Definition Tropheryma whipplei TW08/27, complete genome.
Accession NC_004551
Length 925,938

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The map label for this gene is mshA2 [H]

Identifier: 28572948

GI number: 28572948

Start: 914410

End: 915627

Strand: Direct

Name: mshA2 [H]

Synonym: TW807

Alternate gene names: 28572948

Gene position: 914410-915627 (Clockwise)

Preceding gene: 28572943

Following gene: 28572950

Centisome position: 98.75

GC content: 47.29

Gene sequence:

>1218_bases
GTGACCCTTCGCATTGCCATGGTGTCAATGCACAGCCACCCCCTTGCGCAGCCTGGAACCAGTAATGCTGGGGGAATGAA
TGTTTATATCACCGAGGTTGCAAAGCGTCTTGCTGAACTTGAATGCATGGTTGATCTTTTTACCCTATCTAATGAGGATT
ATTCACAAGATATTTTTCGTGGCGTTAGACTAATTGGAATCAAACCGTCAGGACGGATTGGCCCACAGATGGTTGATATG
TTGAATCATGTTCCGGGCTTTGCGCAGAAAATTCTCGAGCATGAGCCGTACGATATATTTCACTCACATTACTGGCTGAG
CGGCATGGCCTCAGATATAGTGAGCTCGCAGCTTGATACGCCACATATTCTGAACATGCACACAATAGGTGCTGTCAAAA
ACACCCTGCTAGCAGAGGGCGATGATCCAGAACCCCCCATTCGACTTGAGAGCGAGAAACGCCTGGCCAGGAAGGTCTCA
AAAGTTATCACATCCACCCTGACCGAAGCGTCGGCTGTTTCGAGATATTACGGAATAAGATTCGAAAATATTGCGGTTGT
ATCGCCGGGTGTTGATACTACAGTTTTTTACCCGAAGGGAAATTGCACTCAAGAAAATGAAGGGGGTAATCATCTTTGGG
CCCCGGTTGCGACCAATCCAGCGGGGTTTTTAGCTGTTCTTTCCAGAATCCAGCCACTAAAAGGGCAAGACCTGGCTATC
CGCACTTTGGCGAGCTTGCGTAAAATCATGTTTGATAAATGCCCAAGCCTGATCATTGCGGGTGATCAATCTGAGAAATA
CAACAACTATGCTGCATCGCTGCGGCGCATGGCATTGGACCTACAAGTTGAGGATCTTGTGCATTTTACCGGAGTCATAA
GCCGCAAGCAGGTTGCTATGGTTATGCGAAACGCACAACTTCTCCTCGTTCCATCGCATTCGGAAACATTTGGTCTCGTA
ACTCTGGAGGCCGCTGCAAGTGGGACGCCGGTTGTCGCAAGTCTAACAGATGGACTTATTGATGCGATTGTTCCGAACAT
AACTGGAATTCTCATTGCCGAGCGAAATCCCGATATTTGGGCAAAAAATATTGCCAATCTGCTTATGAATAAGAACAGAC
ACAAGTCTTTATCACGGTCCTCTGTCAGGCATGCACAAGACCACGACTGGACAAAAACAGCGGCCCAAATACTAAGTCTT
TACCACCAGTTCGTATAA

Upstream 100 bases:

>100_bases
GCAGGGCCAGGCCATACGCAGTACACCGAATCGAAATGTACAGACAGCAGGCGCTGAAGAAATGGAGACTAAAACACATG
TTGCGTATGCGAGTTGAGCG

Downstream 100 bases:

>100_bases
GGCGCGCCAGGCGGTTAGGCAATACACCTGTACGCCTCCAAATCTGGAACTGAGTACCCTTCCCCGGATACGACCTGAAT
TTTTGCCCTCTTTGAATTTG

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 2; GlcNAc-Ins-P N-acetylglucosaminyltransferase 2 [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLSNEDYSQDIFRGVRLIGIKPSGRIGPQMVDM
LNHVPGFAQKILEHEPYDIFHSHYWLSGMASDIVSSQLDTPHILNMHTIGAVKNTLLAEGDDPEPPIRLESEKRLARKVS
KVITSTLTEASAVSRYYGIRFENIAVVSPGVDTTVFYPKGNCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAI
RTLASLRKIMFDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAMVMRNAQLLLVPSHSETFGLV
TLEAAASGTPVVASLTDGLIDAIVPNITGILIAERNPDIWAKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSL
YHQFV

Sequences:

>Translated_405_residues
MTLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLSNEDYSQDIFRGVRLIGIKPSGRIGPQMVDM
LNHVPGFAQKILEHEPYDIFHSHYWLSGMASDIVSSQLDTPHILNMHTIGAVKNTLLAEGDDPEPPIRLESEKRLARKVS
KVITSTLTEASAVSRYYGIRFENIAVVSPGVDTTVFYPKGNCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAI
RTLASLRKIMFDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAMVMRNAQLLLVPSHSETFGLV
TLEAAASGTPVVASLTDGLIDAIVPNITGILIAERNPDIWAKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSL
YHQFV
>Mature_404_residues
TLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLSNEDYSQDIFRGVRLIGIKPSGRIGPQMVDML
NHVPGFAQKILEHEPYDIFHSHYWLSGMASDIVSSQLDTPHILNMHTIGAVKNTLLAEGDDPEPPIRLESEKRLARKVSK
VITSTLTEASAVSRYYGIRFENIAVVSPGVDTTVFYPKGNCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAIR
TLASLRKIMFDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAMVMRNAQLLLVPSHSETFGLVT
LEAAASGTPVVASLTDGLIDAIVPNITGILIAERNPDIWAKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSLY
HQFV

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 44626; Mature: 44495

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLSNEDYSQDIFR
CEEEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
GVRLIGIKPSGRIGPQMVDMLNHVPGFAQKILEHEPYDIFHSHYWLSGMASDIVSSQLDT
CEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PHILNMHTIGAVKNTLLAEGDDPEPPIRLESEKRLARKVSKVITSTLTEASAVSRYYGIR
CCEECCHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FENIAVVSPGVDTTVFYPKGNCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAI
ECCEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHH
RTLASLRKIMFDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAM
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VMRNAQLLLVPSHSETFGLVTLEAAASGTPVVASLTDGLIDAIVPNITGILIAERNPDIW
HHCCCEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCCEEEEEECCCCCHH
AKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSLYHQFV
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLRIAMVSMHSHPLAQPGTSNAGGMNVYITEVAKRLAELECMVDLFTLSNEDYSQDIFR
EEEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
GVRLIGIKPSGRIGPQMVDMLNHVPGFAQKILEHEPYDIFHSHYWLSGMASDIVSSQLDT
CEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PHILNMHTIGAVKNTLLAEGDDPEPPIRLESEKRLARKVSKVITSTLTEASAVSRYYGIR
CCEECCHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FENIAVVSPGVDTTVFYPKGNCTQENEGGNHLWAPVATNPAGFLAVLSRIQPLKGQDLAI
ECCEEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHH
RTLASLRKIMFDKCPSLIIAGDQSEKYNNYAASLRRMALDLQVEDLVHFTGVISRKQVAM
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VMRNAQLLLVPSHSETFGLVTLEAAASGTPVVASLTDGLIDAIVPNITGILIAERNPDIW
HHCCCEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCCEEEEEECCCCCHH
AKNIANLLMNKNRHKSLSRSSVRHAQDHDWTKTAAQILSLYHQFV
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA