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The map label for this gene is mviN [H]

Identifier: 28572950

GI number: 28572950

Start: 916433

End: 917989

Strand: Direct

Name: mviN [H]

Synonym: TW809

Alternate gene names: 28572950

Gene position: 916433-917989 (Clockwise)

Preceding gene: 28572948

Following gene: 28572951

Centisome position: 98.97

GC content: 48.36

Gene sequence:

>1557_bases
ATGGATACCCGACGCGCAAGTGCAGTAATGGCCCTCGGAACACTGGTATCGAGGGTGATTGGGTTTCTTGGCATGATATT
GCTCACCTATGCTACAGGATCTATCGGAAGCGGGGCAAACGCATTTGCCGTTGCAAATTATTTACCAAACATGATCTACG
CCATTGTTGCCGGAGGAACGGTTAATGCGGTGCTGATTCCTCAAGTGGTTCGGTTCTCTGCATCGGGAAATGAGAGGTAT
ATAAACAAAATCACAACTCTGGCTATTGTGCTATTCGCCTTTATAACCCTAGTAGCCGCCTTCTTGTCGCCAACCCTCGT
AAAAATCACTGCTGGGGCGGGGTTCGATAAGCAAACCACCGCTGTGGCCATATCATTCGCTTATTGGTGTGTACCGCAGA
TCTTTTTCTACGCTATCTATAGCGTCCTTGGAGAGGTGCTCAATGCTCGCAAAGTATACGGGCCATTTACCTGGACTCCA
GCTATAAACAATATTGTCTTTATCTCCGGTATTTTGTTGTTCATCCTTGTATTCGGCGCTGACCCCGAGGGCTCTAGGGG
TGCGTGGCCCCCGTTTGCCATTGCAATCCTGGGGGGATCTGCAACTCTTGGCATAGCATGTCAAGCTCTTTTTCTCTTGA
TTTTCTGGAAATCCGCAGGACTCCGGTTCAAGCCGGATTTTAACTGGCGCGGTATACAGATAACAAATCTCGGAAAAATA
TTCTCCTGGACATTTTTCATGGTGGTGATAACTACAATAGCGGGCCTGGTGGAAACGAATATATCAACCCTTGCAGGCAA
TCACAACGCATCTGTTGCGGTCATGCAAAGAGCATGGCTTTTGTTTATGCTTCCGCACTCACTGGTGACCGTAAGTATAA
TGACGCCGTATTTCACCAAGCTTAGCGAGAAAGCTGTTGACAAAGATATGCACGGTTACAGGACCTCGCTGTCAGAGGTT
ATAAGAATCGTATGCCTCGCACTGGTGGGGGGCACAGCTGTTCTAATGGTCTCAGCCTTTCCGCTCGCGCGTATTTTCGC
CACCCAGGAGCATGTTGTGCATTCAATGGCTCTGACCATAATTGCATACTCCCTGGGGCTTGTTGCGTTTAGCACGCTCT
ATATATTGCAAAAAGCTTTTTATGCACTGTGCGATACGCGCACACCGTTCTTTCTCGCGGCCATATGCTCGGGGGTTATC
ATTATCGGCGCTTTGCTGTGCGCCCTGCTTCCCGCGGAATATATCGCTCCGGGCCTTGCGCTTACAGTCAGTCTTTCGAG
TGTGCTTCAATGTGCGCTCGCCTTCTTGGCGATCAGGGTAAAGCTTGGTGGGTTTTCCGTCCGTGAAATAGGCCAAAAGC
TTGCTAGATACACACTTAGTGGTTTGTTGGCTTCCCTTGTGGGGATTGGATTGGCTGTAGGTCTTACCGGATTTTTTTTC
CAGAATCCGGTGAATTCCATCATAACCGTTGTGATGATAGCACTGGTTATGCTGCCAATATACTCGTATTTTCTTGTTAT
AACCCGCTGCCGGGAAATCAGGTTTTTTTTCAAATGA

Upstream 100 bases:

>100_bases
AGCGCACGGCTTTCACATGTAAACAGACTAGCCACGTACACCAATTATCAGAGAGGCGGTAGCCCCATAGCCTAAAAACA
TAAAGTAATGTAGTGCCTGT

Downstream 100 bases:

>100_bases
AGTACAAACGGGTTGTTTTGGAGCGCTCTTGTGAAGTATACAAGCATGTTTAAATTAGCGCTATCGCGCCTGCAAAAACT
GTCACATGAAGACTCGGTCC

Product: integral membrane virulence protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MDTRRASAVMALGTLVSRVIGFLGMILLTYATGSIGSGANAFAVANYLPNMIYAIVAGGTVNAVLIPQVVRFSASGNERY
INKITTLAIVLFAFITLVAAFLSPTLVKITAGAGFDKQTTAVAISFAYWCVPQIFFYAIYSVLGEVLNARKVYGPFTWTP
AINNIVFISGILLFILVFGADPEGSRGAWPPFAIAILGGSATLGIACQALFLLIFWKSAGLRFKPDFNWRGIQITNLGKI
FSWTFFMVVITTIAGLVETNISTLAGNHNASVAVMQRAWLLFMLPHSLVTVSIMTPYFTKLSEKAVDKDMHGYRTSLSEV
IRIVCLALVGGTAVLMVSAFPLARIFATQEHVVHSMALTIIAYSLGLVAFSTLYILQKAFYALCDTRTPFFLAAICSGVI
IIGALLCALLPAEYIAPGLALTVSLSSVLQCALAFLAIRVKLGGFSVREIGQKLARYTLSGLLASLVGIGLAVGLTGFFF
QNPVNSIITVVMIALVMLPIYSYFLVITRCREIRFFFK

Sequences:

>Translated_518_residues
MDTRRASAVMALGTLVSRVIGFLGMILLTYATGSIGSGANAFAVANYLPNMIYAIVAGGTVNAVLIPQVVRFSASGNERY
INKITTLAIVLFAFITLVAAFLSPTLVKITAGAGFDKQTTAVAISFAYWCVPQIFFYAIYSVLGEVLNARKVYGPFTWTP
AINNIVFISGILLFILVFGADPEGSRGAWPPFAIAILGGSATLGIACQALFLLIFWKSAGLRFKPDFNWRGIQITNLGKI
FSWTFFMVVITTIAGLVETNISTLAGNHNASVAVMQRAWLLFMLPHSLVTVSIMTPYFTKLSEKAVDKDMHGYRTSLSEV
IRIVCLALVGGTAVLMVSAFPLARIFATQEHVVHSMALTIIAYSLGLVAFSTLYILQKAFYALCDTRTPFFLAAICSGVI
IIGALLCALLPAEYIAPGLALTVSLSSVLQCALAFLAIRVKLGGFSVREIGQKLARYTLSGLLASLVGIGLAVGLTGFFF
QNPVNSIITVVMIALVMLPIYSYFLVITRCREIRFFFK
>Mature_518_residues
MDTRRASAVMALGTLVSRVIGFLGMILLTYATGSIGSGANAFAVANYLPNMIYAIVAGGTVNAVLIPQVVRFSASGNERY
INKITTLAIVLFAFITLVAAFLSPTLVKITAGAGFDKQTTAVAISFAYWCVPQIFFYAIYSVLGEVLNARKVYGPFTWTP
AINNIVFISGILLFILVFGADPEGSRGAWPPFAIAILGGSATLGIACQALFLLIFWKSAGLRFKPDFNWRGIQITNLGKI
FSWTFFMVVITTIAGLVETNISTLAGNHNASVAVMQRAWLLFMLPHSLVTVSIMTPYFTKLSEKAVDKDMHGYRTSLSEV
IRIVCLALVGGTAVLMVSAFPLARIFATQEHVVHSMALTIIAYSLGLVAFSTLYILQKAFYALCDTRTPFFLAAICSGVI
IIGALLCALLPAEYIAPGLALTVSLSSVLQCALAFLAIRVKLGGFSVREIGQKLARYTLSGLLASLVGIGLAVGLTGFFF
QNPVNSIITVVMIALVMLPIYSYFLVITRCREIRFFFK

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=462, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 55899; Mature: 55899

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRRASAVMALGTLVSRVIGFLGMILLTYATGSIGSGANAFAVANYLPNMIYAIVAGGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
VNAVLIPQVVRFSASGNERYINKITTLAIVLFAFITLVAAFLSPTLVKITAGAGFDKQTT
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHH
AVAISFAYWCVPQIFFYAIYSVLGEVLNARKVYGPFTWTPAINNIVFISGILLFILVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCC
DPEGSRGAWPPFAIAILGGSATLGIACQALFLLIFWKSAGLRFKPDFNWRGIQITNLGKI
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCHHH
FSWTFFMVVITTIAGLVETNISTLAGNHNASVAVMQRAWLLFMLPHSLVTVSIMTPYFTK
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEKAVDKDMHGYRTSLSEVIRIVCLALVGGTAVLMVSAFPLARIFATQEHVVHSMALTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAYSLGLVAFSTLYILQKAFYALCDTRTPFFLAAICSGVIIIGALLCALLPAEYIAPGLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
LTVSLSSVLQCALAFLAIRVKLGGFSVREIGQKLARYTLSGLLASLVGIGLAVGLTGFFF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNPVNSIITVVMIALVMLPIYSYFLVITRCREIRFFFK
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTRRASAVMALGTLVSRVIGFLGMILLTYATGSIGSGANAFAVANYLPNMIYAIVAGGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
VNAVLIPQVVRFSASGNERYINKITTLAIVLFAFITLVAAFLSPTLVKITAGAGFDKQTT
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHH
AVAISFAYWCVPQIFFYAIYSVLGEVLNARKVYGPFTWTPAINNIVFISGILLFILVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCC
DPEGSRGAWPPFAIAILGGSATLGIACQALFLLIFWKSAGLRFKPDFNWRGIQITNLGKI
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCHHH
FSWTFFMVVITTIAGLVETNISTLAGNHNASVAVMQRAWLLFMLPHSLVTVSIMTPYFTK
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEKAVDKDMHGYRTSLSEVIRIVCLALVGGTAVLMVSAFPLARIFATQEHVVHSMALTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAYSLGLVAFSTLYILQKAFYALCDTRTPFFLAAICSGVIIIGALLCALLPAEYIAPGLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
LTVSLSSVLQCALAFLAIRVKLGGFSVREIGQKLARYTLSGLLASLVGIGLAVGLTGFFF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNPVNSIITVVMIALVMLPIYSYFLVITRCREIRFFFK
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]