGCGCGTCGCCTGGCGCTGACGC
CGATGGGCACTCAGGCGCACGAATGGTTCCAGGCGCATCAACAAATCAATCCGGACCTGGCGACCAGTCAGCGTGCCGCG
TTGGCCGCCTGGCTTAACGAATATCCGGACCAGCTTGGTATCGCATTGACAGATTGCATTACAATGGATGCGTTTTTACG
CGATTTCGGCATTGAATTCGCCAGCCGTTATCAGGGGTTACGCCACGACTCAGGAGACCCTGTCGCATGGGGCGAAAAGG
CGATTGCCCATTATGAAAAGCTGGGGATTGATCCGCTGACAAAAACGCTGGTCTTTTCAGATAACCTTGATCTGCCAAAG
GCGGTCGAGCTCTATCGCCATTTCGCCTCTCGCGTGCAGTTAAGCTTCGGCATCGGTACCCGACTGACCTGCGATATCCC
TCAGGTAAAACCGCTCAATATCGTGATTAAGCTCGTGGAATGTAACGGAAAGCCGGTGGCTAAACTTTCCGACAGCCCCG
GTAAAACGATCTGTCATGATAAAGCGTTTGTGCGCGCGCTGCGTAAAGCGTTCGATCTCCCGCAGGTGCGTAAAGCAAGT
TAA

Upstream 100 bases:

>100_bases
GATCGGGGTTCAATAAATCGCTAAACAAGGTATACTCCAGCGGTTTTCTTAGTTGTTTATTGTACTAAACACTCCCGTGA
GAGGACGCAACAGCGCACCT

Downstream 100 bases:

>100_bases
CCATGCCTGTGCGAAGCGCCCGGAAAGTGGGCGCTTTGTTACTCTTCTGACCATCTTACCTGTTCTGGCCGCGATGGTGA
CTATTCTTCCCCTTCACTCT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFF
KPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGSWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQINPDLATSQRAA
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPK
AVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS

Sequences:

>Translated_400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFF
KPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGSWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQINPDLATSQRAA
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPK
AVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
>Mature_399_residues
TQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFFK
PDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGSWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALT
ANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQINPDLATSQRAAL
AAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPKA
VELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=400, Percent_Identity=90.75, Blast_Score=765, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324783, Length=419, Percent_Identity=34.3675417661098, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45694; Mature: 45562

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHH
MQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGSWREVIM
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTANLDMSRFHLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQINPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEK
HHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCHHHHHEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHH
MQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGSWREVIM
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTANLDMSRFHLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
SREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQINPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEK
HHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCHHHHHEEEECCCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA