Click here to switch to the map view.

The map label for this gene is int [H]

Identifier: 29142354

GI number: 29142354

Start: 1970990

End: 1972330

Strand: Direct

Name: int [H]

Synonym: t1929

Alternate gene names: 29142354

Gene position: 1970990-1972330 (Clockwise)

Preceding gene: 29142353

Following gene: 29142355

Centisome position: 41.13

GC content: 48.84

Gene sequence:

>1341_bases
ATGAAAAGCAGTACACTCGTCAATGCTCCTGGACGTCAGGAGGGATTAATGGCTAATGCATCATACCCGACAGGCGTCGA
AAACCACGGCGGTTCGCTCCGCATCTGGTTTCTGTATAAAGGTAAACGTGTCAGGGAAAACCTTGGTATCCCTGACACTG
CAAAAAATCGCAAGATAGCTGGCGAACTGCGTTCTTCGGTTTGTTTTGCGATAAGGATGGGGAATTTTAACTATGTGGAA
AAATTCCCAAACTCAACGAACCTTGCCCGGTTCGGTCAGGATAGAAAGGAAATTACTGTGCTGGAGCTTACCGAAAGATG
GTCCGAGCTGAAGAGAATGGAGATCAGCTCTAATACCATGAGTAGGTACGAATCTATCATAAAAAACATGCTTCCACTCA
TCGGCGAAAACAAAATGGTTTCTGCGGTGACTACTGAGGATTTGCTGTATGTCAGGAAGGAGTTGCTGACGGGCTTTCAG
GTAATGAAGAAGGATCACCGGACTCAGGTTAAAGGCCGGAAATCGTCCACAGTGAATAATTACATGATGCTGATGGCCGA
GATCTTCCAGTTTGGAACAGATAACGGCTATGCAAAGGAAAACCCGTTTAGCGGAATTAACCGTCTCAAGAAAGCGAAAG
GGGAACCAGATCCACTCACGACAGACGAGTTCATCAGGTTTATCCAGGCATGCGGCCACCAGCAGATGAGAAATCTCTGG
TCACTGGCAGTCTATACCGGAATGAGGCATGGGGAGTTGTGCGGTCTGGCCTGGGAAGATATCGATCTGCATGCCGGGAC
GATCATTGTGAAGCGCAACCTTACCCAGACGGATGAGTTCACCCTGCCAAAAACCGACGCAGGTACTGACAGGGTGATAT
ATCTCATTCAACCAGCTATTGATGCCCTGAGGAATCAGGCCCAGTTGACACGCCTTGGCCGGCAGTTTGAGGTTGAAGTG
AAGTTGCGGGAATATGGACAATCTGTCATTCAGCCCTGCACGTTCGTATTCAGCCCTCAATGCGTCAAACGTGGACCTCG
CACAGGATATCACTACGCGGTTAATTCCATTAATAAAATTTGGGCCCCGATAATCAAGCGTGCCGGCATTCGTTACCGTA
ACGCGTATCAGTCACGACATACCTATGCATGCTGGTCATTATCAGCTGGTGCTAACCCAAACTTTATAGCAACGCAGATG
GGGCATACCGATGCACAGATGGTTTACAAGGTGTATGGAAAGTGGATGTCAGAGAAGAGCGCAGAACAGGTTTCTCTGCT
CAACCAGGCACTTTCCCGCTATGCCCCATCACTGCCCCAAAGCATGGTAGCAGCGCAGTAG

Upstream 100 bases:

>100_bases
ACGGAAATCCGAAGCCTTCGAGCGAATGCATATACAACAGAGAAGCCGTTGATCAGTGGATCGAGGCGCAGAAAAAAAAT
CAACCAGGTGCGAAGACAAC

Downstream 100 bases:

>100_bases
AAATCCTTAAATTCAAGGGGTTAGCAGTCGCATCGCTACATTTTTATAACATGGGGCACGAAATGCGCTCGACCCTAAAG
ACAGCTTATGGTGTGATCGG

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKSSTLVNAPGRQEGLMANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIAGELRSSVCFAIRMGNFNYVE
KFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSNTMSRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQ
VMKKDHRTQVKGRKSSTVNNYMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQQMRNLW
SLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRVIYLIQPAIDALRNQAQLTRLGRQFEVEV
KLREYGQSVIQPCTFVFSPQCVKRGPRTGYHYAVNSINKIWAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQM
GHTDAQMVYKVYGKWMSEKSAEQVSLLNQALSRYAPSLPQSMVAAQ

Sequences:

>Translated_446_residues
MKSSTLVNAPGRQEGLMANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIAGELRSSVCFAIRMGNFNYVE
KFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSNTMSRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQ
VMKKDHRTQVKGRKSSTVNNYMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQQMRNLW
SLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRVIYLIQPAIDALRNQAQLTRLGRQFEVEV
KLREYGQSVIQPCTFVFSPQCVKRGPRTGYHYAVNSINKIWAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQM
GHTDAQMVYKVYGKWMSEKSAEQVSLLNQALSRYAPSLPQSMVAAQ
>Mature_446_residues
MKSSTLVNAPGRQEGLMANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIAGELRSSVCFAIRMGNFNYVE
KFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSNTMSRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQ
VMKKDHRTQVKGRKSSTVNNYMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQQMRNLW
SLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRVIYLIQPAIDALRNQAQLTRLGRQFEVEV
KLREYGQSVIQPCTFVFSPQCVKRGPRTGYHYAVNSINKIWAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQM
GHTDAQMVYKVYGKWMSEKSAEQVSLLNQALSRYAPSLPQSMVAAQ

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787607, Length=411, Percent_Identity=43.30900243309, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR022000
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF12167 DUF3596; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 50645; Mature: 50645

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSTLVNAPGRQEGLMANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIA
CCCCCEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHH
GELRSSVCFAIRMGNFNYVEKFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSNTM
HHHHHCEEEEEEECCCHHHHHCCCCCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHCHHHH
SRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQVMKKDHRTQVKGRKSSTVNN
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQQMRNLW
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
SLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRVIYLIQPAI
HHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHH
DALRNQAQLTRLGRQFEVEVKLREYGQSVIQPCTFVFSPQCVKRGPRTGYHYAVNSINKI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
WAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQMGHTDAQMVYKVYGKWMSEKS
HHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AEQVSLLNQALSRYAPSLPQSMVAAQ
HHHHHHHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MKSSTLVNAPGRQEGLMANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIA
CCCCCEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHH
GELRSSVCFAIRMGNFNYVEKFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSNTM
HHHHHCEEEEEEECCCHHHHHCCCCCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHCHHHH
SRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQVMKKDHRTQVKGRKSSTVNN
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQQMRNLW
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
SLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRVIYLIQPAI
HHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHH
DALRNQAQLTRLGRQFEVEVKLREYGQSVIQPCTFVFSPQCVKRGPRTGYHYAVNSINKI
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
WAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQMGHTDAQMVYKVYGKWMSEKS
HHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AEQVSLLNQALSRYAPSLPQSMVAAQ
HHHHHHHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]