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The map label for this gene is xapB [H]

Identifier: 29140963

GI number: 29140963

Start: 509300

End: 510556

Strand: Direct

Name: xapB [H]

Synonym: t0436

Alternate gene names: 29140963

Gene position: 509300-510556 (Clockwise)

Preceding gene: 29140962

Following gene: 29140964

Centisome position: 10.63

GC content: 48.93

Gene sequence:

>1257_bases
ATGGGTATTACGTCCCGCTTAAAAGTCATGTCGTTCTTGCAATATTTTATCTGGGGGAGCTGGCTGGTTACCCTGGGCTC
TTACATGATCAACACTCTGGATTTTACCGGCGCGAATGTCGGTATGGTCTACAGCTCAAAAGGACTGGCAGCGATTATCA
TGCCGGGCATTATGGGGATCATTGCTGATAAATGGCTGCGCGCTGAGCGAGCCTATATGCTTTGCCATCTGGTTTGCGCG
GGGGCGTTATTGTACGCCACCACCGTTACCGATCCCCAGACGATGTTCTGGGTGATGTTGGTTAATGCGATGGCGTATAT
GCCAACGATTGCATTATCCAATAGCGTTTCGTACTCCTGTCTGGCGAAAGCAGGTCAGGATCCGGTAACGTCATTTCCGC
CCGTGCGCGTTTTCGGCACAATAGGTTTTATTGTTGCGATGTGGACGGTGAGCCTGATGGGGCTGGAACTGAGCAGTGCG
CAATTATACATCGCTTCTGGCGCATCGTTATTGCTGGCCCTGTATGCGCTGACGTTACCGAAAATTCCGGTAGCCGAGAA
GAAGGCGAACACCACGCTTGTCAGTAAGCTCGGACTGGATGCTTTTGTTCTGTTTAAAAATCCACGCATGGCAATCTTCT
TTTTGTTTGCGATGATGTTGGGGGCGGTGCTGCAAATTACCAATGTCTTCGGTAATCCGTTCCTGCATGATTTTGCCCGT
AATCCTGAGTTTGCCGATAGTTTTGTGGTGAAGTATCCCTCTATCTTGCTTTCAGTTTCGCAGATGGCGGAAGTGGGCTT
TATCCTCACCATTCCGTTCTTCCTTAAACGCTTTGGTATTAAAACGGTAATGCTGATGAGCATGCTGGCGTGGACGCTGC
GTTTCGGCTTCTTTGCCTTTGGCGATCCATCCCCGTTTGGCTTTGTGCTATTGCTGCTGTCGATGATTGTTTATGGCTGC
GCATTTGATTTCTTCAACATCTCAGGGTCAGTATTTGTAGAGCAGGAGGTGGACTCAAGTATTCGCGCCAGCGCGCAGGG
GCTGTTTATGACCATGGTTAACGGCGTGGGGGCGTGGATTGGGTCTCTTTTAAGCGGTATGGCCGTGGATTATTTTTCTA
TTGATGGCGTAAAAGATTGGCAAACCATCTGGCTGGTTTTTGCCGCCTACGCTCTGGCATTGGCCGTTATTTTTGCATTG
TTCTTTAAATATCAGCACCATCCAGAAAAACTGTCGACCAAATCATTAGCACATTAA

Upstream 100 bases:

>100_bases
GAACTTTATCAATCTGATTTGCGGCTTTTTACGTAAGCTGGCCTAAACACAATGACTACGGCCCCGTATTGGGGCTTTAT
CTCACGGCAAGGAATAAAAA

Downstream 100 bases:

>100_bases
TTTTATTTGACTGGCGAGAGGATGTTCGCCAGTCCATTTTTATGAACAAGGACACAGTATGAAAGAAATTATTCTCTCCT
CCGGTATTGGATTTGGTATT

Product: xanthosine permease

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCA
GALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
QLYIASGASLLLALYALTLPKIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGC
AFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFAL
FFKYQHHPEKLSTKSLAH

Sequences:

>Translated_418_residues
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCA
GALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
QLYIASGASLLLALYALTLPKIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
NPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGC
AFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFAL
FFKYQHHPEKLSTKSLAH
>Mature_417_residues
GITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCAG
ALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQ
LYIASGASLLLALYALTLPKIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARN
PEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGCA
FDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALF
FKYQHHPEKLSTKSLAH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=88.5167464114833, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=58.133971291866, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1788415, Length=423, Percent_Identity=29.5508274231678, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45996; Mature: 45865

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
IADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQLYIASGASLLLALYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHCC
KIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPFGFVLLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALFFKYQHHPEKLSTKSLAH
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCC
>Mature Secondary Structure 
GITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVYSSKGLAAIIMPGIMGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
IADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVNAMAYMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSAQLYIASGASLLLALYALTLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHCC
KIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFAR
CCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMLAWTLRFGFFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPSPFGFVLLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFSIDGVKDWQTIWLVFAAYALALAVIFALFFKYQHHPEKLSTKSLAH
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]