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The map label for this gene is adrB [H]

Identifier: 29141525

GI number: 29141525

Start: 1133049

End: 1134650

Strand: Reverse

Name: adrB [H]

Synonym: t1050

Alternate gene names: 29141525

Gene position: 1134650-1133049 (Counterclockwise)

Preceding gene: 29141526

Following gene: 29141523

Centisome position: 23.68

GC content: 53.25

Gene sequence:

>1602_bases
ATGCAAACAGCACAACGGATCATCAATCATTATCGCCGTAATCGTTTCATTGTTTGCACGATTTGTGCACTGGTCACGCT
CATTCTTACGCTGAACATCCGATTTATTTCGGAGCGGAACTTAAATCACCATCGCACGGTTGCATTCGCGAATCATGCCG
TTGATGCGCTGGATAATGTGCTGCATCCTCTCCTGGTCGGACGAAACATACTGCTACCCTTACTTGAGCTTCCGTGCGCG
ACCGCGCATCTGCCGTTGCGTAAGCAAGCCGCCCGCCTGCAAACCATTCGTTCTATCGGGCTGGTAAAAGAGGGAATTCT
CTACTGCTCAAGCATTTTTGGCGCCCGTAATACTCCCATACGCCAGCTTCAGCCCGATCTTCCCGCAGCTGGCGATCTGC
TGCTACTTTCCACGGACCAATCGTTACTCAAGGGAAGCCCGATCCTCATTCAGTGGTATCCCGCCTCTGCCGATGGACAG
GATGGCGTGATGGAAATTGTGAATATTGACTTGCTGGCGACTATGCTACTTGAGCCGCAGCAGCCGCAAATTACCAGCGC
CAGCCTGACGGTCGGCAAACGGCACCTGTTATATGGTCGGGGCGTGGTCGATACTCTTCCGGAATTAAAAAAAGATGAAG
AGCGTTACCAGCTTTCATCGCGGCATTTCCCTTTTACTATCAGCGTCAGCGGGCCGTCGGCAGGCGTACTGGCGTTCAAA
CATCTCCCGACGCAGTTACCGCTGGCCGTATTGCTTAGCCTGTTGATCGGTTATATCGCCTGGCTGGCAACCGCCAGCAG
AATGAGCTTTTCCTGGGAAATTAATCTGGCCCTTGCCGAACGGGAGTTTGAGCTATTTTGTCAGCCGTTGCTTAATGCCC
GCACGCAGCAGTGTACCGGCGTTGAGATCCTGTTACGCTGGAATAACCCGCGCCAGGGCTGGATCTCACCGGATGTTTTT
ATTCCTATCACCGAGGAGCATAACCTGATAGCGCCGCTGACCCGCTATGTGATTGCGGAAACCATTCGGCAGCGGCACTA
CTTCCCCATCAACCATCAGTTTCATATCGGCATCAATGTGGCGGCAAGCCATTTCCGACACGGCGTGCTTCTCAAGGATC
TTAATCAGTACTGGTTTAGTGCGGAACCTGTTCAGCAACTGGTGCTGGAGCTCACGGAACGCGACGCGTTGCTTGACGTT
GATTACCGCCTGATGCGCGAGCTGCATCGTAAAGGCGTGAAGTTAGCCATCGATGATTTTGGCACAGGAAACAGCTCGCT
CTCCTGGCTGGAAAAACTGCGTCCGGATATTTTGAAAATCGATAAATTCTTCACCGCCGTCATCGGTACCGATGCGGTCA
ATTCAACGGTGACCGATATTATTATCGCGCTGGGGCAAAGACTGAATATTGAACTGGTTGCGGAAGGGGTCGAAAACCAG
ACGCAGGCACAGCATTTGCGCCAGCATGGCGTGCAAATGTTACAGGGCTATCTCTATGCGAAGCCGATGCCCATTAGCGA
ATTTCCACAGTGGCTGGCGGGCAGCGCGCCGCCGCCCGCCCGGCATAACGGACAGATTATGTCCGCGATGCCGCATCTAT
AG

Upstream 100 bases:

>100_bases
GGGCGAAATTTTTATCTCTTCCTCGTCGACTCCACGTTTCCCCACTACACTTGCTGTGTCGCGGTTGGCTTTTGTCGCCA
ACGCTTATTGGGCGGCCCGC

Downstream 100 bases:

>100_bases
ACTTGATTCCTGCGTGTGACGTTATTCCTCTTCGTCGTGGGCAGGCTGTTCTTTAACAATTCGAACCAGATCGACACGGT
AGTCGTTGGCCTCGACAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHHRTVAFANHAVDALDNVLHPLLVGRNILLPLLELPCA
TAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPIRQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQ
DGVMEIVNIDLLATMLLEPQQPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTGVEILLRWNNPRQGWISPDVF
IPITEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINVAASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDV
DYRLMRELHRKGVKLAIDDFGTGNSSLSWLEKLRPDILKIDKFFTAVIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL

Sequences:

>Translated_533_residues
MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHHRTVAFANHAVDALDNVLHPLLVGRNILLPLLELPCA
TAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPIRQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQ
DGVMEIVNIDLLATMLLEPQQPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTGVEILLRWNNPRQGWISPDVF
IPITEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINVAASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDV
DYRLMRELHRKGVKLAIDDFGTGNSSLSWLEKLRPDILKIDKFFTAVIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL
>Mature_533_residues
MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHHRTVAFANHAVDALDNVLHPLLVGRNILLPLLELPCA
TAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPIRQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQ
DGVMEIVNIDLLATMLLEPQQPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTGVEILLRWNNPRQGWISPDVF
IPITEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINVAASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDV
DYRLMRELHRKGVKLAIDDFGTGNSSLSWLEKLRPDILKIDKFFTAVIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL

Specific function: May serve as a negative regulator of cellulose synthesis (as has been suggested for S.typhimurium); over-expression inhibits cell aggregation in strains able to produce adhesive curli fimbriae. Cyclic-di-GMP is a second messenger which controls cell surfa

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081980, Length=531, Percent_Identity=74.7645951035782, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1788502, Length=522, Percent_Identity=28.735632183908, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081845, Length=518, Percent_Identity=28.5714285714286, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=38.4615384615385, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=36.5145228215768, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081921, Length=261, Percent_Identity=33.7164750957854, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87081743, Length=272, Percent_Identity=34.1911764705882, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787541, Length=243, Percent_Identity=32.0987654320988, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI226510982, Length=256, Percent_Identity=30.078125, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082096, Length=247, Percent_Identity=28.7449392712551, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788849, Length=237, Percent_Identity=32.0675105485232, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 59967; Mature: 59967

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHHRTVAFANHAVDALDNV
CCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEHHHHHHHHHHH
LHPLLVGRNILLPLLELPCATAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPI
HHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQDGVMEIVNIDLLATMLLEPQ
HHCCCCCCCCCCEEEEECCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
QPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
CCCCCCHHEECCCHHEEECCCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEHHH
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTG
HCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCC
VEILLRWNNPRQGWISPDVFIPITEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINV
EEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEH
AASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDVDYRLMRELHRKGVKLAIDDF
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHCCCEEEEECC
GTGNSSLSWLEKLRPDILKIDKFFTAVIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
CCCCCHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHHRTVAFANHAVDALDNV
CCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEHHHHHHHHHHH
LHPLLVGRNILLPLLELPCATAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPI
HHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQDGVMEIVNIDLLATMLLEPQ
HHCCCCCCCCCCEEEEECCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
QPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
CCCCCCHHEECCCHHEEECCCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEHHH
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTG
HCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCC
VEILLRWNNPRQGWISPDVFIPITEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINV
EEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEH
AASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDVDYRLMRELHRKGVKLAIDDF
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHCCCEEEEECC
GTGNSSLSWLEKLRPDILKIDKFFTAVIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
CCCCCHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]