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The map label for this gene is fruK [H]

Identifier: 28378718

GI number: 28378718

Start: 1888848

End: 1889765

Strand: Direct

Name: fruK [H]

Synonym: lp_2096

Alternate gene names: 28378718

Gene position: 1888848-1889765 (Clockwise)

Preceding gene: 28378717

Following gene: 28378719

Centisome position: 57.09

GC content: 49.35

Gene sequence:

>918_bases
ATGATTTATACCATTACTGTCAATCCATCAATTGACTACGTGGTGCAACTACCCCAAATGACCCTCGGTAGTGTTAACCG
GTTAGCACACACGGCGAAACTCCCTGGCGGTAAAGGCATCAATGTATCGCAGATTTTGAACGACCTAGACCAACCCAACA
AGGCCCTCGGCTTTATCGGTGGGTTTACCGGCACGTTTATCAGTGATGCTTTAAAAGCCAAGGGCCTAGATTGTCACTTC
ACACCGATTGCCGATGACACCCGGATCAACGTGAAGATTCACGCTGAAGAAGAGACCGAATTAAACGGTGCTGGCCCGGA
CATCACCGCCAAAGAAATAGAAGCCTTCTACACCGAATTGGCCAATTTAACGCCGAATGACGTGGTCGTCATGTCTGGTA
GTTTAGCGCCTAGTTTACCAGATAGCTTCTACTACGATATTATTCAGAAGGTCGAAGCTGCTGGTGCTAACTTTGTCATC
GACACGACCGGTGAAGCTTTGAAGAAAACTTTACCCAGCCACCCCCTCGTTGTGAAGCCTAATAACCACGAACTTGCTGA
TTACTACCACACGACGTTTAATAGCCAGGCTGATATCATTGCAGCGGGCCAGCGGATGCTAGCTGAAGGTGCACAACACG
TGCTGATTTCAATGGCCGGCGATGGTGGCCTCCTAATCACCAAGGATGCGGTCTACTTTAGTCCCGCACCAAAGGGCCAG
GTAATCAACTCAGTTGGTGCCGGTGATTCAATGATTGGTGGCTTTGTCGGCACGTTCGCCAAAACACACGATGCTGTTGA
AAGCTTCCGCTACGGCTTAGCTTGTGGCTCCGCAACCGCCTTCTCAGAAGACATTGCGACCCGCGCCAAGATCGATGAAA
TTTTGCCACTCATTAACATTGAAAAACTCGCTCACTAA

Upstream 100 bases:

>100_bases
GCGTCGGTGATTTATCCAGTGCAACCATCATCACTGACCAACTCACGCCAAGCGTTGCCGAACAGTATCAACCATTAACT
ACGATTCAGGAGGTTCAATC

Downstream 100 bases:

>100_bases
AGAAAGGACTGTTAACTAAACATGGATATCCGCGATTTATTACTAAAAGATGTCATGATCATGGACATGCACGCCACGAC
CAAGGACGAAGCGATTGATG

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIYTITVNPSIDYVVQLPQMTLGSVNRLAHTAKLPGGKGINVSQILNDLDQPNKALGFIGGFTGTFISDALKAKGLDCHF
TPIADDTRINVKIHAEEETELNGAGPDITAKEIEAFYTELANLTPNDVVVMSGSLAPSLPDSFYYDIIQKVEAAGANFVI
DTTGEALKKTLPSHPLVVKPNNHELADYYHTTFNSQADIIAAGQRMLAEGAQHVLISMAGDGGLLITKDAVYFSPAPKGQ
VINSVGAGDSMIGGFVGTFAKTHDAVESFRYGLACGSATAFSEDIATRAKIDEILPLINIEKLAH

Sequences:

>Translated_305_residues
MIYTITVNPSIDYVVQLPQMTLGSVNRLAHTAKLPGGKGINVSQILNDLDQPNKALGFIGGFTGTFISDALKAKGLDCHF
TPIADDTRINVKIHAEEETELNGAGPDITAKEIEAFYTELANLTPNDVVVMSGSLAPSLPDSFYYDIIQKVEAAGANFVI
DTTGEALKKTLPSHPLVVKPNNHELADYYHTTFNSQADIIAAGQRMLAEGAQHVLISMAGDGGLLITKDAVYFSPAPKGQ
VINSVGAGDSMIGGFVGTFAKTHDAVESFRYGLACGSATAFSEDIATRAKIDEILPLINIEKLAH
>Mature_305_residues
MIYTITVNPSIDYVVQLPQMTLGSVNRLAHTAKLPGGKGINVSQILNDLDQPNKALGFIGGFTGTFISDALKAKGLDCHF
TPIADDTRINVKIHAEEETELNGAGPDITAKEIEAFYTELANLTPNDVVVMSGSLAPSLPDSFYYDIIQKVEAAGANFVI
DTTGEALKKTLPSHPLVVKPNNHELADYYHTTFNSQADIIAAGQRMLAEGAQHVLISMAGDGGLLITKDAVYFSPAPKGQ
VINSVGAGDSMIGGFVGTFAKTHDAVESFRYGLACGSATAFSEDIATRAKIDEILPLINIEKLAH

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=258, Percent_Identity=31.7829457364341, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788017, Length=289, Percent_Identity=28.3737024221453, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32449; Mature: 32449

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTITVNPSIDYVVQLPQMTLGSVNRLAHTAKLPGGKGINVSQILNDLDQPNKALGFIG
CEEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHC
GFTGTFISDALKAKGLDCHFTPIADDTRINVKIHAEEETELNGAGPDITAKEIEAFYTEL
CCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
ANLTPNDVVVMSGSLAPSLPDSFYYDIIQKVEAAGANFVIDTTGEALKKTLPSHPLVVKP
HCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEECC
NNHELADYYHTTFNSQADIIAAGQRMLAEGAQHVLISMAGDGGLLITKDAVYFSPAPKGQ
CCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCEEECCCCCCC
VINSVGAGDSMIGGFVGTFAKTHDAVESFRYGLACGSATAFSEDIATRAKIDEILPLINI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKLAH
HHHCC
>Mature Secondary Structure
MIYTITVNPSIDYVVQLPQMTLGSVNRLAHTAKLPGGKGINVSQILNDLDQPNKALGFIG
CEEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHC
GFTGTFISDALKAKGLDCHFTPIADDTRINVKIHAEEETELNGAGPDITAKEIEAFYTEL
CCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
ANLTPNDVVVMSGSLAPSLPDSFYYDIIQKVEAAGANFVIDTTGEALKKTLPSHPLVVKP
HCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEECC
NNHELADYYHTTFNSQADIIAAGQRMLAEGAQHVLISMAGDGGLLITKDAVYFSPAPKGQ
CCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCEEECCCCCCC
VINSVGAGDSMIGGFVGTFAKTHDAVESFRYGLACGSATAFSEDIATRAKIDEILPLINI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKLAH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]